SG10201810692VA - Process to prepare 3-methyl-2-nitrobenzoic acid by air oxidation - Google Patents

Process to prepare 3-methyl-2-nitrobenzoic acid by air oxidation

Info

Publication number
SG10201810692VA
SG10201810692VA SG10201810692VA SG10201810692VA SG10201810692VA SG 10201810692V A SG10201810692V A SG 10201810692VA SG 10201810692V A SG10201810692V A SG 10201810692VA SG 10201810692V A SG10201810692V A SG 10201810692VA SG 10201810692V A SG10201810692V A SG 10201810692VA
Authority
SG
Singapore
Prior art keywords
methyl
nitrobenzoic acid
prepare
air oxidation
disclosed
Prior art date
Application number
SG10201810692VA
Inventor
Stephen Ernest Jacobson
Donald J Dumas
Rupert Spence
Venkateswara Rao Surisetty
Sarah May Crawford
Original Assignee
Fmc Agro Singapore Pte Ltd
Fmc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Agro Singapore Pte Ltd, Fmc Corp filed Critical Fmc Agro Singapore Pte Ltd
Publication of SG10201810692VA publication Critical patent/SG10201810692VA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/14—Preparation of carboxylic acid nitriles by reaction of cyanides with halogen-containing compounds with replacement of halogen atoms by cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/57—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and carboxyl groups, other than cyano groups, bound to the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)

Abstract

A method for preparing 3-methyl-2-nitrobenzoic acid is disclosed wherein 1,3-dimethyl- 2-nitrobenzene is combined with an oxidation catalayst in the presence of an oxygen source and an initiator, provided that less than 99% of the 1,3-dimethyl-2-nitrobenzene is oxidized. A method for preparing compounds of Formula 7 and Formula 11 is also disclosed 5 wherein the method is characterized by using 3-methyl-2-nitrobenzoic acid as prepared by the method disclosed above, wherein R 1 is C 1–C7 alkyl, C 3–C6 cycloalkyl or C 4–C7 alkylcycloalkyl. 10 NO FIGURE
SG10201810692VA 2014-05-29 2015-05-29 Process to prepare 3-methyl-2-nitrobenzoic acid by air oxidation SG10201810692VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462004459P 2014-05-29 2014-05-29
US201462027275P 2014-07-22 2014-07-22

Publications (1)

Publication Number Publication Date
SG10201810692VA true SG10201810692VA (en) 2018-12-28

Family

ID=53284682

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201810692VA SG10201810692VA (en) 2014-05-29 2015-05-29 Process to prepare 3-methyl-2-nitrobenzoic acid by air oxidation
SG11201609547SA SG11201609547SA (en) 2014-05-29 2015-05-29 Process to prepare 3-methyl-2-nitrobenzoic acid by air oxidation

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201609547SA SG11201609547SA (en) 2014-05-29 2015-05-29 Process to prepare 3-methyl-2-nitrobenzoic acid by air oxidation

Country Status (16)

Country Link
US (2) US9828328B2 (en)
EP (1) EP3148962B1 (en)
JP (1) JP6611735B2 (en)
KR (2) KR20170013249A (en)
CN (2) CN106458843A (en)
AU (1) AU2015266819B2 (en)
BR (1) BR112016027556B1 (en)
HU (1) HUE050832T2 (en)
IL (1) IL248796B (en)
MX (1) MX2016015454A (en)
PL (1) PL3148962T3 (en)
RU (1) RU2689126C2 (en)
SG (2) SG10201810692VA (en)
TW (1) TWI678354B (en)
WO (1) WO2015184229A1 (en)
ZA (1) ZA201607811B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI678354B (en) * 2014-05-29 2019-12-01 新加坡商艾佛艾姆希農業新加坡有限公司 Process to prepare 3-methyl-2-nitrobenzoic acid by air oxidation
CN114560773B (en) * 2022-02-14 2023-07-28 南昌大学 Synthesis method of 2-nitro-3-methylbenzoic acid
CN114560772B (en) * 2022-02-14 2023-07-28 南昌大学 Synthesis method of 3-methyl-2-nitrobenzoic acid
TW202346260A (en) * 2022-04-14 2023-12-01 美商富曼西公司 Methods for the preparation of 5-chloro-2-((ethoxycarbonyl)amino)-3-methylbenzoic acid

