SG10202011624SA - Compositions and methods related to engineered fc constructs - Google Patents

Compositions and methods related to engineered fc constructs

Info

Publication number
SG10202011624SA
SG10202011624SA SG10202011624SA SG10202011624SA SG10202011624SA SG 10202011624S A SG10202011624S A SG 10202011624SA SG 10202011624S A SG10202011624S A SG 10202011624SA SG 10202011624S A SG10202011624S A SG 10202011624SA SG 10202011624S A SG10202011624S A SG 10202011624SA
Authority
SG
Singapore
Prior art keywords
engineered
constructs
compositions
methods related
methods
Prior art date
Application number
SG10202011624SA
Inventor
Jonathan C Lansing
Carlos J Bosques
Daniel Ortiz
Original Assignee
Momenta Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Momenta Pharmaceuticals Inc filed Critical Momenta Pharmaceuticals Inc
Publication of SG10202011624SA publication Critical patent/SG10202011624SA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/468Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0684Cells of the urinary tract or kidneys
    • C12N5/0686Kidney cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/524CH2 domain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/526CH3 domain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/53Hinge
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
SG10202011624SA 2016-05-23 2017-05-23 Compositions and methods related to engineered fc constructs SG10202011624SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662340322P 2016-05-23 2016-05-23
US201762443451P 2017-01-06 2017-01-06

Publications (1)

Publication Number Publication Date
SG10202011624SA true SG10202011624SA (en) 2021-01-28

Family

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Family Applications (3)

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SG10202011624SA SG10202011624SA (en) 2016-05-23 2017-05-23 Compositions and methods related to engineered fc constructs
SG11201810465RA SG11201810465RA (en) 2016-05-23 2017-05-23 Compositions and methods related to engineered fc constructs
SG11201810466PA SG11201810466PA (en) 2016-05-23 2017-05-23 Compositions and methods related to engineered fc constructs

Family Applications After (2)

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SG11201810465RA SG11201810465RA (en) 2016-05-23 2017-05-23 Compositions and methods related to engineered fc constructs
SG11201810466PA SG11201810466PA (en) 2016-05-23 2017-05-23 Compositions and methods related to engineered fc constructs

Country Status (12)

Country Link
US (4) US11623964B2 (en)
EP (2) EP3484514B1 (en)
JP (4) JP7045333B6 (en)
KR (3) KR102462084B1 (en)
CN (3) CN109789203B (en)
AU (2) AU2017272111A1 (en)
BR (2) BR112018074032A2 (en)
CA (2) CA3025306A1 (en)
DK (1) DK3484514T3 (en)
IL (3) IL309293A (en)
SG (3) SG10202011624SA (en)
WO (2) WO2017205434A1 (en)

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US11623964B2 (en) 2016-05-23 2023-04-11 Momenta Pharmaceuticals, Inc. Compositions and methods related to engineered Fc constructs
SG11201906139VA (en) 2017-01-06 2019-08-27 Momenta Pharmaceuticals Inc Compositions and methods related to engineered fc constructs
CN113395978A (en) * 2018-07-11 2021-09-14 动量制药公司 Compositions and methods related to engineered Fc-antigen binding domain constructs targeting CTLA-4
KR20210044218A (en) * 2018-07-11 2021-04-22 모멘타 파머슈티컬스 인코포레이티드 Compositions and methods related to CD38 targeting engineered Fc-antigen binding domain constructs
CN112996910A (en) * 2018-07-11 2021-06-18 动量制药公司 Compositions and methods related to engineered Fc-antigen binding domain constructs targeting PD-L1
CA3106254A1 (en) * 2018-07-11 2020-01-16 Momenta Pharmaceuticals, Inc. Compositions and methods related to engineered fc-antigen binding domain constructs
KR20210043583A (en) * 2018-07-11 2021-04-21 모멘타 파머슈티컬스 인코포레이티드 Compositions and methods related to engineered Fc-antigen binding domain constructs
AU2019302662A1 (en) * 2018-07-11 2021-02-25 Momenta Pharmaceuticals, Inc. Compositions and methods related to engineered Fc-antigen binding domain constructs targeted to CCR4
MX2021000280A (en) * 2018-07-11 2021-11-12 Momenta Pharmaceuticals Inc COMPOSITIONS AND METHODS RELATED TO ENGINEERED Fc-ANTIGEN BINDING DOMAIN CONSTRUCTS.
CN113164591A (en) * 2018-07-11 2021-07-23 动量制药公司 Compositions and methods relating to engineered Fc-antigen binding domain constructs
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Also Published As

Publication number Publication date
KR20190021255A (en) 2019-03-05
US11155640B2 (en) 2021-10-26
AU2017272109A1 (en) 2019-01-17
KR102590061B1 (en) 2023-10-18
US20190284305A1 (en) 2019-09-19
SG11201810465RA (en) 2018-12-28
BR112018074032A2 (en) 2019-02-26
JP2022068176A (en) 2022-05-09
CN116063540A (en) 2023-05-05
WO2017205436A1 (en) 2017-11-30
EP3484514A1 (en) 2019-05-22
IL263211B2 (en) 2023-09-01
JP2019519528A (en) 2019-07-11
KR20220151025A (en) 2022-11-11
KR102635635B1 (en) 2024-02-14
CA3025310A1 (en) 2017-11-30
CA3025306A1 (en) 2017-11-30
KR20190026684A (en) 2019-03-13
EP3484514B1 (en) 2023-12-06
US11623964B2 (en) 2023-04-11
JP7295301B2 (en) 2023-06-20
WO2017205434A1 (en) 2017-11-30
US20240067757A1 (en) 2024-02-29
EP3464376A1 (en) 2019-04-10
US20220049019A1 (en) 2022-02-17
EP3464376A4 (en) 2020-03-18
US20210221917A1 (en) 2021-07-22
BR112018074056A2 (en) 2019-03-06
IL263213B1 (en) 2024-01-01
IL263211A (en) 2018-12-31
IL263213A (en) 2018-12-31
DK3484514T3 (en) 2024-01-29
EP3484514A4 (en) 2020-08-12
AU2017272111A1 (en) 2019-01-17
JP7045333B6 (en) 2022-05-06
JP2019519527A (en) 2019-07-11
IL263211B1 (en) 2023-05-01
JP2022095685A (en) 2022-06-28
IL309293A (en) 2024-02-01
KR102462084B1 (en) 2022-11-02
CN109789203B (en) 2022-08-05
JP7045333B2 (en) 2022-03-31
CN109789203A (en) 2019-05-21
SG11201810466PA (en) 2018-12-28
CN109963869A (en) 2019-07-02

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