SG10202012188VA - Aldose reductase inhibitors and methods of use thereof - Google Patents

Aldose reductase inhibitors and methods of use thereof

Info

Publication number
SG10202012188VA
SG10202012188VA SG10202012188VA SG10202012188VA SG10202012188VA SG 10202012188V A SG10202012188V A SG 10202012188VA SG 10202012188V A SG10202012188V A SG 10202012188VA SG 10202012188V A SG10202012188V A SG 10202012188VA SG 10202012188V A SG10202012188V A SG 10202012188VA
Authority
SG
Singapore
Prior art keywords
methods
reductase inhibitors
aldose reductase
aldose
inhibitors
Prior art date
Application number
SG10202012188VA
Inventor
Andrew Wasmuth
Donald W Landry
Original Assignee
Univ Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Columbia filed Critical Univ Columbia
Publication of SG10202012188VA publication Critical patent/SG10202012188VA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4986Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
SG10202012188VA 2016-06-21 2017-06-21 Aldose reductase inhibitors and methods of use thereof SG10202012188VA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662352784P 2016-06-21 2016-06-21

Publications (1)

Publication Number Publication Date
SG10202012188VA true SG10202012188VA (en) 2021-01-28

Family

ID=60783884

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10202012188VA SG10202012188VA (en) 2016-06-21 2017-06-21 Aldose reductase inhibitors and methods of use thereof
SG11201810642XA SG11201810642XA (en) 2016-06-21 2017-06-21 Aldose reductase inhibitors and methods of use thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201810642XA SG11201810642XA (en) 2016-06-21 2017-06-21 Aldose reductase inhibitors and methods of use thereof

Country Status (23)

Country Link
US (5) US10150779B2 (en)
EP (3) EP3352754B1 (en)
JP (3) JP6895464B2 (en)
CN (1) CN109310674B (en)
AU (3) AU2017281082B2 (en)
BR (1) BR112018076244A2 (en)
CA (1) CA3025081A1 (en)
DK (2) DK3352754T3 (en)
ES (2) ES2836500T3 (en)
FI (1) FI3757107T3 (en)
HK (1) HK1259379A1 (en)
HR (2) HRP20231563T1 (en)
HU (2) HUE052101T2 (en)
IL (3) IL283809B2 (en)
LT (2) LT3757107T (en)
MX (2) MX2018016122A (en)
PL (1) PL3757107T3 (en)
PT (2) PT3757107T (en)
RS (1) RS61239B1 (en)
SG (2) SG10202012188VA (en)
SI (2) SI3352754T1 (en)
WO (1) WO2017223179A1 (en)
ZA (1) ZA201808506B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8916563B2 (en) 2010-07-16 2014-12-23 The Trustees Of Columbia University In The City Of New York Aldose reductase inhibitors and uses thereof
SI3352754T1 (en) * 2016-06-21 2021-03-31 The Trustees Of Columbia University In The City Of New York Aldose reductase inhibitors and methods of use thereof
CA3071114A1 (en) * 2017-07-28 2019-01-31 Applied Therapeutics Inc. Compositions and methods for treating galactosemia
EP3924060A4 (en) * 2019-02-12 2023-03-22 Applied Therapeutics, Inc. Methods for treating cutaneous aging
JP2022519944A (en) * 2019-04-01 2022-03-25 アプライド セラピューティクス インコーポレイテッド Inhibitor of aldose reductase
AU2020363699A1 (en) * 2019-10-08 2022-05-26 Applied Therapeutics, Inc. Aldose reductase inhibitors for treatment of phosphomannomutase 2 deficiency
WO2021202523A1 (en) 2020-03-31 2021-10-07 Applied Therapeutics, Inc. Aldose reductase inhibitors for the treatment of acute respiratory distress syndrome, acute lung inflammation/injury, cardiac injury and anti-viral therapy
JP2023524504A (en) 2020-05-01 2023-06-12 アプライド セラピューティクス, インコーポレイテッド Aldose reductase inhibitors for treating sorbitol dehydrogenase deficiency
US20240033263A1 (en) * 2021-03-18 2024-02-01 Banavara MYLARI Combination of aldose reductase inhibitors and probenecid for the treatment of diabetic complications

