SG10201913988XA - Method for the absolute quantification of naturally processed hla-restricted cancer peptides - Google Patents

Method for the absolute quantification of naturally processed hla-restricted cancer peptides

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Publication number
SG10201913988XA
SG10201913988XA SG10201913988XA SG10201913988XA SG10201913988XA SG 10201913988X A SG10201913988X A SG 10201913988XA SG 10201913988X A SG10201913988X A SG 10201913988XA SG 10201913988X A SG10201913988X A SG 10201913988XA SG 10201913988X A SG10201913988X A SG 10201913988XA
Authority
SG
Singapore
Prior art keywords
absolute quantification
naturally processed
cancer peptides
restricted cancer
processed hla
Prior art date
Application number
SG10201913988XA
Inventor
Toni Weinschenk
Julia Leibold
Original Assignee
Immatics Biotechnologies Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immatics Biotechnologies Gmbh filed Critical Immatics Biotechnologies Gmbh
Publication of SG10201913988XA publication Critical patent/SG10201913988XA/en

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56977HLA or MHC typing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70539MHC-molecules, e.g. HLA-molecules
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00Labels used in chemical analysis of biological material
    • G01N2458/15Non-radioactive isotope labels, e.g. for detection by mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2496/00Reference solutions for assays of biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00Chemical aspects of mass spectrometric analysis of biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
SG10201913988XA 2014-12-30 2015-12-15 Method for the absolute quantification of naturally processed hla-restricted cancer peptides SG10201913988XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462097994P 2014-12-30 2014-12-30
GBGB1423361.3A GB201423361D0 (en) 2014-12-30 2014-12-30 Method for the absolute Quantification of naturally processed HLA-Restricted cancer peptides

Publications (1)

Publication Number Publication Date
SG10201913988XA true SG10201913988XA (en) 2020-03-30

Family

ID=52471641

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201913988XA SG10201913988XA (en) 2014-12-30 2015-12-15 Method for the absolute quantification of naturally processed hla-restricted cancer peptides
SG11201703841VA SG11201703841VA (en) 2014-12-30 2015-12-15 Method for the absolute quantification of naturally processed hla-restricted cancer peptides

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201703841VA SG11201703841VA (en) 2014-12-30 2015-12-15 Method for the absolute quantification of naturally processed hla-restricted cancer peptides

Country Status (35)

