SG11201408419QA - Method for preparing substituted triazolopyridines - Google Patents
Method for preparing substituted triazolopyridinesInfo
- Publication number
- SG11201408419QA SG11201408419QA SG11201408419QA SG11201408419QA SG11201408419QA SG 11201408419Q A SG11201408419Q A SG 11201408419QA SG 11201408419Q A SG11201408419Q A SG 11201408419QA SG 11201408419Q A SG11201408419Q A SG 11201408419QA SG 11201408419Q A SG11201408419Q A SG 11201408419QA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- str
- preparing substituted
- monheim
- english
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Abstract
(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 16 January 2014 (16.01.2014) WIPOIPCT (10) International Publication Number WO 2014/009219 A1 (51) International Patent Classification: C07D 471/04 (2006.01) A61P 35/00 (2006.01) A61K 31/437 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/EP2013/064017 3 July 2013 (03.07.2013) English (30) Priority Data: 12175640.7 10 July 2012 (10.07.2012) 12185590.2 24 September 2012 (24.09.2012) 13170585.7 5 June 2013 (05.06.2013) English EP EP EP (71) Applicant: BAYER PHARMA AKTIENGESELL- SCHAFT [DE/DE]; Miillerstr. 178, 13353 Berlin (DE). (72) Inventors: SCHULZE, Volker; Emil-Czekowski-Str. 5, 16562 Hohen Neuendorf; OT Bergfelde (DE). MAIS, Franz-Josef; Otto-Hahn-Str. 164, 40591 Diisseldorf (DE). (74) Agent: BIP PATENTS; c/o Bayer Intellectual Property GmbH, Creative Campus Monheim, Alfred-Nobel-Str. 10, 40789 Monheim (DE). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(H)) Published: — with international search report (Art. 21(3)) (54) Title: METHOD FOR PREPARING SUBSTITUTED TRIAZOLOPYRIDINES o\ T-H CJ o\ © o (I) T-H (57) Abstract: The present invention relates to methods of preparing substituted triazolopyridine compounds of general formula (I) O as described and defined herein, as well as to intermediate compounds useful in the preparation of said compounds.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12175640 | 2012-07-10 | ||
| EP12185590 | 2012-09-24 | ||
| EP13170585 | 2013-06-05 | ||
| PCT/EP2013/064017 WO2014009219A1 (en) | 2012-07-10 | 2013-07-03 | Method for preparing substituted triazolopyridines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201408419QA true SG11201408419QA (en) | 2015-01-29 |
Family
ID=48793197
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201408419QA SG11201408419QA (en) | 2012-07-10 | 2013-07-03 | Method for preparing substituted triazolopyridines |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US9388177B2 (en) |
| EP (1) | EP2872506A1 (en) |
| JP (1) | JP6238979B2 (en) |
| KR (1) | KR20150040845A (en) |
| CN (1) | CN104603136B (en) |
| AP (1) | AP3778A (en) |
| AU (1) | AU2013289381A1 (en) |
| BR (1) | BR112015000308A2 (en) |
| CA (1) | CA2878481A1 (en) |
| CL (1) | CL2015000038A1 (en) |
| CO (1) | CO7160002A2 (en) |
| CR (1) | CR20150006A (en) |
| DO (1) | DOP2015000007A (en) |
| EA (1) | EA027544B1 (en) |
| HK (1) | HK1206731A1 (en) |
| IL (1) | IL236265A (en) |
| IN (1) | IN2015DN00085A (en) |
| MX (1) | MX2015000348A (en) |
| NZ (1) | NZ703020A (en) |
| PE (1) | PE20150354A1 (en) |
| PH (1) | PH12015500061A1 (en) |
| SG (1) | SG11201408419QA (en) |
| TN (1) | TN2015000008A1 (en) |
| WO (1) | WO2014009219A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014195276A1 (en) * | 2013-06-07 | 2014-12-11 | Bayer Pharma Aktiengesellschaft | Substituted triazolopyridines having activity as mps-1 inhibitors |
