SG10201808165YA - Sample analysis for mass cytometry - Google Patents

Sample analysis for mass cytometry

Info

Publication number
SG10201808165YA
SG10201808165YA SG10201808165YA SG10201808165YA SG10201808165YA SG 10201808165Y A SG10201808165Y A SG 10201808165YA SG 10201808165Y A SG10201808165Y A SG 10201808165YA SG 10201808165Y A SG10201808165Y A SG 10201808165YA SG 10201808165Y A SG10201808165Y A SG 10201808165YA
Authority
SG
Singapore
Prior art keywords
mass cytometry
sample analysis
analysis
icp
devices
Prior art date
Application number
SG10201808165YA
Inventor
Alexandre Loboda
Original Assignee
Fluidigm Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fluidigm Canada Inc filed Critical Fluidigm Canada Inc
Publication of SG10201808165YA publication Critical patent/SG10201808165YA/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1404—Fluid conditioning in flow cytometers, e.g. flow cells; Supply; Control of flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1434—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
    • G01N15/1436—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement the optical arrangement forming an integrated apparatus with the sample container, e.g. a flow cell
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0459—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for solid samples
    • H01J49/0463—Desorption by laser or particle beam, followed by ionisation as a separate step
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/105—Ion sources; Ion guns using high-frequency excitation, e.g. microwave excitation, Inductively Coupled Plasma [ICP]
    • G01N15/01—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers

Abstract

SAMPLE ANALYSIS FOR MASS CYTOMETRY The invention relates to methods and devices for analysis of samples using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). The invention provides methods and devices in which individual ablation plumes are distinctively captured and transferred to the ICP, followed by analysis by mass cytometry. FIG. 1
SG10201808165YA 2013-04-17 2014-04-17 Sample analysis for mass cytometry SG10201808165YA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361812893P 2013-04-17 2013-04-17

Publications (1)

Publication Number Publication Date
SG10201808165YA true SG10201808165YA (en) 2018-10-30

Family

ID=51730644

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201808165YA SG10201808165YA (en) 2013-04-17 2014-04-17 Sample analysis for mass cytometry
SG11201504874QA SG11201504874QA (en) 2013-04-17 2014-04-17 Sample analysis for mass cytometry

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201504874QA SG11201504874QA (en) 2013-04-17 2014-04-17 Sample analysis for mass cytometry

Country Status (8)

Country Link
US (6) US9589779B2 (en)
EP (2) EP3690923A1 (en)
JP (1) JP6230693B2 (en)
CN (1) CN105190829B (en)
CA (2) CA2895360C (en)
RU (1) RU2637795C2 (en)
SG (2) SG10201808165YA (en)
WO (1) WO2014169394A1 (en)

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Also Published As

Publication number Publication date
US20190271630A1 (en) 2019-09-05
US11630050B2 (en) 2023-04-18
EP2987177B1 (en) 2020-01-08
US10241023B2 (en) 2019-03-26
SG11201504874QA (en) 2015-07-30
EP2987177A1 (en) 2016-02-24
US20160056031A1 (en) 2016-02-25
CA2895360A1 (en) 2014-10-23
EP2987177A4 (en) 2016-11-30
US10705006B2 (en) 2020-07-07
CA3191952A1 (en) 2014-10-23
EP3690923A1 (en) 2020-08-05
CA2895360C (en) 2023-05-02
JP2016522887A (en) 2016-08-04
US20170248507A1 (en) 2017-08-31
US9589779B2 (en) 2017-03-07
RU2015123440A (en) 2017-05-22
JP6230693B2 (en) 2017-11-15
CN105190829B (en) 2018-04-03
US20220178809A1 (en) 2022-06-09
US11099116B2 (en) 2021-08-24
US9952132B2 (en) 2018-04-24
CN105190829A (en) 2015-12-23
RU2637795C2 (en) 2017-12-07
US20200408662A1 (en) 2020-12-31
US20180306695A1 (en) 2018-10-25
WO2014169394A1 (en) 2014-10-23

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