SG11201406112TA - Improved harvest operations for recombinant proteins - Google Patents

Improved harvest operations for recombinant proteins

Info

Publication number
SG11201406112TA
SG11201406112TA SG11201406112TA SG11201406112TA SG11201406112TA SG 11201406112T A SG11201406112T A SG 11201406112TA SG 11201406112T A SG11201406112T A SG 11201406112TA SG 11201406112T A SG11201406112T A SG 11201406112TA SG 11201406112T A SG11201406112T A SG 11201406112TA
Authority
SG
Singapore
Prior art keywords
recombinant proteins
harvest operations
improved harvest
improved
operations
Prior art date
Application number
SG11201406112TA
Inventor
Michael W Laird
John Richard St
Jane V Gunson
Kim Kaleas
Deepa Nadarajah
Rachel Adams
Bradley R Snedecor
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of SG11201406112TA publication Critical patent/SG11201406112TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/42Means for regulation, monitoring, measurement or control, e.g. flow regulation of agitation speed
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
SG11201406112TA 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins SG11201406112TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261616297P 2012-03-27 2012-03-27
PCT/US2013/031383 WO2013148249A1 (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins

Publications (1)

Publication Number Publication Date
SG11201406112TA true SG11201406112TA (en) 2014-10-30

Family

ID=48040433

Family Applications (4)

Application Number Title Priority Date Filing Date
SG10202007206WA SG10202007206WA (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins
SG10201508420VA SG10201508420VA (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins
SG11201406112TA SG11201406112TA (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins
SG10201912877SA SG10201912877SA (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SG10202007206WA SG10202007206WA (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins
SG10201508420VA SG10201508420VA (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201912877SA SG10201912877SA (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins

Country Status (20)

Country Link
US (7) US20140080180A1 (en)
EP (1) EP2831261B1 (en)
JP (4) JP6225162B2 (en)
KR (2) KR102096678B1 (en)
CN (2) CN109880867A (en)
AR (2) AR090340A1 (en)
AU (3) AU2013240280A1 (en)
CA (2) CA2866753C (en)
ES (1) ES2654424T3 (en)
HK (1) HK1207120A1 (en)
HR (1) HRP20171966T1 (en)
IL (1) IL234377B (en)
MX (3) MX365947B (en)
MY (1) MY171729A (en)
PL (1) PL2831261T3 (en)
RU (2) RU2017139267A (en)
SG (4) SG10202007206WA (en)
SI (1) SI2831261T1 (en)
WO (1) WO2013148249A1 (en)
ZA (1) ZA201406434B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102499718B1 (en) * 2016-06-10 2023-02-13 론자 리미티드 Method for stabilizing proteins
MX2019004717A (en) * 2016-11-07 2019-08-05 Seattle Genetics Inc Distribution of engineered-cysteine caps.
WO2019191133A1 (en) * 2018-03-27 2019-10-03 Bristol-Myers Squibb Company Real-time monitoring of protein concentration using ultraviolet signal
CN109725088B (en) * 2019-03-16 2021-05-18 丁立平 Gas chromatography-mass spectrometry combined method for measuring 2-naphthoic acid and derivatives thereof in bean sprouts
CN110305903B (en) * 2019-07-31 2021-10-01 江苏璟泽生物医药有限公司 Recombinant human follicle stimulating hormone and preparation method thereof
CN113155776A (en) * 2021-04-29 2021-07-23 华东交通大学 Prediction method for optimal harvest time of oranges

