SG10202005849RA - Methods and compositions for diagnosis and treatment of cancer - Google Patents

Methods and compositions for diagnosis and treatment of cancer

Info

Publication number
SG10202005849RA
SG10202005849RA SG10202005849RA SG10202005849RA SG10202005849RA SG 10202005849R A SG10202005849R A SG 10202005849RA SG 10202005849R A SG10202005849R A SG 10202005849RA SG 10202005849R A SG10202005849R A SG 10202005849RA SG 10202005849R A SG10202005849R A SG 10202005849RA
Authority
SG
Singapore
Prior art keywords
diagnosis
cancer
compositions
treatment
methods
Prior art date
Application number
SG10202005849RA
Inventor
Ugur Sahin
Özlem Türeci
Michael Koslowski
Gerd Helftenbein
Korden Walter
Stefan Wöll
Gabriela-Elena Oprea
Original Assignee
Ganymed Pharmaceuticals Gmbh
Univ Mainz Johannes Gutenberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP09002452A external-priority patent/EP2221375A1/en
Application filed by Ganymed Pharmaceuticals Gmbh, Univ Mainz Johannes Gutenberg filed Critical Ganymed Pharmaceuticals Gmbh
Publication of SG10202005849RA publication Critical patent/SG10202005849RA/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57449—Specifically defined cancers of ovaries
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57423—Specifically defined cancers of lung
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease
SG10202005849RA 2009-02-20 2010-02-19 Methods and compositions for diagnosis and treatment of cancer SG10202005849RA (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US15416709P 2009-02-20 2009-02-20
EP09002452A EP2221375A1 (en) 2009-02-20 2009-02-20 Methods and compositions for diagnosis and treatment of cancer
US23184309P 2009-08-06 2009-08-06
EP09010164 2009-08-06
US26013509P 2009-11-11 2009-11-11
EP09014135 2009-11-11

Publications (1)

Publication Number Publication Date
SG10202005849RA true SG10202005849RA (en) 2020-07-29

Family

ID=42114454

Family Applications (3)

Application Number Title Priority Date Filing Date
SG2011052875A SG173444A1 (en) 2009-02-20 2010-02-19 Methods and compositions for diagnosis and treatment of cancer
SG10202005849RA SG10202005849RA (en) 2009-02-20 2010-02-19 Methods and compositions for diagnosis and treatment of cancer
SG10201402493UA SG10201402493UA (en) 2009-02-20 2010-02-19 Methods and compositions for diagnosis and treatment of cancer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG2011052875A SG173444A1 (en) 2009-02-20 2010-02-19 Methods and compositions for diagnosis and treatment of cancer

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201402493UA SG10201402493UA (en) 2009-02-20 2010-02-19 Methods and compositions for diagnosis and treatment of cancer

Country Status (22)

Country Link
US (4) US9809815B2 (en)
EP (2) EP2398902B1 (en)
JP (1) JP5808254B2 (en)
KR (3) KR102152997B1 (en)
CN (2) CN107028969A (en)
AU (2) AU2010215700B2 (en)
BR (1) BRPI1008564B1 (en)
CA (1) CA2750985C (en)
DK (1) DK2398902T3 (en)
ES (1) ES2963717T3 (en)
FI (1) FI2398902T3 (en)
HR (1) HRP20231525T1 (en)
IL (4) IL214256A0 (en)
LT (1) LT2398902T (en)
MX (3) MX345316B (en)
NZ (1) NZ594480A (en)
PL (1) PL2398902T3 (en)
PT (1) PT2398902T (en)
RS (1) RS64937B1 (en)
SG (3) SG173444A1 (en)
WO (1) WO2010094499A1 (en)
ZA (1) ZA201105471B (en)

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EP2166021A1 (en) * 2008-09-16 2010-03-24 Ganymed Pharmaceuticals AG Monoclonal antibodies for treatment of cancer
EP2221063A1 (en) 2009-02-20 2010-08-25 Ganymed Pharmaceuticals AG Methods and compositions for diagnosis and treatment of cancer
US9809815B2 (en) 2009-02-20 2017-11-07 Ganymed Pharmaceuticals Ag Methods and compositions for diagnosis and treatment of cancer
NZ716587A (en) 2009-11-11 2017-10-27 Ganymed Pharmaceuticals Ag Antibodies specific for claudin 6 (cldn6)
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EP2371864A1 (en) 2010-03-23 2011-10-05 Ganymed Pharmaceuticals AG Monoclonal antibodies for treatment of cancer
EP2404936A1 (en) * 2010-07-06 2012-01-11 Ganymed Pharmaceuticals AG Cancer therapy using CLDN6 target-directed antibodies in vivo
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CN111164208B (en) 2017-09-29 2023-08-04 第一三共株式会社 Antibody-pyrrolobenzodiazepine derivative conjugates

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Also Published As

Publication number Publication date
MX361432B (en) 2018-12-05
SG10201402493UA (en) 2014-10-30
IL214256A0 (en) 2011-09-27
EP2398902B1 (en) 2023-10-04
CA2750985C (en) 2022-07-19
ES2963717T3 (en) 2024-04-01
US11473085B2 (en) 2022-10-18
HRP20231525T1 (en) 2024-03-15
CN102325885A (en) 2012-01-18
KR20200105549A (en) 2020-09-07
EP4285911A2 (en) 2023-12-06
EP2398902A1 (en) 2011-12-28
NZ594480A (en) 2013-11-29
US20190169614A1 (en) 2019-06-06
MX2011008430A (en) 2011-09-29
KR20180098701A (en) 2018-09-04
RS64937B1 (en) 2024-01-31
KR20110128316A (en) 2011-11-29
CA2750985A1 (en) 2010-08-26
DK2398902T3 (en) 2023-12-04
AU2016201051A1 (en) 2016-03-10
IL267342B (en) 2021-12-01
IL236516B (en) 2018-05-31
LT2398902T (en) 2023-12-27
MX345316B (en) 2017-01-23
KR102340685B1 (en) 2021-12-17
CN107028969A (en) 2017-08-11
SG173444A1 (en) 2011-09-29
JP5808254B2 (en) 2015-11-10
PL2398902T3 (en) 2024-02-26
US20230193261A1 (en) 2023-06-22
JP2012518609A (en) 2012-08-16
EP4285911A3 (en) 2024-04-10
IL236516A0 (en) 2015-02-26
ZA201105471B (en) 2012-10-31
US20180119146A1 (en) 2018-05-03
KR102152997B1 (en) 2020-09-07
FI2398902T3 (en) 2023-11-28
PT2398902T (en) 2023-12-05
AU2016201051B2 (en) 2018-02-08
US9809815B2 (en) 2017-11-07
BRPI1008564A2 (en) 2018-02-27
IL267342A (en) 2019-08-29
IL258794B (en) 2019-06-30
AU2010215700B2 (en) 2015-11-19
AU2010215700A1 (en) 2011-08-18
US20110300144A1 (en) 2011-12-08
BRPI1008564B1 (en) 2021-10-05
IL258794A (en) 2018-06-28
WO2010094499A1 (en) 2010-08-26

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