SG10202107777XA - Antibody-coupled cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide y receptors - Google Patents
Antibody-coupled cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide y receptorsInfo
- Publication number
- SG10202107777XA SG10202107777XA SG10202107777XA SG10202107777XA SG10202107777XA SG 10202107777X A SG10202107777X A SG 10202107777XA SG 10202107777X A SG10202107777X A SG 10202107777XA SG 10202107777X A SG10202107777X A SG 10202107777XA SG 10202107777X A SG10202107777X A SG 10202107777XA
- Authority
- SG
- Singapore
- Prior art keywords
- tyrosine
- neuropeptide
- modulators
- receptors
- antibody
- Prior art date
Links
- 108010069514 Cyclic Peptides Proteins 0.000 title 1
- 102000001189 Cyclic Peptides Human genes 0.000 title 1
- 108050002826 Neuropeptide Y Receptor Proteins 0.000 title 1
- 102000012301 Neuropeptide Y receptor Human genes 0.000 title 1
- JAQGKXUEKGKTKX-HOTGVXAUSA-N Tyr-Tyr Chemical class C([C@H](N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(O)=O)C1=CC=C(O)C=C1 JAQGKXUEKGKTKX-HOTGVXAUSA-N 0.000 title 1
Classifications
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- C07K2319/00—Fusion polypeptide
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SG11201902886SA SG11201902886SA (en) | 2016-10-27 | 2017-10-26 | Cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide y receptors |
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US10513546B2 (en) | 2013-12-18 | 2019-12-24 | President And Fellows Of Harvard College | CRP capture/detection of gram positive bacteria |
JOP20190097A1 (en) * | 2016-10-27 | 2019-04-28 | Janssen Pharmaceutica Nv | Immunoglobulins and uses thereof |
US11780900B2 (en) | 2018-04-25 | 2023-10-10 | Janssen Sciences Ireland Unlimited Company | Glucagon like peptide 1 (GLP-1) fusion peptide coupled cyclic peptide tyrosine tyrosine conjugates and uses thereof |
TW202014433A (en) | 2018-04-25 | 2020-04-16 | 比利時商健生藥品公司 | Glucagon like peptide 1 (glp-1) fusion peptide coupled cyclic peptide tyrosine tyrosine conjugates and uses thereof |
WO2020262590A1 (en) * | 2019-06-28 | 2020-12-30 | 味の素株式会社 | Cyclic peptide production method |
CN114641303A (en) | 2019-11-11 | 2022-06-17 | 勃林格殷格翰国际有限公司 | NPY2 receptor agonists |
CN111494606B (en) * | 2020-04-24 | 2021-12-14 | 广州医科大学 | New application of neuropeptide Y |
BR112022025623A2 (en) | 2020-08-07 | 2023-03-07 | Boehringer Ingelheim Int | SOLUBLE AGONISTS OF NPY2 RECEPTORS |
CN115073556A (en) * | 2021-03-12 | 2022-09-20 | 上海天慈生命科学发展有限公司 | Opioid/neuropeptide FF receptor multi-target cyclic peptide molecule and preparation and application thereof |
WO2022266068A2 (en) * | 2021-06-14 | 2022-12-22 | Resolute Bio, Inc. | Glp-1 receptor agonists having improved pharmacological and drug delivery properties |
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