SG10202010279YA - Compositions and methods of inhibiting masp-3 for the treatment of various diseases and disorders - Google Patents
Compositions and methods of inhibiting masp-3 for the treatment of various diseases and disordersInfo
- Publication number
- SG10202010279YA SG10202010279YA SG10202010279YA SG10202010279YA SG10202010279YA SG 10202010279Y A SG10202010279Y A SG 10202010279YA SG 10202010279Y A SG10202010279Y A SG 10202010279YA SG 10202010279Y A SG10202010279Y A SG 10202010279YA SG 10202010279Y A SG10202010279Y A SG 10202010279YA
- Authority
- SG
- Singapore
- Prior art keywords
- disorders
- compositions
- treatment
- methods
- various diseases
- Prior art date
Links
- 208000037765 diseases and disorders Diseases 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y25/00—Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
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- C—CHEMISTRY; METALLURGY
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- C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
- C01F17/00—Compounds of rare earth metals
- C01F17/20—Compounds containing only rare earth metals as the metal element
- C01F17/206—Compounds containing only rare earth metals as the metal element oxide or hydroxide being the only anion
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
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- C—CHEMISTRY; METALLURGY
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- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
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- C12Y—ENZYMES
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- C12Y304/21104—Mannan-binding lectin-associated serine protease-2 (3.4.21.104)
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- H01F1/0036—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties showing low dimensional magnetism, i.e. spin rearrangements due to a restriction of dimensions, e.g. showing giant magnetoresistivity
- H01F1/0045—Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C07—ORGANIC CHEMISTRY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US201662369674P | 2016-08-01 | 2016-08-01 | |
US201662419420P | 2016-11-08 | 2016-11-08 | |
US201762478336P | 2017-03-29 | 2017-03-29 |
Publications (1)
Publication Number | Publication Date |
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SG10202010279YA true SG10202010279YA (en) | 2020-11-27 |
Family
ID=61073545
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10202010277SA SG10202010277SA (en) | 2016-08-01 | 2017-07-31 | Compositions and methods of inhibiting masp-3 for the treatment of various diseases and disorders |
SG11201900606VA SG11201900606VA (en) | 2016-08-01 | 2017-07-31 | Compositions and methods of inhibiting masp-3 for the treatment of various diseases and disorders |
SG10202010279YA SG10202010279YA (en) | 2016-08-01 | 2017-07-31 | Compositions and methods of inhibiting masp-3 for the treatment of various diseases and disorders |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
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SG10202010277SA SG10202010277SA (en) | 2016-08-01 | 2017-07-31 | Compositions and methods of inhibiting masp-3 for the treatment of various diseases and disorders |
SG11201900606VA SG11201900606VA (en) | 2016-08-01 | 2017-07-31 | Compositions and methods of inhibiting masp-3 for the treatment of various diseases and disorders |
Country Status (25)
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US (4) | US10639369B2 (en) |
EP (1) | EP3490603A4 (en) |
JP (3) | JP6971306B2 (en) |
KR (3) | KR102624948B1 (en) |
CN (4) | CN116333146A (en) |
AU (4) | AU2017306069B2 (en) |
BR (1) | BR112019001247A2 (en) |
CA (3) | CA3122348A1 (en) |
CL (1) | CL2019000230A1 (en) |
CO (1) | CO2019001212A2 (en) |
CR (1) | CR20190105A (en) |
CU (1) | CU24568B1 (en) |
EC (1) | ECSP19015192A (en) |
GE (1) | GEP20247593B (en) |
IL (3) | IL298689B2 (en) |
JO (6) | JOP20170154B1 (en) |
MA (1) | MA45798A (en) |
MX (3) | MX2019000965A (en) |
PE (1) | PE20190389A1 (en) |
PH (1) | PH12019500204A1 (en) |
SA (1) | SA519400950B1 (en) |
SG (3) | SG10202010277SA (en) |
TW (4) | TWI756248B (en) |
UY (1) | UY37349A (en) |
WO (1) | WO2018026722A1 (en) |
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WO2017035401A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Amide compounds for treatment of immune and inflammatory disorders |
WO2017035405A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Amino compounds for treatment of immune and inflammatory disorders |
WO2018160891A1 (en) | 2017-03-01 | 2018-09-07 | Achillion Pharmaceutical, Inc. | Pharmaceutical compounds for treatment of medical disorders |
AU2018227849B2 (en) | 2017-03-01 | 2022-04-28 | Achillion Pharmaceuticals, Inc. | Aryl, heteroary, and heterocyclic pharmaceutical compounds for treatment of medical disorders |
WO2019227102A1 (en) * | 2018-05-25 | 2019-11-28 | Achillion Pharmaceuticals, Inc. | Complement alternative pathway-associated nephropathy biomarkers |
WO2020051532A2 (en) | 2018-09-06 | 2020-03-12 | Achillion Pharmaceuticals, Inc. | Macrocyclic compounds for the treatment of medical disorders |
KR20210057086A (en) | 2018-09-06 | 2021-05-20 | 아칠리온 파르마세우티칼스 인코포레이티드 | The morphological form of Danicopan |
CN112996497A (en) | 2018-09-25 | 2021-06-18 | 艾其林医药公司 | Morphic forms of complement factor D inhibitors |
CN110244053B (en) * | 2019-05-09 | 2022-03-11 | 北京大学第三医院(北京大学第三临床医学院) | Molecular marker for diagnosing lupus nephritis and pulmonary hypertension disease and application thereof |
CN112812182B (en) * | 2019-11-15 | 2023-01-06 | 深圳宾德生物技术有限公司 | FGFR 4-targeted single-chain antibody, chimeric antigen receptor T cell, and preparation method and application thereof |
US20230080534A1 (en) * | 2020-01-21 | 2023-03-16 | Shanghai Biotroy Biotechnique Co., Ltd. | Semg2 antibody and use thereof |
KR20230047492A (en) * | 2020-08-18 | 2023-04-07 | 오메로스 코포레이션 | Monoclonal antibodies, compositions and methods for detection of complement factor D |
CN112950324B (en) * | 2021-03-15 | 2022-06-03 | 重庆邮电大学 | Knowledge graph assisted pairwise sorting personalized merchant recommendation method and system |
CN115304670A (en) * | 2021-05-07 | 2022-11-08 | 华南农业大学 | Murine monoclonal antibody of feline coronavirus nucleocapsid protein, and coding gene and application thereof |
WO2023173036A2 (en) * | 2022-03-10 | 2023-09-14 | Omeros Corporation | Masp-2 and masp-3 inhibitors, and related compositions and methods, for treatment of sickle cell disease |
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