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EP0189272A3 (en) * 1985-01-17 1987-08-19 Fujisawa Pharmaceutical Co., Ltd. New furanone derivatives, processes for preparation thereof and use thereof
CA1299178C (en) 1985-11-07 1992-04-21 Banavara Lakshmana Mylari Heterocyclic oxophtalazinyl acetic acids
ES2032749T3 (en) 1985-11-07 1993-03-01 Pfizer Inc. OXOFTALAZINYL-HETERO-CYCLIC ACIDS.
US4939140A (en) 1985-11-07 1990-07-03 Pfizer Inc. Heterocyclic oxophthalazinyl acetic acids
US4868301A (en) * 1987-06-09 1989-09-19 Pfizer Inc. Processes and intermediates for the preparation of oxophthalazinyl acetic acids having benzothiazole or other heterocyclic side chains
WO1989006651A1 (en) 1988-01-19 1989-07-27 Pfizer Inc. 1h-indazole-3-acetic acids as aldose reductase inhibitors
US4954629A (en) 1989-05-11 1990-09-04 Pfizer Inc. Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof
US4996204A (en) 1989-05-11 1991-02-26 Pfizer Inc. Pyrido[2,3-d]pyridazinones as aldose reductase inhibitors
FR2647676A1 (en) 1989-06-05 1990-12-07 Union Pharma Scient Appl New pyridazinone derivatives, processes for preparing them and medicaments containing them which are useful, in particular, as aldose reductase inhibitors
US5304557A (en) 1989-12-15 1994-04-19 Pfizer Inc. Substituted oxoophthalazinyl acetic acids and analogs thereof
JPH0495025A (en) 1990-08-08 1992-03-27 Asahi Chem Ind Co Ltd Aldose reductase inhibitor
WO1994007867A1 (en) * 1992-09-28 1994-04-14 Pfizer Inc. Substituted pyrimidines for control of diabetic complications
WO1997008126A1 (en) 1995-08-28 1997-03-06 American Home Products Corporation Phenoxy acetic acids as aldose reductase inhibitors and antihyperglycemic agents
AU9253798A (en) * 1997-09-23 1999-04-12 Novo Nordisk A/S Modules of protein tyrosine phosphatases (ptpases)
YU59600A (en) 1998-03-31 2002-12-10 The Institute For Pharmaceutical Discovery Inc. Substituted indolealkanoic acids
EP0982306A3 (en) 1998-08-21 2000-07-05 Pfizer Products Inc. Polymorph of zopolrestat monohydrate
US6570013B2 (en) 2000-02-16 2003-05-27 Pfizer Inc Salts of zopolrestat
HUP0303644A3 (en) 2001-03-30 2008-06-30 Pfizer Prod Inc Pyridazinone-derivatives aldose reductase inhibitors, their use and pharmaceutical compositions containing them
WO2003061660A1 (en) 2002-01-23 2003-07-31 Eli Lilly And Company Melanocortin receptor agonists
US20040047919A1 (en) 2002-06-13 2004-03-11 Board Of Regents, The University Of Texas System Methods and compositions involving aldose reductase inhibitors
MXPA04012396A (en) * 2002-06-14 2005-06-17 Sato Fumihiko Prodrugs of imidazole derivatives, for use as proton pump inhibitors in the treatment of e.g. peptic ulcers.
US7572910B2 (en) 2003-02-20 2009-08-11 Pfizer, Inc. Pyridazinone aldose reductase inhibitors
US20070021366A1 (en) 2004-11-19 2007-01-25 Srivastava Satish K Structural-based inhibitors of the glutathione binding site in aldose reductase, methods of screening therefor and methods of use
CN101143868A (en) 2007-09-04 2008-03-19 北京理工大学 Aldose reductase inhibitor structure and use
US8916563B2 (en) 2010-07-16 2014-12-23 The Trustees Of Columbia University In The City Of New York Aldose reductase inhibitors and uses thereof
EP3192796B1 (en) 2010-07-16 2019-09-04 The Trustees of Columbia University in the City of New York Aldose reductase inhibitors and uses thereof
CN102512407B (en) 2011-11-23 2014-05-21 中山大学 Application of utilizing beta-phenylalanine compounds as aldose reductase inhibitors
SI3352754T1 (en) * 2016-06-21 2021-03-31 The Trustees Of Columbia University In The City Of New York Aldose reductase inhibitors and methods of use thereof
US11329472B2 (en) 2018-07-20 2022-05-10 Texas Instruments Incorporated Methods and apparatus to prevent undesired triggering of short circuit or over current protection