Country Link
US (2) US10545154B2 (en)
EP (1) EP3241026B1 (en)
JP (1) JP6735741B2 (en)
KR (1) KR102336968B1 (en)
CN (1) CN107003322B (en)
AU (1) AU2015373584B2 (en)
BR (1) BR112017008212B1 (en)
CA (1) CA2972306C (en)
CL (1) CL2017001071A1 (en)
CO (1) CO2017004543A2 (en)
CR (1) CR20170297A (en)
CY (1) CY1124223T1 (en)
DK (1) DK3241026T3 (en)
EA (1) EA036328B1 (en)
ES (1) ES2871035T3 (en)
GB (1) GB201423361D0 (en)
HR (1) HRP20210811T1 (en)
HU (1) HUE054455T2 (en)
IL (1) IL250982B (en)
LT (1) LT3241026T (en)
MA (2) MA41287B1 (en)
MD (1) MD3241026T2 (en)
MX (1) MX2017008722A (en)
MY (1) MY190199A (en)
PE (1) PE20171136A1 (en)
PH (1) PH12017500483A1 (en)
PL (1) PL3241026T3 (en)
PT (1) PT3241026T (en)
RS (1) RS61914B1 (en)
SG (2) SG10201913988XA (en)
SI (1) SI3241026T1 (en)
TW (1) TWI632370B (en)
UA (1) UA122774C2 (en)
WO (1) WO2016107740A1 (en)
ZA (1) ZA201701646B (en)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201423361D0 (en) * 2014-12-30 2015-02-11 Immatics Biotechnologies Gmbh Method for the absolute Quantification of naturally processed HLA-Restricted cancer peptides
CR20210232A (en) * 2015-03-17 2022-06-24 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers
GB201513921D0 (en) 2015-08-05 2015-09-23 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers
EP4317432A3 (en) 2016-12-08 2024-04-17 Immatics Biotechnologies GmbH T cell receptors with improved pairing
DE102016123893A1 (en) 2016-12-08 2018-06-14 Immatics Biotechnologies Gmbh T cell receptors with improved binding
PE20200614A1 (en) 2017-07-14 2020-03-11 Immatics Biotechnologies Gmbh POLYPEPTIDE MOLECULE WITH ENHANCED DUAL SPECIFICITY
DE102017127984B4 (en) 2017-11-27 2019-12-05 Immatics US, Inc. Method for the propagation and activation of γδ T cells
SG11202007543TA (en) 2018-02-09 2020-09-29 Immatics Us Inc Methods for manufacturing t cells
DE102018107224A1 (en) 2018-02-21 2019-08-22 Immatics Biotechnologies Gmbh Peptides and combinations of peptides of non-canonical origin for use in immunotherapy against various cancers
KR20200027858A (en) * 2018-09-05 2020-03-13 에스케이하이닉스 주식회사 Memory controller and memory system having the same
TW202039535A (en) 2018-12-18 2020-11-01 德商英麥提克生物技術股份有限公司 Immunotherapy with b*08 restricted peptides and combination of peptides against cancers and related methods
US20200297768A1 (en) 2019-03-19 2020-09-24 Immatics US, Inc. Cd28 t cell cultures, compositions, and methods of using thereof
TW202110875A (en) 2019-05-27 2021-03-16 美商英麥提克斯股份有限公司 Viral vectors and use thereof in adoptive cellular therapy
US20200384028A1 (en) 2019-06-06 2020-12-10 Immatics Biotechnologies Gmbh Sorting with counter selection using sequence similar peptides
US20210032370A1 (en) 2019-08-02 2021-02-04 Immatics Biotechnologies Gmbh Recruiting agent further binding an mhc molecule
DE102019121007A1 (en) 2019-08-02 2021-02-04 Immatics Biotechnologies Gmbh Antigen binding proteins that specifically bind to MAGE-A
EP4010708A1 (en) 2019-08-09 2022-06-15 Immatics US, Inc. Methods for peptide mass spectrometry fragmentation prediction
US20210048442A1 (en) 2019-08-13 2021-02-18 Immatics Biotechnologies Gmbh Method for the characterization of peptide:mhc binding polypeptides
EP4110901A1 (en) 2020-02-24 2023-01-04 immatics US, Inc. Methods for expanding t cells for the treatment of cancer and related malignancies
DE102020111571A1 (en) 2020-03-11 2021-09-16 Immatics US, Inc. WPRE MUTANT CONSTRUCTS, COMPOSITIONS, AND RELATED PROCEDURES
DE102020106710A1 (en) 2020-03-11 2021-09-16 Immatics US, Inc. WPRE MUTANT CONSTRUCTS, COMPOSITIONS, AND RELATED PROCEDURES
US20220017636A1 (en) 2020-05-19 2022-01-20 Amgen Inc. Mageb2 binding constructs
US20220056411A1 (en) 2020-08-21 2022-02-24 Immatics US, Inc. Methods for isolating cd8+ selected t cells
DE102020125457A1 (en) 2020-09-29 2022-03-31 Immatics Biotechnologies Gmbh Amidated peptides and their deamidated counterparts presented by HLA-A*02 molecules for use in immunotherapy against various types of cancer
JP2024502034A (en) 2020-12-31 2024-01-17 イマティクス ユーエス,アイエヌシー. CD8 polypeptides, compositions, and methods of using them
CA3217739A1 (en) 2021-05-05 2022-11-10 Sebastian Bunk Bma031 antigen binding polypeptides
IL308257A (en) 2021-05-05 2024-01-01 Immatics Biotechnologies Gmbh Antigen binding proteins specifically binding prame
US20230024554A1 (en) 2021-06-28 2023-01-26 Immatics Biotechnologies Gmbh Method of characterizing the binding characteristics between a peptide of interest and mhc molecules
EP4113120A1 (en) 2021-06-28 2023-01-04 Immatics Biotechnologies GmbH Method of characterizing the binding characteristics between a peptide of interest and mhc molecules
TW202321277A (en) 2021-07-27 2023-06-01 德商英麥提克生物技術股份有限公司 Antigen binding proteins specifically binding ct45
WO2023025851A1 (en) 2021-08-24 2023-03-02 Immatics US, Inc. Selection of immune cells using peptide mhc complexes generated by conditional ligand exchange
WO2023044488A1 (en) 2021-09-20 2023-03-23 Immatics US, Inc. Monocyte depletion of t cells populations for t-cell therapy
US20230190806A1 (en) 2021-10-06 2023-06-22 Immatics Biotechnologies Gmbh Methods of treating metastatic lesions and compositions thereof
WO2023081925A1 (en) 2021-11-08 2023-05-11 Immatics Biotechnologies Gmbh Adoptive cell therapy combination treatment and compositions thereof
WO2023212655A1 (en) 2022-04-28 2023-11-02 Immatics US, Inc. Il-12 polypeptides, il-15 polypeptides, il-18 polypeptides, cd8 polypeptides, compositions, and methods of using thereof
WO2023212691A1 (en) 2022-04-28 2023-11-02 Immatics US, Inc. DOMINANT NEGATIVE TGFβ RECEPTOR POLYPEPTIDES, CD8 POLYPEPTIDES, CELLS, COMPOSITIONS, AND METHODS OF USING THEREOF
WO2023212697A1 (en) 2022-04-28 2023-11-02 Immatics US, Inc. Membrane-bound il-15, cd8 polypeptides, cells, compositions, and methods of using thereof
WO2023215825A1 (en) 2022-05-05 2023-11-09 Immatics US, Inc. Methods for improving t cell efficacy

