SG10202104804PA - Methods and compositions for dosing in adoptive cell therapy - Google Patents
Methods and compositions for dosing in adoptive cell therapyInfo
- Publication number
- SG10202104804PA SG10202104804PA SG10202104804PA SG10202104804PA SG10202104804PA SG 10202104804P A SG10202104804P A SG 10202104804PA SG 10202104804P A SG10202104804P A SG 10202104804PA SG 10202104804P A SG10202104804P A SG 10202104804PA SG 10202104804P A SG10202104804P A SG 10202104804PA
- Authority
- SG
- Singapore
- Prior art keywords
- dosing
- compositions
- methods
- cell therapy
- adoptive cell
- Prior art date
Links
- 238000011467 adoptive cell therapy Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/48—Blood cells, e.g. leukemia or lymphoma
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Mechanical Engineering (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462066279P | 2014-10-20 | 2014-10-20 | |
US201562162647P | 2015-05-15 | 2015-05-15 | |
US201562168710P | 2015-05-29 | 2015-05-29 | |
US201562215732P | 2015-09-08 | 2015-09-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10202104804PA true SG10202104804PA (en) | 2021-06-29 |
Family
ID=55761449
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10202104804PA SG10202104804PA (en) | 2014-10-20 | 2015-10-20 | Methods and compositions for dosing in adoptive cell therapy |
SG11201703203RA SG11201703203RA (en) | 2014-10-20 | 2015-10-20 | Methods and compositions for dosing in adoptive cell therapy |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201703203RA SG11201703203RA (en) | 2014-10-20 | 2015-10-20 | Methods and compositions for dosing in adoptive cell therapy |
Country Status (13)
Country | Link |
---|---|
US (3) | US10507219B2 (en) |
EP (2) | EP3209690B1 (en) |
JP (3) | JP7057669B2 (en) |
KR (1) | KR20170068598A (en) |
CN (2) | CN107106610A (en) |
AU (1) | AU2015336029B2 (en) |
BR (1) | BR112017008042A2 (en) |
CA (1) | CA2964941A1 (en) |
ES (1) | ES2879612T3 (en) |
IL (2) | IL293714A (en) |
MX (2) | MX2017005106A (en) |
SG (2) | SG10202104804PA (en) |
WO (1) | WO2016064929A1 (en) |
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US20210177896A1 (en) * | 2016-06-02 | 2021-06-17 | Novartis Ag | Therapeutic regimens for chimeric antigen receptor (car)- expressing cells |
JP2019517518A (en) | 2016-06-03 | 2019-06-24 | メモリアル スローン ケタリング キャンサー センター | Adoptive cell therapy as an early treatment option |
CN118021943A (en) * | 2016-07-28 | 2024-05-14 | 诺华股份有限公司 | Combination therapy of chimeric antigen receptor and PD-1 inhibitor |
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CN109689686B (en) | 2016-10-07 | 2020-08-25 | T细胞受体治疗公司 | Compositions and methods for T cell receptor weight programming using fusion proteins |
US11851491B2 (en) | 2016-11-22 | 2023-12-26 | TCR2 Therapeutics Inc. | Compositions and methods for TCR reprogramming using fusion proteins |
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CA3134511A1 (en) * | 2019-03-22 | 2020-10-01 | TCR2 Therapeutics Inc. | Compositions and methods for tcr reprogramming using fusion proteins |
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ES2879612T3 (en) | 2021-11-22 |
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KR20170068598A (en) | 2017-06-19 |
CN117427091A (en) | 2024-01-23 |
AU2015336029B2 (en) | 2021-07-22 |
EP3209690B1 (en) | 2021-05-05 |
BR112017008042A2 (en) | 2017-12-26 |
CA2964941A1 (en) | 2016-04-28 |
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