SG10202003090VA - PI3K δ INHIBITOR - Google Patents
PI3K δ INHIBITORInfo
- Publication number
- SG10202003090VA SG10202003090VA SG10202003090VA SG10202003090VA SG10202003090VA SG 10202003090V A SG10202003090V A SG 10202003090VA SG 10202003090V A SG10202003090V A SG 10202003090VA SG 10202003090V A SG10202003090V A SG 10202003090VA SG 10202003090V A SG10202003090V A SG 10202003090VA
- Authority
- SG
- Singapore
- Prior art keywords
- pi3k
- inhibitor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201210279961 | 2012-08-08 | ||
CN201210529334 | 2012-12-10 | ||
CN201310130010 | 2013-04-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10202003090VA true SG10202003090VA (en) | 2020-05-28 |
Family
ID=50067418
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201501173SA SG11201501173SA (en) | 2012-08-08 | 2013-08-08 | PI3Kδ INHIBITOR |
SG10202003090VA SG10202003090VA (en) | 2012-08-08 | 2013-08-08 | PI3K δ INHIBITOR |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201501173SA SG11201501173SA (en) | 2012-08-08 | 2013-08-08 | PI3Kδ INHIBITOR |
Country Status (3)
Country | Link |
---|---|
CN (1) | CN104768952B (en) |
SG (2) | SG11201501173SA (en) |
WO (1) | WO2014023083A1 (en) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6667300B2 (en) | 2000-04-25 | 2003-12-23 | Icos Corporation | Inhibitors of human phosphatidylinositol 3-kinase delta |
ES2605792T3 (en) | 2004-05-13 | 2017-03-16 | Icos Corporation | Quinazolinone used as a human phosphatidylinositol 3-kinase delta inhibitor |
MX2016003456A (en) | 2013-09-22 | 2017-05-25 | Calitor Sciences Llc | Substituted aminopyrimidine compounds and methods of use. |
US9708327B2 (en) | 2013-12-20 | 2017-07-18 | Gilead Calistoga Llc | Polymorphic forms of a hydrochloride salt of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one |
MX2016008259A (en) | 2013-12-20 | 2016-10-13 | Gilead Calistoga Llc | Process methods for phosphatidylinositol 3-kinase inhibitors. |
EA201692267A1 (en) | 2014-06-13 | 2017-06-30 | Джилид Сайэнс, Инк. | PHOSPHATIDYLINOSITOL-3-KINASE INHIBITORS |
MX2016016530A (en) * | 2014-06-13 | 2017-03-27 | Gilead Sciences Inc | Phosphatidylinositol 3-kinase inhibitors. |
BR112016028818A2 (en) * | 2014-06-13 | 2017-08-22 | Gilead Sciences Inc | pharmaceutical composition, methods of treating a disease or condition, inhibiting the activity of a phosphatidylinositol 3-kinase polypeptide and inhibiting excessive or destructive immune reactions or cancer cell growth or proliferation, kit, compound, salt, isomer, or a pharmaceutically acceptable mixture thereof, and, use of a compound, a salt, isomer, or a pharmaceutically acceptable mixture thereof. |
MX2016016538A (en) | 2014-06-13 | 2017-05-01 | Gilead Sciences Inc | Quinazolinone derivatives as phosphatidylinositol 3-kinase inhibitors. |
UA115296C2 (en) | 2014-07-04 | 2017-10-10 | Люпін Лімітед | Quinolizinone derivatives as pi3k inhibitors |
US9708348B2 (en) | 2014-10-03 | 2017-07-18 | Infinity Pharmaceuticals, Inc. | Trisubstituted bicyclic heterocyclic compounds with kinase activities and uses thereof |
WO2017214269A1 (en) | 2016-06-08 | 2017-12-14 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
KR101932146B1 (en) | 2016-07-14 | 2018-12-24 | 주식회사 바이오웨이 | Novel Quinazolinone derivatives as PI3K inhibitors, and pharmaceutical composition comprising the same |
TW201825465A (en) | 2016-09-23 | 2018-07-16 | 美商基利科學股份有限公司 | Phosphatidylinositol 3-kinase inhibitors |
TW201815787A (en) | 2016-09-23 | 2018-05-01 | 美商基利科學股份有限公司 | Phosphatidylinositol 3-kinase inhibitors |
TW201813963A (en) | 2016-09-23 | 2018-04-16 | 美商基利科學股份有限公司 | Phosphatidylinositol 3-kinase inhibitors |
CN108003190B (en) * | 2017-12-27 | 2020-06-12 | 东南大学 | Preparation method of glufosinate-ammonium |
JP7450541B2 (en) | 2018-01-20 | 2024-03-15 | サンシャイン・レイク・ファーマ・カンパニー・リミテッド | Substituted aminopyrimidine compounds and methods of use |
CN110283174B (en) * | 2019-07-31 | 2021-07-23 | 安徽中医药大学 | PI3K delta inhibitor and application thereof |
CN111440173B (en) * | 2020-03-27 | 2021-05-14 | 山东大学 | Preparation method of PI3K inhibitor |
CN115304600B (en) * | 2022-09-29 | 2023-01-13 | 北京鑫开元医药科技有限公司 | mTOR inhibitor, preparation method and application |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI2223922T1 (en) * | 2000-04-25 | 2016-04-29 | Icos Corporation | Inhibitors of human phosphatidyl-inositol 3-kinase delta |
ES2605792T3 (en) * | 2004-05-13 | 2017-03-16 | Icos Corporation | Quinazolinone used as a human phosphatidylinositol 3-kinase delta inhibitor |
CA2569406A1 (en) * | 2004-06-04 | 2005-12-22 | Icos Corporation | Methods for treating mast cell disorders |
KR20100119745A (en) * | 2007-11-13 | 2010-11-10 | 이코스 코포레이션 | Inhibitors of human phosphatidyl-inositol 3-kinase delta |
KR101653842B1 (en) * | 2008-01-04 | 2016-09-02 | 인텔리카인, 엘엘씨 | Certain chemical entities, compositions and methods |
CN102838601A (en) * | 2011-06-24 | 2012-12-26 | 山东亨利医药科技有限责任公司 | Selective phosphatidylinositol-3 kinase delta inhibitor |
-
2013
- 2013-08-08 WO PCT/CN2013/000934 patent/WO2014023083A1/en active Application Filing
- 2013-08-08 CN CN201380041007.1A patent/CN104768952B/en active Active
- 2013-08-08 SG SG11201501173SA patent/SG11201501173SA/en unknown
- 2013-08-08 SG SG10202003090VA patent/SG10202003090VA/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN104768952B (en) | 2016-10-19 |
CN104768952A (en) | 2015-07-08 |
SG11201501173SA (en) | 2015-05-28 |
WO2014023083A1 (en) | 2014-02-13 |
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