SG10201913521TA - Methods for enzymatic peptide ligation - Google Patents

Methods for enzymatic peptide ligation

Info

Publication number
SG10201913521TA
SG10201913521TA SG10201913521TA SG10201913521TA SG10201913521TA SG 10201913521T A SG10201913521T A SG 10201913521TA SG 10201913521T A SG10201913521T A SG 10201913521TA SG 10201913521T A SG10201913521T A SG 10201913521TA SG 10201913521T A SG10201913521T A SG 10201913521TA
Authority
SG
Singapore
Prior art keywords
methods
peptide ligation
enzymatic peptide
enzymatic
ligation
Prior art date
Application number
SG10201913521TA
Inventor
Bin Wu
Renliang Yang
Yee Hwa Wong
Julien Lescar
Chuan Fa Liu
James P Tam
Kien Truc Giang Nguyen
Ziqi Long
Original Assignee
Univ Nanyang Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Nanyang Tech filed Critical Univ Nanyang Tech
Publication of SG10201913521TA publication Critical patent/SG10201913521TA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
SG10201913521TA 2016-09-23 2017-09-12 Methods for enzymatic peptide ligation SG10201913521TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SG10201607951V 2016-09-23

Publications (1)

Publication Number Publication Date
SG10201913521TA true SG10201913521TA (en) 2020-03-30

Family

ID=61689245

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10201913521TA SG10201913521TA (en) 2016-09-23 2017-09-12 Methods for enzymatic peptide ligation

Country Status (5)

Country Link
US (2) US11795488B2 (en)
EP (1) EP3515931B1 (en)
CN (1) CN109790205B (en)
SG (1) SG10201913521TA (en)
WO (1) WO2018056899A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111117977B (en) * 2020-01-06 2021-09-10 广州英赞生物科技有限公司 Recombinant polypeptide linked zymogen, preparation method, activation method and application thereof
CN111951884B (en) * 2020-07-10 2022-03-22 中南大学 Identification method of flexible amino acid key on protein small molecule binding pocket
EP4291674A1 (en) * 2021-02-10 2023-12-20 Nanyang Technological University Methods for (poly) peptide tandem ligation and cyclization
WO2023191726A1 (en) * 2022-03-31 2023-10-05 Nanyang Technological University Improving the efficiency of pal-catalyzed protein ligation by a cascade enzymatic scheme

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6855871B2 (en) * 2000-08-21 2005-02-15 Pioneer Hi-Bred International, Inc. Methods of increasing polypeptide accumulation in plants
US9796764B2 (en) * 2011-03-23 2017-10-24 The University Of Queensland Cyclotide genes in the fabaceae plant family
CN103044521B (en) * 2012-12-26 2014-11-05 亚飞（上海）生物医药科技有限公司 Aspartase-targeted activated adriamycin derivative as well as preparation method and application thereof
US10590407B2 (en) 2014-04-24 2020-03-17 Nanyang Technological University Asx-specific protein ligase
JP2019500879A (en) * 2015-09-25 2019-01-17 ヘキシマ リミテッド Peptide generation
CN108289428A (en) 2015-09-30 2018-07-17 赫希玛有限公司 A kind of method

Also Published As

Publication number Publication date
US20230128192A1 (en) 2023-04-27
EP3515931C0 (en) 2024-05-01
EP3515931B1 (en) 2024-05-01
US11795488B2 (en) 2023-10-24
CN109790205B (en) 2024-01-16
US20190218586A1 (en) 2019-07-18
WO2018056899A1 (en) 2018-03-29
EP3515931A1 (en) 2019-07-31
CN109790205A (en) 2019-05-21
EP3515931A4 (en) 2020-04-22

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