SG10201900025UA - Pyridines, pyrimidines, and pyrazines, as btk inhibitors and uses thereof - Google Patents
Pyridines, pyrimidines, and pyrazines, as btk inhibitors and uses thereofInfo
- Publication number
- SG10201900025UA SG10201900025UA SG10201900025UA SG10201900025UA SG10201900025UA SG 10201900025U A SG10201900025U A SG 10201900025UA SG 10201900025U A SG10201900025U A SG 10201900025UA SG 10201900025U A SG10201900025U A SG 10201900025UA SG 10201900025U A SG10201900025U A SG 10201900025UA
- Authority
- SG
- Singapore
- Prior art keywords
- pyrazines
- pyridines
- pyrimidines
- btk inhibitors
- btk
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
PYRIDINES, PYRIMIDINES, AND PYRAZINES, AS BTK INHIBITORS AND USES THEREOF The present invention relates to pyridine, pyrimidine, and pyrazene compounds, and pharmaceutically acceptable compositions thereof, useful as BTK inhibitors.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361860401P | 2013-07-31 | 2013-07-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201900025UA true SG10201900025UA (en) | 2019-02-27 |
Family
ID=51303133
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201600159TA SG11201600159TA (en) | 2013-07-31 | 2014-07-30 | Pyridines, pyrimidines, and pyrazines, as btk inhibitors and uses thereof |
SG10201900025UA SG10201900025UA (en) | 2013-07-31 | 2014-07-30 | Pyridines, pyrimidines, and pyrazines, as btk inhibitors and uses thereof |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201600159TA SG11201600159TA (en) | 2013-07-31 | 2014-07-30 | Pyridines, pyrimidines, and pyrazines, as btk inhibitors and uses thereof |
Country Status (24)
Country | Link |
---|---|
US (2) | US9738648B2 (en) |
EP (1) | EP3049417B1 (en) |
JP (1) | JP6612751B2 (en) |
KR (1) | KR20160036053A (en) |
CN (1) | CN105814057B (en) |
AU (1) | AU2014296261B2 (en) |
BR (1) | BR112016001600A8 (en) |
CA (1) | CA2918242C (en) |
DK (1) | DK3049417T3 (en) |
ES (1) | ES2706150T3 (en) |
HR (1) | HRP20190054T1 (en) |
HU (1) | HUE042111T2 (en) |
IL (1) | IL243844B (en) |
LT (1) | LT3049417T (en) |
MX (1) | MX367085B (en) |
NZ (1) | NZ715838A (en) |
PL (1) | PL3049417T3 (en) |
PT (1) | PT3049417T (en) |
RS (1) | RS58361B1 (en) |
RU (1) | RU2712220C2 (en) |
SG (2) | SG11201600159TA (en) |
SI (1) | SI3049417T1 (en) |
WO (1) | WO2015017502A1 (en) |
ZA (1) | ZA201600564B (en) |
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