SG10201800309SA - Adrenomedullin to guide therapy of blood pressure decline - Google Patents
Adrenomedullin to guide therapy of blood pressure declineInfo
- Publication number
- SG10201800309SA SG10201800309SA SG10201800309SA SG10201800309SA SG10201800309SA SG 10201800309S A SG10201800309S A SG 10201800309SA SG 10201800309S A SG10201800309S A SG 10201800309SA SG 10201800309S A SG10201800309S A SG 10201800309SA SG 10201800309S A SG10201800309S A SG 10201800309SA
- Authority
- SG
- Singapore
- Prior art keywords
- adrenomedullin
- blood pressure
- pressure decline
- guide therapy
- therapy
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/26—Infectious diseases, e.g. generalised sepsis
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13160265 | 2013-03-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201800309SA true SG10201800309SA (en) | 2018-02-27 |
Family
ID=47901848
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201507774YA SG11201507774YA (en) | 2013-03-20 | 2014-03-19 | Adrenomedullin to guide therapy of blood pressure decline |
SG10201800309SA SG10201800309SA (en) | 2013-03-20 | 2014-03-19 | Adrenomedullin to guide therapy of blood pressure decline |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201507774YA SG11201507774YA (en) | 2013-03-20 | 2014-03-19 | Adrenomedullin to guide therapy of blood pressure decline |
Country Status (11)
Country | Link |
---|---|
US (2) | US10598674B2 (en) |
EP (1) | EP2976646B1 (en) |
JP (3) | JP6259905B2 (en) |
CN (2) | CN105102985B (en) |
CA (1) | CA2907467A1 (en) |
DK (1) | DK2976646T3 (en) |
ES (1) | ES2830036T3 (en) |
HK (2) | HK1216264A1 (en) |
RU (1) | RU2673455C2 (en) |
SG (2) | SG11201507774YA (en) |
WO (1) | WO2014147153A1 (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017089474A1 (en) * | 2015-11-27 | 2017-06-01 | Brahms Gmbh | MR-proADM AS MARKER FOR THE EXTRACELLULAR VOLUME STATUS OF A SUBJECT |
EP3482208B1 (en) * | 2016-07-08 | 2023-04-12 | SphingoTec GmbH | Adrenomedullin for assessing congestion in a subject with acute heart failure |
EP3309550A1 (en) * | 2016-10-12 | 2018-04-18 | sphingotec GmbH | Method for the detection of apolipoprotein e4 |
JP6855118B2 (en) * | 2017-03-14 | 2021-04-07 | 東ソー株式会社 | Methods and measurement reagents that provide information for assessing the quality of general condition |
US11578112B2 (en) * | 2017-03-29 | 2023-02-14 | University Of Miyazaki | Long-acting adrenomedullin derivative conjugated with Fc region of immunoglobulin |
CN107194129B (en) * | 2017-06-30 | 2019-08-06 | 江南大学 | A method of using the modified ADM1 model analysis kitchen garbage methane phase of lactic acid |
EP3438668A1 (en) | 2017-08-04 | 2019-02-06 | B.R.A.H.M.S GmbH | Diagnosis and risk stratification of fungal infections |
US20200271667A1 (en) * | 2017-09-13 | 2020-08-27 | B.R.A.H.M.S Gmbh | Method for guidance of fluid therapy based on proadrenomedullin |
US20200264199A1 (en) * | 2017-09-13 | 2020-08-20 | B.R.A.H.M.S Gmbh | Pct and pro-adm as markers for monitoring antibiotic treatment |
EP3682247B1 (en) | 2017-09-13 | 2022-02-09 | B.R.A.H.M.S GmbH | Proadrenomedullin as a marker for abnormal platelet levels |
EP3682236A1 (en) * | 2017-09-13 | 2020-07-22 | B.R.A.H.M.S GmbH | Proadrenomedullin as indicator for renal replacement therapy in critically ill patients |
AU2018335438A1 (en) * | 2017-09-25 | 2020-04-09 | Adrenomed Ag | Anti-adrenomedullin (ADM) binder for use in therapy or prevention of symptoms of illness |
MX2020004072A (en) * | 2017-10-18 | 2020-07-28 | Adrenomed Ag | Therapy monitoring under treatment with an anti-adrenomedullin (adm) binder. |
EP3502706A1 (en) * | 2017-12-20 | 2019-06-26 | B.R.A.H.M.S GmbH | Workflow for risk assessment and patient management using procalcitonin and midregional-proadrenomedullin |
US20210109118A1 (en) * | 2017-12-20 | 2021-04-15 | B.R.A.H.M.S Gmbh | Antibiotic therapy guidance based on pro-adm |
EP3578989A1 (en) * | 2018-06-06 | 2019-12-11 | B.R.A.H.M.S GmbH | Pro-adm for prognosis of trauma-related complications in polytrauma patients |
