SG10202008076RA - Chimeric antigen receptors targeting fc receptor-like 5 and uses thereof - Google Patents

Chimeric antigen receptors targeting fc receptor-like 5 and uses thereof

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Publication number
SG10202008076RA
SG10202008076RA SG10202008076RA SG10202008076RA SG10202008076RA SG 10202008076R A SG10202008076R A SG 10202008076RA SG 10202008076R A SG10202008076R A SG 10202008076RA SG 10202008076R A SG10202008076R A SG 10202008076RA SG 10202008076R A SG10202008076R A SG 10202008076RA
Authority
SG
Singapore
Prior art keywords
receptor
chimeric antigen
antigen receptors
receptors targeting
targeting
Prior art date
Application number
SG10202008076RA
Inventor
Renier Brentjens
Eric Smith
Cheng Liu
Original Assignee
Memorial Sloan Kettering Cancer Center
Eureka Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Memorial Sloan Kettering Cancer Center, Eureka Therapeutics Inc filed Critical Memorial Sloan Kettering Cancer Center
Publication of SG10202008076RA publication Critical patent/SG10202008076RA/en

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    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • C12N5/0602—Vertebrate cells
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    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
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    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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SG10202008076RA 2014-12-05 2015-12-04 Chimeric antigen receptors targeting fc receptor-like 5 and uses thereof SG10202008076RA (en)

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EP (1) EP3227436A4 (en)
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AU (2) AU2015357543B2 (en)
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MY192062A (en) 2014-12-05 2022-07-25 Memorial Sloan Kettering Cancer Center Chimeric antigen receptors targeting fc receptor-like 5 and uses thereof
CN108337890B (en) * 2015-06-23 2021-10-15 纪念斯隆-凯特琳癌症中心 Novel PD-1 immunomodulators
AU2016362402A1 (en) * 2015-12-04 2018-06-28 Eureka Therapeutics, Inc. Antibodies targeting Fc receptor-like 5 and methods of use
US11542332B2 (en) 2016-03-26 2023-01-03 Bioatla, Inc. Anti-CTLA4 antibodies, antibody fragments, their immunoconjugates and uses thereof
AU2018258046A1 (en) 2017-04-26 2019-12-12 Eureka Therapeutics, Inc. Cells expressing chimeric activating receptors and chimeric stimulating receptors and uses thereof
US20190194340A1 (en) * 2017-09-29 2019-06-27 Cell Design Labs, Inc. Methods of making bispecific anti-cd307e and anti-bcma chimeric antigen receptors and uses of the same
US11866785B2 (en) 2017-10-27 2024-01-09 Board Of Regents, The University Of Texas System Tumor specific antibodies and T-cell receptors and methods of identifying the same
TW201925782A (en) 2017-11-30 2019-07-01 瑞士商諾華公司 BCMA-targeting chimeric antigen receptor, and uses thereof
EP4268848A3 (en) * 2017-12-29 2024-01-10 AP Biosciences, Inc. Monospecific and bispecific proteins with immune checkpoint regulation for cancer therapy
EP3737692A4 (en) * 2018-01-09 2021-09-29 Elstar Therapeutics, Inc. Calreticulin binding constructs and engineered t cells for the treatment of diseases
CA3085467A1 (en) * 2018-02-28 2019-09-06 Ap Biosciences, Inc. Bifunctional proteins combining checkpoint blockade for targeted therapy
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