| MA38656A1 (en) | 2013-06-11 | 2018-05-31 | Bayer Pharma AG | Combinations for the treatment of cancer comprising an inhibitor of the mps-1 kinase and a mitosis inhibitor |
| PT3008062T (en) * | 2013-06-11 | 2017-06-07 | Bayer Pharma AG | Prodrug derivatives of substituted triazolopyridines |
| AU2016247476B2 (en) | 2015-04-17 | 2021-12-16 | Netherlands Translational Research Center B.V. | Prognostic biomarkers for TTK inhibitor chemotherapy |
| TW201800408A (en) | 2016-06-15 | 2018-01-01 | 拜耳製藥公司 | MPS-1 inhibitors |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2003030937A1 (en) * | 2001-10-05 | 2005-01-20 | 小野薬品工業株式会社 | A therapeutic agent for stress diseases comprising mitochondrial benzodiazepine receptor antagonists |
| WO2005110410A2 (en) * | 2004-05-14 | 2005-11-24 | Abbott Laboratories | Kinase inhibitors as therapeutic agents |
| UA89503C2 (en) * | 2004-09-13 | 2010-02-10 | Х. Луннбек А/С | Substituted aniline derivatives |
| MX2007004179A (en) * | 2004-10-07 | 2007-06-07 | Warner Lambert Co | Triazolopyridine derivatives as antibacterial agents. |
| US20060194823A1 (en) * | 2004-12-22 | 2006-08-31 | Georg Kettschau | Sulfonamido-macrocycles as Tie2 inhibitors and the salts thereof, a pharmaceutical composition comprising these compounds, the method of preparing and the use thereof |
| TW200808802A (en) * | 2006-06-06 | 2008-02-16 | Schering Corp | Imidazopyrazines as protein kinase inhibitors |
| EP1870416A1 (en) * | 2006-06-21 | 2007-12-26 | Bayer Schering Pharma Aktiengesellschaft | Sulphonamido-macrocycles as tie2 inhibitors |
| CA2662074A1 (en) | 2006-08-30 | 2008-03-06 | Cellzome Limited | Triazole derivatives as kinase inhibitors |
| JO3598B1 (en) * | 2006-10-10 | 2020-07-05 | Infinity Discovery Inc | Boronic acids and esters as inhibitors of fatty acid amide hydrolase |
| EA201000130A1 (en) | 2007-07-18 | 2010-08-30 | Новартис Аг | BICYCLIC HETEROARIL COMPOUNDS AND THEIR APPLICATION AS KINASE INHIBITORS |
| KR20100057650A (en) | 2007-08-23 | 2010-05-31 | 아스트라제네카 아베 | 2-anilinopurin-8-ones as inhibitors of ttk/mps1 for the treatment of proliferative disorders |
| CA2691448A1 (en) | 2007-08-31 | 2009-03-05 | Dominique Swinnen | Triazolopyridine compounds and their use as ask inhibitors |
| GB0719803D0 (en) | 2007-10-10 | 2007-11-21 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
| GB0724342D0 (en) * | 2007-12-13 | 2008-01-30 | Prolysis Ltd | Anitbacterial compositions |
| US8530689B2 (en) * | 2008-05-05 | 2013-09-10 | The Trustees Of The University Of Pennsylvania | Processes for the preparation of biphenyl compounds |
| WO2009155527A2 (en) * | 2008-06-19 | 2009-12-23 | Progenics Pharmaceuticals, Inc. | Phosphatidylinositol 3 kinase inhibitors |
| PE20120110A1 (en) | 2009-02-13 | 2012-02-20 | Fovea Pharmaceuticals | [1,2,4] TRIAZOLO [1,5-A] PYRIDINES AS KINASE INHIBITORS |
| CA2760077A1 (en) | 2009-04-29 | 2010-11-04 | Marcus Koppitz | Substituted imidazoquinoxalines |
| MX2011012961A (en) * | 2009-06-05 | 2012-01-30 | Cephalon Inc | PREPARATION AND USES OF 1,2,4-TRIAZOLO [1,5a] PYRIDINE DERIVATIVES. |
| WO2010141360A1 (en) * | 2009-06-05 | 2010-12-09 | Merck Sharp & Dohme Corp. | Biaryl benzotriazole derivatives |
| WO2011026579A1 (en) | 2009-09-04 | 2011-03-10 | Bayer Schering Pharma Aktiengesellschaft | Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors |
| EP2343297A1 (en) * | 2009-11-30 | 2011-07-13 | Bayer Schering Pharma AG | Triazolopyridines |
| EP2343294A1 (en) * | 2009-11-30 | 2011-07-13 | Bayer Schering Pharma AG | Substituted triazolopyridines |