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4290003B2 (en) 2001-09-14 2009-07-01 エレクトロフォレティクス リミテッド Mass label
US20050221350A1 (en) * 2002-05-29 2005-10-06 Toni Weinschenk Method for identifying immunoreactive peptides
DE10225139A1 (en) 2002-05-29 2004-02-26 Immatics Biotechnologies Gmbh Methods for the identification of immunoreactive peptides
US6644103B1 (en) 2002-10-24 2003-11-11 Simmonds Precision Products, Inc. Method and apparatus for detecting a dry/wet state of a thermistor bead
AU2003277610A1 (en) * 2002-11-08 2004-06-07 Shuichi Hanada Method of examining cancer cells and reagent therefor
JP2007519910A (en) 2004-01-28 2007-07-19 イマティクス バイオテクノロジーズ ゲーエムベーハー Methods for identifying and quantifying tumor-related peptides
JP2008043332A (en) * 2006-08-17 2008-02-28 Panomics Inc Quantitative determination of nucleic acid from tissue slide
ES2536465T3 (en) * 2008-10-01 2015-05-25 Immatics Biotechnologies Gmbh Composition of tumor-associated and cancer-related peptides for the treatment of glioblastoma (GBM) and other cancers
GB201004551D0 (en) * 2010-03-19 2010-05-05 Immatics Biotechnologies Gmbh NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer
GB201006360D0 (en) * 2010-04-16 2010-06-02 Immatics Biotechnologies Gmbh Method for differentially quantifying naturally processed HLA-restricted peptides for cancer, autoimmune and infectious diseases immunotherapy development
US20140051092A1 (en) 2011-04-15 2014-02-20 Micromass Uk Limited Method And Apparatus For The Analysis Of Biological Samples
WO2012178030A2 (en) 2011-06-24 2012-12-27 Applied Isotope Technologies, Inc. Accurate measurement of glutathione for disease diagnosis and drug metabolite screening
US10077171B2 (en) * 2012-10-17 2018-09-18 Grant C. Chustz Safety barrier for vehicles and cranes
GB201423361D0 (en) * 2014-12-30 2015-02-11 Immatics Biotechnologies Gmbh Method for the absolute Quantification of naturally processed HLA-Restricted cancer peptides
DE102016115246C5 (en) * 2016-08-17 2018-12-20 Immatics Biotechnologies Gmbh NEW T-CELL RECEPTORS AND THEIR USE IN IMMUNOTHERAPY
WO2019086665A1 (en) * 2017-11-06 2019-05-09 Immatics Biotechnologies Gmbh Novel engineered t cell receptors and immune therapy using the same

Also Published As

Publication number Publication date
MX2017008722A (en) 2017-10-18
MA40137B1 (en) 2019-05-31
EA201791148A1 (en) 2017-11-30
PL3241026T3 (en) 2021-10-25
JP6735741B2 (en) 2020-08-05
AU2015373584B2 (en) 2022-02-24
PE20171136A1 (en) 2017-08-09
MD3241026T2 (en) 2021-07-31
US20160187351A1 (en) 2016-06-30
US11988669B2 (en) 2024-05-21
LT3241026T (en) 2021-05-25
US20200103408A1 (en) 2020-04-02
AU2015373584A1 (en) 2017-04-20
SI3241026T1 (en) 2021-08-31
IL250982A0 (en) 2017-04-30
HRP20210811T1 (en) 2021-09-03
CO2017004543A2 (en) 2017-09-29
RS61914B1 (en) 2021-06-30
US10545154B2 (en) 2020-01-28
KR102336968B1 (en) 2021-12-08
PT3241026T (en) 2021-05-25
BR112017008212A2 (en) 2017-12-26
CA2972306A1 (en) 2016-07-07
WO2016107740A1 (en) 2016-07-07
CN107003322A (en) 2017-08-01
EP3241026B1 (en) 2021-04-14
MY190199A (en) 2022-04-04
CR20170297A (en) 2017-10-19
UA122774C2 (en) 2021-01-06
MA41287B1 (en) 2021-07-29
ES2871035T3 (en) 2021-10-28
CN107003322B (en) 2019-08-30
TW201631320A (en) 2016-09-01
BR112017008212B1 (en) 2023-11-28
JP2018500004A (en) 2018-01-11
HUE054455T2 (en) 2021-09-28
TWI632370B (en) 2018-08-11
MA41287A (en) 2017-11-08
CY1124223T1 (en) 2022-05-27
EA036328B1 (en) 2020-10-27
DK3241026T3 (en) 2021-05-10
KR20170099914A (en) 2017-09-01
EP3241026A1 (en) 2017-11-08
SG11201703841VA (en) 2017-07-28
CA2972306C (en) 2021-02-16
ZA201701646B (en) 2018-05-30
MA40137A1 (en) 2018-03-30
GB201423361D0 (en) 2015-02-11
PH12017500483A1 (en) 2017-08-07
CL2017001071A1 (en) 2017-12-22
IL250982B (en) 2020-08-31

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