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2036891B (en) 1978-12-05 1983-05-05 Windsor Smith C Change speed gear
US4515893A (en) 1979-04-26 1985-05-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing complement-fixing monoclonal antibody to human T cells
ZA811368B (en) 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5672347A (en) 1984-07-05 1997-09-30 Genentech, Inc. Tumor necrosis factor antagonists and their use
JPS6147500A (en) 1984-08-15 1986-03-07 Res Dev Corp Of Japan Chimera monoclonal antibody and its preparation
EP0173494A3 (en) 1984-08-27 1987-11-25 The Board Of Trustees Of The Leland Stanford Junior University Chimeric receptors by dna splicing and expression
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
JPS61134325A (en) 1984-12-04 1986-06-21 Teijin Ltd Expression of hybrid antibody gene
AU606320B2 (en) 1985-11-01 1991-02-07 International Genetic Engineering, Inc. Modular assembly of antibody genes, antibodies prepared thereby and use
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
US5091313A (en) 1988-08-05 1992-02-25 Tanox Biosystems, Inc. Antigenic epitopes of IgE present on B cell but not basophil surface
US5720937A (en) 1988-01-12 1998-02-24 Genentech, Inc. In vivo tumor detection assay
DE68919361T2 (en) 1988-06-21 1995-05-24 Genentech Inc THERAPEUTIC COMPOSITIONS FOR THE TREATMENT OF MYOCARD INFARTS.
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
CA2113813C (en) 1991-08-14 2005-04-12 Paula M. Jardieu Immunoglobulin variants for specific fc epsilon receptors
WO1993008829A1 (en) 1991-11-04 1993-05-13 The Regents Of The University Of California Compositions that mediate killing of hiv-infected cells
US5288931A (en) 1991-12-06 1994-02-22 Genentech, Inc. Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation
ATE149570T1 (en) 1992-08-17 1997-03-15 Genentech Inc BISPECIFIC IMMUNOADHESINS
MX9305070A (en) 1992-08-21 1994-04-29 Genentech Inc PHARMACEUTICAL COMPOSITION CONTAINING AN LFA-1 ANTAGONIST FOR THE TREATMENT OF DISORDERS OR DISORDERS MEDIATED BY LFA-1
US5736137A (en) 1992-11-13 1998-04-07 Idec Pharmaceuticals Corporation Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
WO1995016203A2 (en) 1993-12-10 1995-06-15 Genentech, Inc. Methods for diagnosis of allergy and screening of anti-allergy therapeutics
DK0739214T3 (en) 1994-01-18 1998-10-07 Genentech Inc Method of treating parasite infections using IgE antagonists
WO1995023865A1 (en) 1994-03-03 1995-09-08 Genentech, Inc. Anti-il-8 monoclonal antibodies for treatment of inflammatory disorders
US5639635A (en) 1994-11-03 1997-06-17 Genentech, Inc. Process for bacterial production of polypeptides
IL117645A (en) 1995-03-30 2005-08-31 Genentech Inc Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration
CA2222231A1 (en) 1995-06-07 1996-12-19 Imclone Systems Incorporated Antibody and antibody fragments for inhibiting the growth of tumors
EP1297847A3 (en) 1996-01-23 2003-05-07 Genentech, Inc. Anti-CD18 antibodies in stroke
US7147851B1 (en) 1996-08-15 2006-12-12 Millennium Pharmaceuticals, Inc. Humanized immunoglobulin reactive with α4β7 integrin
IL130143A0 (en) 1996-11-27 2000-06-01 Genentech Inc Humanized anti-CD11a antibodies
EP0973804B1 (en) 1997-04-07 2006-12-27 Genentech, Inc. Anti-vegf antibodies
PT1860187E (en) 1997-05-15 2011-10-04 Genentech Inc Apo-2 receptor
US6946129B1 (en) 1999-06-08 2005-09-20 Seattle Genetics, Inc. Recombinant anti-CD40 antibody and uses thereof
IL149116A0 (en) 1999-10-29 2002-11-10 Genentech Inc Anti-prostate stem cell antigen (psca) antibody compositions and methods of use
US6946271B2 (en) * 2000-09-20 2005-09-20 Degussa Ag Nucleotide sequences which code for the menE gene
US6979556B2 (en) 2000-12-14 2005-12-27 Genentech, Inc. Separate-cistron contructs for secretion of aglycosylated antibodies from prokaryotes
DE60332957D1 (en) 2002-12-16 2010-07-22 Genentech Inc IMMUNOGLOBULIN VARIANTS AND ITS USES
EP1607383A4 (en) * 2003-03-26 2006-09-27 Meiji Dairies Corp Method of stabilizing 1,4-dihydroxy-2-naphthoic acid
JP5544063B2 (en) * 2003-08-13 2014-07-09 サンド・アクチエンゲゼルシヤフト Expression vectors, transformed host cells and fermentation methods for the production of recombinant polypeptides
CA2554534C (en) * 2004-02-04 2013-01-08 Merck & Co., Inc. Process for large scale production of plasmid dna by e. coli fermentation
US7361764B2 (en) * 2004-07-27 2008-04-22 Sgx Pharmaceuticals, Inc. Pyrrolo-pyridine kinase modulators
CN101115832A (en) * 2004-11-26 2008-01-30 协和发酵工业株式会社 Industrially useful microorganism
CN103436507B (en) * 2006-05-05 2016-04-20 冈戈根股份有限公司 Phage-derived antimicrobial activities
JP5305615B2 (en) * 2006-06-05 2013-10-02 株式会社Adeka Method for producing menaquinone using gene groups of proteins involved in a novel biosynthetic pathway of menaquinone
AU2007272412B2 (en) * 2006-07-14 2013-11-07 Genentech, Inc. Refolding of recombinant proteins
SI3597659T1 (en) * 2007-07-09 2023-04-28 Genentech, Inc. Prevention of disulfide bond reduction during recombinant production of polypeptides
CN101665798B (en) * 2008-09-06 2012-11-21 浙江我武生物科技股份有限公司 Method for preparing recombinant human serum albumin and interferon alpha fusion protein
CN101503470A (en) * 2008-09-27 2009-08-12 上海交通大学 RhDSL recombinant protein and preparation thereof
JP2010088387A (en) * 2008-10-10 2010-04-22 Waseda Univ Promoter inducing and expressing target protein in actinomycetes