| EP2343295A1 (en) * | 2009-11-30 | 2011-07-13 | Bayer Schering Pharma AG | Triazolopyridine derivates |
| UY33452A (en) * | 2010-06-16 | 2012-01-31 | Bayer Schering Pharma Ag | REPLACED TRIAZOLOPIRIDINS |
| WO2012044567A2 (en) * | 2010-09-30 | 2012-04-05 | Merck Sharp & Dohme Corp. | Imidazole derivatives |
| AU2012244859B2 (en) * | 2011-04-21 | 2017-06-08 | Bayer Intellectual Property Gmbh | Triazolopyridines |
| WO2012160029A1 (en) * | 2011-05-23 | 2012-11-29 | Bayer Intellectual Property Gmbh | Substituted triazolopyridines |
| UA112096C2 (en) * | 2011-12-12 | 2016-07-25 | Байєр Інтеллектуал Проперті Гмбх | SUBSTITUTED TRIASOLOPYRIDINES AND THEIR APPLICATIONS AS TTK INHIBITORS |
-
2013
- 2013-07-03 CN CN201380045913.9A patent/CN104603136B/en not_active Expired - Fee Related
- 2013-07-03 IN IN85DEN2015 patent/IN2015DN00085A/en unknown
- 2013-07-03 EP EP13737181.1A patent/EP2872506A1/en not_active Withdrawn
- 2013-07-03 PE PE2015000017A patent/PE20150354A1/en not_active Application Discontinuation
- 2013-07-03 BR BR112015000308A patent/BR112015000308A2/en not_active IP Right Cessation
- 2013-07-03 AP AP2014008177A patent/AP3778A/en active
- 2013-07-03 US US14/414,164 patent/US9388177B2/en not_active Expired - Fee Related
- 2013-07-03 KR KR20157000338A patent/KR20150040845A/en not_active Application Discontinuation
- 2013-07-03 WO PCT/EP2013/064017 patent/WO2014009219A1/en active Application Filing
- 2013-07-03 AU AU2013289381A patent/AU2013289381A1/en not_active Abandoned
- 2013-07-03 JP JP2015520907A patent/JP6238979B2/en not_active Expired - Fee Related
- 2013-07-03 EA EA201590116A patent/EA027544B1/en not_active IP Right Cessation
- 2013-07-03 CA CA2878481A patent/CA2878481A1/en not_active Abandoned
- 2013-07-03 SG SG11201408419QA patent/SG11201408419QA/en unknown
- 2013-07-03 MX MX2015000348A patent/MX2015000348A/en unknown
- 2013-07-03 NZ NZ703020A patent/NZ703020A/en not_active IP Right Cessation
-
2014
- 2014-12-15 IL IL236265A patent/IL236265A/en not_active IP Right Cessation
-
2015
- 2015-01-07 TN TNP2015000008A patent/TN2015000008A1/en unknown
- 2015-01-08 CL CL2015000038A patent/CL2015000038A1/en unknown
- 2015-01-09 PH PH12015500061A patent/PH12015500061A1/en unknown
- 2015-01-09 CR CR20150006A patent/CR20150006A/en unknown
- 2015-01-09 DO DO2015000007A patent/DOP2015000007A/en unknown
- 2015-01-09 CO CO15004251A patent/CO7160002A2/en unknown
- 2015-07-29 HK HK15107242.4A patent/HK1206731A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL236265A (en) | 2017-07-31 |
| PH12015500061A1 (en) | 2015-03-02 |
| AP2014008177A0 (en) | 2014-12-31 |
| IN2015DN00085A (en) | 2015-05-29 |
| AU2013289381A1 (en) | 2015-01-22 |
| US20150148542A1 (en) | 2015-05-28 |
| JP2015523372A (en) | 2015-08-13 |
| EP2872506A1 (en) | 2015-05-20 |
| BR112015000308A2 (en) | 2017-06-27 |
| IL236265A0 (en) | 2015-02-26 |
| CO7160002A2 (en) | 2015-01-15 |
| CA2878481A1 (en) | 2014-01-16 |
| JP6238979B2 (en) | 2017-11-29 |
| TN2015000008A1 (en) | 2016-06-29 |
| MX2015000348A (en) | 2015-04-14 |
| KR20150040845A (en) | 2015-04-15 |
| US9388177B2 (en) | 2016-07-12 |
| EA027544B1 (en) | 2017-08-31 |
| WO2014009219A1 (en) | 2014-01-16 |
| CR20150006A (en) | 2015-02-16 |
| AP3778A (en) | 2016-08-31 |
| EA201590116A1 (en) | 2015-07-30 |
| DOP2015000007A (en) | 2015-02-15 |
| CL2015000038A1 (en) | 2015-03-13 |
| NZ703020A (en) | 2017-08-25 |
| PE20150354A1 (en) | 2015-03-21 |
| CN104603136B (en) | 2017-06-27 |
| CN104603136A (en) | 2015-05-06 |
| HK1206731A1 (en) | 2016-01-15 |
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