SG10202107374UA - Novel peptides and combination of peptides for use in immunotherapy and methods for generating scaffolds for the use against pancreatic cancer and other cancers - Google Patents
Novel peptides and combination of peptides for use in immunotherapy and methods for generating scaffolds for the use against pancreatic cancer and other cancersInfo
- Publication number
- SG10202107374UA SG10202107374UA SG10202107374UA SG10202107374UA SG10202107374UA SG 10202107374U A SG10202107374U A SG 10202107374UA SG 10202107374U A SG10202107374U A SG 10202107374UA SG 10202107374U A SG10202107374U A SG 10202107374UA SG 10202107374U A SG10202107374U A SG 10202107374UA
- Authority
- SG
- Singapore
- Prior art keywords
- peptides
- immunotherapy
- cancers
- methods
- combination
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title 2
- 108090000765 processed proteins & peptides Proteins 0.000 title 2
- 206010028980 Neoplasm Diseases 0.000 title 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 title 1
- 238000009169 immunotherapy Methods 0.000 title 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 201000002528 pancreatic cancer Diseases 0.000 title 1
- 208000008443 pancreatic carcinoma Diseases 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
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- A61K39/461—Cellular immunotherapy characterised by the cell type used
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- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K14/7051—T-cell receptor (TcR)-CD3 complex
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/303—Liver or Pancreas
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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- C—CHEMISTRY; METALLURGY
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/72—Increased effector function due to an Fc-modification
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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- C07—ORGANIC CHEMISTRY
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- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US201562182026P | 2015-06-19 | 2015-06-19 | |
GBGB1510771.7A GB201510771D0 (en) | 2015-06-19 | 2015-06-19 | Novel peptides and combination of peptides for use in immunotherapy and methods for generating scaffolds for the use against pancreatic cancer |
Publications (1)
Publication Number | Publication Date |
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SG10202107374UA true SG10202107374UA (en) | 2021-08-30 |
Family
ID=56404071
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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SG10202107374UA SG10202107374UA (en) | 2015-06-19 | 2016-06-17 | Novel peptides and combination of peptides for use in immunotherapy and methods for generating scaffolds for the use against pancreatic cancer and other cancers |
Country Status (21)
Country | Link |
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US (4) | US11485769B2 (es) |
EP (1) | EP3310806A2 (es) |
JP (6) | JP2018518956A (es) |
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SG10202107374UA (en) * | 2015-06-19 | 2021-08-30 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy and methods for generating scaffolds for the use against pancreatic cancer and other cancers |
CN109116024B (zh) * | 2018-06-14 | 2021-04-23 | 郑州大学第一附属医院 | 一种肺癌标志物抗-actr3自身抗体及其应用 |
CN111781356A (zh) * | 2019-04-04 | 2020-10-16 | 清华大学 | 一种胃癌极早期细胞标志和胃癌前病变早期细胞标志及其在诊断试剂盒中的应用 |
CN110791566B (zh) * | 2019-10-29 | 2023-06-27 | 徐州市中心医院 | 人shcbp1基因的用途及相关产品 |
CN111333710B (zh) * | 2020-03-04 | 2021-12-03 | 暨南大学 | C20orf24蛋白缺失突变体及其应用 |
CN113539365B (zh) * | 2020-04-16 | 2024-03-01 | 腾辰生物科技(上海)有限公司 | 用于早期诊断心脑血管疾病的甲基化标志物 |
CN112522209A (zh) * | 2020-12-29 | 2021-03-19 | 郑州大学 | 肿瘤相关抗原p62/IMP2对食管鳞癌影响的研究方法 |
CN113176408B (zh) * | 2021-06-02 | 2022-10-11 | 四川大学华西医院 | 一种甲状腺癌预后情况判断的方法 |
CN113337514B (zh) * | 2021-08-05 | 2021-10-29 | 卡瑞济(北京)生命科技有限公司 | Tcr表达构建体以及其制备方法和用途 |
CN114195903B (zh) * | 2021-12-10 | 2023-02-03 | 中国人民解放军空军军医大学 | 一种重组融合蛋白及其制备治疗炎症性肠病药物的应用 |
CN114377135B (zh) * | 2022-03-15 | 2023-11-24 | 河南大学 | Ppm1g在诊治肺癌中的应用 |
CN115558021B (zh) * | 2022-12-01 | 2023-03-17 | 山东大学 | 一种转录因子、重组细胞及其在制备肿瘤治疗药物的应用 |
CN115612745B (zh) * | 2022-12-19 | 2023-03-21 | 北京大学人民医院 | Ipo7在结直肠癌治疗及预后预测中的应用 |
CN117130645A (zh) * | 2023-10-25 | 2023-11-28 | 山东大学 | 基于大型语言模型和补全引擎的自动程序修复方法及*** |
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WO2003010327A2 (en) | 2001-02-21 | 2003-02-06 | Curagen Corporation | Novel proteins and nucleic acids encoding same |
DE60237917D1 (de) * | 2001-06-05 | 2010-11-18 | Exelixis Inc | Gfats als modifikatoren des p53-wegs und verwendungsverfahren |
US7071172B2 (en) | 2002-04-30 | 2006-07-04 | The University Of North Carolina At Chapel Hill | Secretion signal vectors |
US7332281B2 (en) * | 2004-04-27 | 2008-02-19 | Sagres Discovery, Inc. | Therapeutic targets in cancer |
ATE440107T1 (de) | 2005-09-05 | 2009-09-15 | Immatics Biotechnologies Gmbh | Tumorassoziierte peptide, die hla klasse i oder ii-moleküle binden, und anti-tumor impfstoffe |
EP2562182B1 (en) | 2007-07-27 | 2015-10-07 | Immatics Biotechnologies GmbH | Novel immunogenic epitopes for immunotherapy |
SI2113253T1 (sl) * | 2008-04-30 | 2010-06-30 | Immatics Biotechnologies Gmbh | Nove formulacije s tumorjem povezanih peptidov ki se vežejo na molekule humanega levkocitnega antigena HLA razreda I ali II za cepiva |
JP5475355B2 (ja) | 2009-07-31 | 2014-04-16 | ユニ・チャーム株式会社 | 超音波接合装置及び吸収性物品の製造装置 |
JP5645950B2 (ja) | 2009-11-19 | 2014-12-24 | ローベルト ボツシユ ゲゼルシヤフト ミツト ベシユレンクテル ハフツングRobert Bosch Gmbh | 電気的な蓄積ユニットの電圧を等化するための方法 |
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GB201009222D0 (en) | 2010-06-02 | 2010-07-21 | Immatics Biotechnologies Gmbh | Improved cancer therapy based on tumour associated antigens derived from cyclin D1 |
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EP3501550A1 (en) | 2012-04-02 | 2019-06-26 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins associated with human disease |
EP3004141A4 (en) * | 2013-06-03 | 2017-05-31 | Acetylon Pharmaceuticals, Inc. | Histone deacetylase ( hdac) biomarkers in multiple myeloma |
TWI777195B (zh) * | 2013-08-05 | 2022-09-11 | 德商伊瑪提克斯生物科技有限公司 | 新穎肽類,細胞及其用於治療多種腫瘤的用途,其製造方法及包含其等之醫藥組成物(三) |
GB201319446D0 (en) * | 2013-11-04 | 2013-12-18 | Immatics Biotechnologies Gmbh | Personalized immunotherapy against several neuronal and brain tumors |
SG10202107374UA (en) * | 2015-06-19 | 2021-08-30 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy and methods for generating scaffolds for the use against pancreatic cancer and other cancers |
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