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JP2000290235A (en) * 1999-04-07 2000-10-17 Fuso Chemical Co Ltd Production of 3-nitro-2-methylbenzoic acid
JP2001011026A (en) * 1999-07-02 2001-01-16 Fuso Chemical Co Ltd Production of 3-methyl-4-nitrobenzoic acid
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WO2004014873A1 (en) * 2002-08-09 2004-02-19 Kyorin Pharmaceutical Co., Ltd. 4-substituted quinazoline-8-carboxyamide derivative and pharmaceutically acceptable addition salt thereof
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TWI363756B (en) 2004-12-07 2012-05-11 Du Pont Method for preparing n-phenylpyrazole-1-carboxamides
WO2006080311A1 (en) * 2005-01-25 2006-08-03 Ishihara Sangyo Kaisha, Ltd. Anthranilamide compound, method for producing same and pest control agent containing same
JP2006232814A (en) * 2005-01-25 2006-09-07 Ishihara Sangyo Kaisha Ltd Anthranilamide-based compound, method for producing the same and pest control agent containing the same
JP2009062277A (en) * 2005-12-27 2009-03-26 Nippon Soda Co Ltd Benzisothiazoline compound and pest control agent
CA2656357C (en) 2006-07-19 2014-05-06 E.I. Du Pont De Nemours And Company Process for making 3-substituted 2-amino-5-halobenzamides
CN100434175C (en) * 2006-10-17 2008-11-19 郑州大学 Catalyst and its use for synthesizing 4-nitro-3-methyl benzoic acid
TWI395728B (en) 2006-12-06 2013-05-11 Du Pont Process for preparing 2-amino-5-cyanobenzoic acid derivatives
TWI415827B (en) 2006-12-21 2013-11-21 Du Pont Process for preparing 2-amino-5-cyanobenzoic acid derivatives
TWI430980B (en) 2007-06-29 2014-03-21 Du Pont Process for preparing 2-amino-5-cyanobenzoic acid derivatives
KR20100098382A (en) 2007-11-08 2010-09-06 이 아이 듀폰 디 네모아 앤드 캄파니 Process for preparing 2-amino-5-cyanobenzoic acid derivatives
TWI432421B (en) * 2007-12-19 2014-04-01 Du Pont Process for preparing 2-amino-5-cyanobenzoic acid derivatives
TWI431000B (en) * 2008-03-05 2014-03-21 Du Pont Process for preparing 2-amino-5-cyanobenzoic acid derivatives
DE102010030629A1 (en) 2010-06-29 2011-12-29 Robert Bosch Gmbh Speed sensor, vehicle dynamics control device, control device and systems with such devices and method for receiving data via a radio station by the control unit
EP2668153B1 (en) * 2011-01-28 2015-03-04 E.I. Du Pont De Nemours And Company Method for preparing 2-aminobenzamide derivatives
CN103396467B (en) * 2013-08-05 2015-01-28 上海杏灵科技药业股份有限公司 Preparation method of sterol compound
TWI678354B (en) * 2014-05-29 2019-12-01 新加坡商艾佛艾姆希農業新加坡有限公司 Process to prepare 3-methyl-2-nitrobenzoic acid by air oxidation

Also Published As

Publication number Publication date
ZA201607811B (en) 2018-05-30
JP6611735B2 (en) 2019-11-27
US10155718B2 (en) 2018-12-18
TW201602058A (en) 2016-01-16
BR112016027556B1 (en) 2021-08-10
RU2016151919A (en) 2018-07-02
US20170197907A1 (en) 2017-07-13
IL248796B (en) 2020-02-27
CN116283596A (en) 2023-06-23
IL248796A0 (en) 2017-01-31
KR20170013249A (en) 2017-02-06
SG11201609547SA (en) 2016-12-29
BR112016027556A2 (en) 2017-08-15
PL3148962T3 (en) 2020-12-28
RU2016151919A3 (en) 2018-12-03
HUE050832T2 (en) 2021-01-28
AU2015266819B2 (en) 2019-04-04
TWI678354B (en) 2019-12-01
RU2689126C2 (en) 2019-05-24
KR20230052989A (en) 2023-04-20
WO2015184229A1 (en) 2015-12-03
AU2015266819A1 (en) 2016-11-24
EP3148962B1 (en) 2020-05-13
MX2016015454A (en) 2017-03-23
US9828328B2 (en) 2017-11-28
JP2017516808A (en) 2017-06-22
US20180072653A1 (en) 2018-03-15
CN106458843A (en) 2017-02-22
EP3148962A1 (en) 2017-04-05

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