Also Published As

Publication number Publication date
RU2014137554A (en) 2016-05-20
HRP20171966T1 (en) 2018-02-09
ES2654424T3 (en) 2018-02-13
MX2018007677A (en) 2020-11-12
CN104350156B (en) 2019-04-02
MX2019007032A (en) 2019-08-16
KR102096678B1 (en) 2020-04-02
RU2017139267A (en) 2019-02-12
SG10201912877SA (en) 2020-02-27
CN104350156A (en) 2015-02-11
PL2831261T3 (en) 2018-04-30
SG10201508420VA (en) 2015-11-27
US20150225760A1 (en) 2015-08-13
JP2018046825A (en) 2018-03-29
HK1207120A1 (en) 2016-01-22
CA3086730A1 (en) 2013-10-03
US20160130624A1 (en) 2016-05-12
JP2019141049A (en) 2019-08-29
EP2831261A1 (en) 2015-02-04
AU2017202484A1 (en) 2017-05-04
US20140080180A1 (en) 2014-03-20
JP6225162B2 (en) 2017-11-01
CA2866753A1 (en) 2013-10-03
US20230069966A1 (en) 2023-03-09
KR20140148392A (en) 2014-12-31
US20210171997A1 (en) 2021-06-10
US20200199639A1 (en) 2020-06-25
JP2020202849A (en) 2020-12-24
SG10202007206WA (en) 2020-08-28
CA2866753C (en) 2020-09-22
JP2015512259A (en) 2015-04-27
AR090340A1 (en) 2014-11-05
WO2013148249A1 (en) 2013-10-03
KR20200037425A (en) 2020-04-08
ZA201406434B (en) 2017-08-30
MX2014011558A (en) 2014-11-14
US20180291411A1 (en) 2018-10-11
SI2831261T1 (en) 2018-01-31
AU2019226192A1 (en) 2019-09-26
AU2013240280A1 (en) 2014-10-16
CN109880867A (en) 2019-06-14
AU2017202484B2 (en) 2019-06-13
MX365947B (en) 2019-06-19
US9765379B2 (en) 2017-09-19
MY171729A (en) 2019-10-25
EP2831261B1 (en) 2017-10-18
RU2636353C2 (en) 2017-11-22
AR116615A2 (en) 2021-05-26
IL234377B (en) 2021-01-31

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