SG11201407518SA - Process for the preparation of rivaroxaban - Google Patents

Process for the preparation of rivaroxaban

Info

Publication number
SG11201407518SA
SG11201407518SA SG11201407518SA SG11201407518SA SG11201407518SA SG 11201407518S A SG11201407518S A SG 11201407518SA SG 11201407518S A SG11201407518S A SG 11201407518SA SG 11201407518S A SG11201407518S A SG 11201407518SA SG 11201407518S A SG11201407518S A SG 11201407518SA
Authority
SG
Singapore
Prior art keywords
international
rivaroxaban
preparation
vihar
palam
Prior art date
Application number
SG11201407518SA
Inventor
Pankaj Kumar Singh
Mukesh Kumar Sharma
Chandra Has Khanduri
Original Assignee
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd
Publication of SG11201407518SA publication Critical patent/SG11201407518SA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 28 November 2013 (28.11.2013) WIPOIPCT (10) International Publication Number WO 2013/175431 A1 (51) International Patent Classification: C07D 413/12 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/IB2013/054280 23 May 2013 (23.05.2013) English English (30) Priority Data: 1591/DEL/2012 24 May 2012 (24.05.2012) IN (71) Applicant: RANBAXY LABORATORIES LIMITED [IN/IN]; Head Office: 12th Floor, Devika Tower, 06 Nehru Place, New Delhi, Delhi 110019 (IN). (72) Inventors: SINGH, Pankaj, Kumar; 23E/16 Dabouli Ratanlal Nagar, Kanpur, Uttar Pradesh 208022 (IN). SHARMA, Mukesh, Kumar; D-1952, Palam Vihar, Gur- gaon, Haryana 122017 (IN). KHANDURI, Chandra, Has; D-1952, Palam Vihar, Gurgaon, Haryana 122017 (IN). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) •t i> i-H o CJ (54) Title: PROCESS FOR THE PREPARATION OF RIVAROXABAN (57) Abstract: The present invention provides processes for the preparation of rivaroxaban. The present invention also provides an intermediate for the preparation of rivaroxaban.
SG11201407518SA 2012-05-24 2013-05-23 Process for the preparation of rivaroxaban SG11201407518SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1591DE2012 2012-05-24
PCT/IB2013/054280 WO2013175431A1 (en) 2012-05-24 2013-05-23 Process for the preparation of rivaroxaban

Publications (1)

Publication Number Publication Date
SG11201407518SA true SG11201407518SA (en) 2014-12-30

Family

ID=54193702

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201407518SA SG11201407518SA (en) 2012-05-24 2013-05-23 Process for the preparation of rivaroxaban

Country Status (5)

Country Link
US (1) US20150133657A1 (en)
EP (1) EP2855465A1 (en)
IN (1) IN2014DN10209A (en)
SG (1) SG11201407518SA (en)
WO (1) WO2013175431A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016150937A1 (en) 2015-03-25 2016-09-29 Lonza Ltd Method for preparation of thiophenecarbonyl chlorides
WO2016199027A1 (en) * 2015-06-08 2016-12-15 Mehta Api Pvt. Ltd. An improved process for preparation of rivaroxaban
KR101880881B1 (en) 2015-11-04 2018-07-20 론자 리미티드 Preparation of thiophene-2-carbonyl chloride using oxalyl chloride
WO2023088229A1 (en) * 2021-11-17 2023-05-25 浙江华海药业股份有限公司 Method for synthesizing rivaroxaban

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100619639B1 (en) 1997-11-07 2006-09-06 파마시아 앤드 업존 캄파니 엘엘씨 Process to Produce Oxazolidinones
DE19962924A1 (en) * 1999-12-24 2001-07-05 Bayer Ag Substituted oxazolidinones and their use
DE10300111A1 (en) * 2003-01-07 2004-07-15 Bayer Healthcare Ag Process for the preparation of 5-chloro-N - ({(5S) -2-oxo-3- [4- (3-oxo-4-morpholinyl) phenyl] -1,3-oxazolidin-5-yl} methyl ) -2-thiophenecarboxamide
DE10322469A1 (en) 2003-05-19 2004-12-16 Bayer Healthcare Ag Heterocyclic compounds
DE102007032347A1 (en) 2007-07-11 2009-01-15 Bayer Healthcare Ag Aminoacyl prodrugs
EP2354128A1 (en) * 2010-02-10 2011-08-10 Sandoz Ag Method for the preparation of rivaroxaban

Also Published As

Publication number Publication date
US20150133657A1 (en) 2015-05-14
EP2855465A1 (en) 2015-04-08
WO2013175431A1 (en) 2013-11-28
IN2014DN10209A (en) 2015-08-07

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