Also Published As

Publication number Publication date
CN109310674A (en) 2019-02-05
ES2836500T3 (en) 2021-06-25
IL283809B2 (en) 2024-01-01
IL283809B1 (en) 2023-09-01
PL3757107T3 (en) 2024-03-18
SG11201810642XA (en) 2019-01-30
ES2966094T3 (en) 2024-04-18
US10870658B2 (en) 2020-12-22
US20190300543A1 (en) 2019-10-03
HRP20201905T1 (en) 2021-01-22
FI3757107T3 (en) 2023-12-12
CN109310674B (en) 2022-07-08
ZA201808506B (en) 2020-05-27
RU2019101194A (en) 2020-07-23
EP3352754B1 (en) 2020-09-02
EP3352754A4 (en) 2019-04-17
DK3352754T3 (en) 2020-12-07
SI3352754T1 (en) 2021-03-31
US11498925B2 (en) 2022-11-15
RS61239B1 (en) 2021-01-29
AU2021203801B2 (en) 2023-04-06
LT3352754T (en) 2021-02-25
MX2021014938A (en) 2022-01-24
PT3757107T (en) 2023-12-14
EP4316603A2 (en) 2024-02-07
US20230312599A1 (en) 2023-10-05
US20180237451A1 (en) 2018-08-23
EP3757107A1 (en) 2020-12-30
US20210284652A1 (en) 2021-09-16
HUE064911T2 (en) 2024-04-28
PT3352754T (en) 2020-12-07
AU2021203801A1 (en) 2021-07-15
BR112018076244A2 (en) 2019-03-26
EP4316603A3 (en) 2024-04-17
HK1259379A1 (en) 2019-11-29
IL263631B (en) 2021-07-29
JP7368419B2 (en) 2023-10-24
JP6895464B2 (en) 2021-06-30
US10150779B2 (en) 2018-12-11
HUE052101T2 (en) 2021-04-28
US10647726B2 (en) 2020-05-12
JP2021130719A (en) 2021-09-09
HRP20231563T1 (en) 2024-03-15
LT3757107T (en) 2023-12-11
US20200283451A1 (en) 2020-09-10
CN115160339A (en) 2022-10-11
IL283809A (en) 2021-07-29
RU2019101194A3 (en) 2020-08-31
CA3025081A1 (en) 2017-12-28
EP3352754A1 (en) 2018-08-01
AU2017281082A1 (en) 2018-12-06
SI3757107T1 (en) 2024-02-29
JP2019518779A (en) 2019-07-04
DK3757107T3 (en) 2023-11-27
IL263631A (en) 2019-01-31
MX2018016122A (en) 2019-08-01
IL304979A (en) 2023-10-01
AU2017281082B2 (en) 2021-03-18
AU2023204218A1 (en) 2023-07-27
WO2017223179A1 (en) 2017-12-28
EP3757107B1 (en) 2023-10-25
JP2023171614A (en) 2023-12-01

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