SG10202101143VA - Quinazoline derivatives used to treat hiv - Google Patents
Quinazoline derivatives used to treat hivInfo
- Publication number
- SG10202101143VA SG10202101143VA SG10202101143VA SG10202101143VA SG10202101143VA SG 10202101143V A SG10202101143V A SG 10202101143VA SG 10202101143V A SG10202101143V A SG 10202101143VA SG 10202101143V A SG10202101143V A SG 10202101143VA SG 10202101143V A SG10202101143V A SG 10202101143VA
- Authority
- SG
- Singapore
- Prior art keywords
- derivatives used
- quinazoline derivatives
- treat hiv
- hiv
- treat
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/84—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462096748P | 2014-12-24 | 2014-12-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10202101143VA true SG10202101143VA (en) | 2021-03-30 |
Family
ID=55305044
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201705215PA SG11201705215PA (en) | 2014-12-24 | 2015-12-23 | Quinazoline derivatives used to treat hiv |
| SG10202101143VA SG10202101143VA (en) | 2014-12-24 | 2015-12-23 | Quinazoline derivatives used to treat hiv |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201705215PA SG11201705215PA (en) | 2014-12-24 | 2015-12-23 | Quinazoline derivatives used to treat hiv |
Country Status (41)
Families Citing this family (28)
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|---|---|---|---|---|
| ES2553449T3 (en) | 2011-07-06 | 2015-12-09 | Gilead Sciences, Inc. | Compounds for HIV treatment |
| TWI699355B (en) * | 2014-12-24 | 2020-07-21 | 美商基利科學股份有限公司 | Quinazoline compounds |
| KR101960624B1 (en) | 2014-12-24 | 2019-03-20 | 길리애드 사이언시즈, 인코포레이티드 | Isoquinoline compounds for the treatment of hiv |
| ES2735087T3 (en) | 2014-12-24 | 2019-12-16 | Gilead Sciences Inc | Fused pyrimidine compounds for HIV treatment |
| KR20230130175A (en) | 2014-12-26 | 2023-09-11 | 에모리 유니버시티 | N4-hydroxycytidine and derivatives and anti-viral uses related thereto |
| TWI808055B (en) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Combination therapies of hdac inhibitors and pd-1 inhibitors |
| TWI794171B (en) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Combination therapies of hdac inhibitors and pd-l1 inhibitors |
| SG10201912535VA (en) | 2016-08-19 | 2020-02-27 | Gilead Sciences Inc | Therapeutic compounds useful for the prophylactic or therapeutic treatment of an hiv virus infection |
| AR112412A1 (en) | 2017-08-17 | 2019-10-23 | Gilead Sciences Inc | CHOLINE SALT FORMS OF AN HIV CAPSID INHIBITOR |
| TWI687415B (en) | 2017-08-17 | 2020-03-11 | 美商基利科學股份有限公司 | Solid forms of an hiv capsid inhibitor |
| BR122022008466B1 (en) | 2017-12-07 | 2023-12-05 | Emory University | USE OF A COMPOUND |
| CA3089590C (en) | 2018-02-15 | 2022-12-06 | Gilead Sciences, Inc. | Pyridine derivatives and their use for treating hiv infection |
| CN116854630A (en) | 2018-02-16 | 2023-10-10 | 吉利德科学公司 | Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections |
| CA3216031A1 (en) | 2018-07-16 | 2020-01-23 | Gilead Sciences, Inc. | Capsid inhibitors for the treatment of hiv |
| WO2020214647A1 (en) | 2019-04-17 | 2020-10-22 | Gilead Sciences, Inc. | Solid forms of an hiv protease inhibitor |
| TW202104210A (en) | 2019-04-17 | 2021-02-01 | 美商基利科學股份有限公司 | Hiv protease inhibitors |
| CA3157275A1 (en) | 2019-11-26 | 2021-06-03 | Elena BEKERMAN | Capsid inhibitors for the prevention of hiv |
| EP4121437A1 (en) | 2020-03-20 | 2023-01-25 | Gilead Sciences, Inc. | Prodrugs of 4'-c-substituted-2-halo-2'-deoxyadenosine nucleosides and methods of making and using the same |
| JP6996032B1 (en) | 2020-04-24 | 2022-01-17 | 大日本住友製薬株式会社 | 2-Heteroarylaminoquinazolinone derivative |
| CA3181690A1 (en) | 2020-06-25 | 2021-12-30 | Chienhung CHOU | Capsid inhibitors for the treatment of hiv |
| CN116437958A (en) | 2020-11-11 | 2023-07-14 | 吉利德科学公司 | Method for identifying HIV patients susceptible to therapy with gp120 CD4 binding site directed antibodies |
| AU2022399845A1 (en) | 2021-12-03 | 2024-05-23 | Gilead Sciences, Inc. | Therapeutic compounds for hiv virus infection |
| CN118369316A (en) | 2021-12-03 | 2024-07-19 | 吉利德科学公司 | Therapeutic compounds for HIV virus infection |
| AU2022401696A1 (en) | 2021-12-03 | 2024-05-09 | Gilead Sciences, Inc. | Therapeutic compounds for hiv virus infection |
| TW202400172A (en) | 2022-04-06 | 2024-01-01 | 美商基利科學股份有限公司 | Bridged tricyclic carbamoylpyridone compounds and uses thereof |
| TW202402280A (en) | 2022-07-01 | 2024-01-16 | 美商基利科學股份有限公司 | Therapeutic compounds useful for the prophylactic or therapeutic treatment of an hiv virus infection |
| US20240083984A1 (en) | 2022-08-26 | 2024-03-14 | Gilead Sciences, Inc. | Dosing and scheduling regimen for broadly neutralizing antibodies |
| WO2024076915A1 (en) | 2022-10-04 | 2024-04-11 | Gilead Sciences, Inc. | 4'-thionucleoside analogues and their pharmaceutical use |
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2015
- 2015-12-18 TW TW104142712A patent/TWI699355B/en active
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- 2015-12-23 CN CN202010295176.XA patent/CN111574464A/en active Pending
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- 2015-12-23 JP JP2017534259A patent/JP6367489B2/en active Active
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- 2015-12-23 EP EP15832711.4A patent/EP3237398B1/en active Active
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- 2015-12-23 CR CR20170281A patent/CR20170281A/en unknown
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- 2015-12-23 EP EP21187414.4A patent/EP3960735B1/en active Active
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- 2015-12-23 BR BR102015032361-1A patent/BR102015032361B1/en active IP Right Grant
- 2015-12-23 MD MDA20170070A patent/MD4650B1/en not_active IP Right Cessation
- 2015-12-23 KR KR1020177020449A patent/KR102049476B1/en active IP Right Grant
- 2015-12-23 EP EP23196262.2A patent/EP4302830A3/en active Pending
- 2015-12-23 EA EA202091115A patent/EA202091115A1/en unknown
- 2015-12-23 HU HUE18213309A patent/HUE058296T2/en unknown
- 2015-12-23 KR KR1020197034431A patent/KR102288855B1/en active IP Right Grant
- 2015-12-23 PT PT15832711T patent/PT3237398T/en unknown
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