CA3119792A1 (en) * | 2018-11-15 | 2020-05-22 | Ferring B.V. | Compounds, compositions and methods for treating sepsis |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
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US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
GB8519425D0 (en) | 1985-08-01 | 1985-09-04 | Ici Plc | Amine production |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
EP1690935A3 (en) | 1990-01-12 | 2008-07-30 | Abgenix, Inc. | Generation of xenogeneic antibodies |
US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
AU665190B2 (en) | 1990-07-10 | 1995-12-21 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
WO1993012227A1 (en) | 1991-12-17 | 1993-06-24 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
JP2774769B2 (en) | 1993-04-26 | 1998-07-09 | 賢治 寒川 | Adrenomedullin |
US6818418B1 (en) | 1998-12-10 | 2004-11-16 | Compound Therapeutics, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
ATE490969T1 (en) | 2001-08-30 | 2010-12-15 | Biorexis Pharmaceutical Corp | MODIFIED TRANSFERRIN FUSION PROTEINS |
PT2311432E (en) | 2002-06-07 | 2015-02-09 | Dyax Corp | Modified kunitz domain polypeptides and their use for reducing ischemia or the onset of a systemic inflammatory response associated with a surgical procedure |
DE10316583A1 (en) * | 2003-04-10 | 2004-10-28 | B.R.A.H.M.S Aktiengesellschaft | Determination of a mid-regional proadrenomedullin partial peptide in biological fluids for diagnostic purposes, as well as immunoassays for carrying out such a determination |
US20050148029A1 (en) * | 2003-09-29 | 2005-07-07 | Biosite, Inc. | Methods and compositions for determining treatment regimens in systemic inflammatory response syndromes |
AU2004284090A1 (en) | 2003-10-24 | 2005-05-06 | Avidia, Inc. | LDL receptor class A and EGF domain monomers and multimers |
US20100028995A1 (en) | 2004-02-23 | 2010-02-04 | Anaphore, Inc. | Tetranectin Trimerizing Polypeptides |
US8278262B2 (en) | 2004-09-21 | 2012-10-02 | Biontech Ag | Use of microproteins as tryptase inhibitors |
US20070092911A1 (en) * | 2005-10-03 | 2007-04-26 | Buechler Kenneth F | Methods and compositions for diagnosis and /or prognosis in systemic inflammatory response syndromes |
US8906857B2 (en) * | 2005-12-01 | 2014-12-09 | B.R.A.H.M.S. Gmbh | Methods for the diagnosis and treatment of critically ill patients with endothelin, endothelin agonists and adrenomedullin antagonists |
DE102006060112A1 (en) * | 2006-12-20 | 2008-06-26 | Brahms Aktiengesellschaft | Diagnosis and risk stratification using the new marker CT-proADM |
WO2009009907A1 (en) * | 2007-07-18 | 2009-01-22 | The University Of British Columbia | Use of vasopressin-receptor agonists for the treatment of septic shock |
ES2373832T3 (en) | 2007-12-19 | 2012-02-09 | Affibody Ab | POLYPEPTIDE DERIVED FROM PROTEIN A AND ABLE TO JOIN PDGF. |
WO2009150171A1 (en) * | 2008-06-10 | 2009-12-17 | Profos Ag | Method of treatment of inflammatory diseases |
ES2836948T3 (en) | 2008-11-03 | 2021-06-28 | Molecular Partners Ag | Binding proteins that inhibit VEGF-A receptor interaction |
EP2470556B1 (en) | 2009-08-27 | 2018-05-30 | Covagen AG | Il-17 binding compounds and medical uses thereof |
ES2441803T3 (en) | 2009-12-14 | 2014-02-06 | Scil Proteins Gmbh | A method to identify modified heteromultimer ubicuitin proteins capable of binding ligands |
PT2580236T (en) | 2010-06-08 | 2019-05-30 | Astrazeneca Ab | Tear lipocalin muteins binding il-4 r alpha |
BR112012032406A2 (en) * | 2010-06-18 | 2016-10-25 | Cezanne S A S | markers for prognosis and risk assessment of pregnancy-induced hypertension and preeclampsia |
-
2014
- 2014-03-19 CA CA2907467A patent/CA2907467A1/en active Pending
- 2014-03-19 RU RU2015144699A patent/RU2673455C2/en active
- 2014-03-19 JP JP2016504582A patent/JP6259905B2/en active Active
- 2014-03-19 SG SG11201507774YA patent/SG11201507774YA/en unknown
- 2014-03-19 WO PCT/EP2014/055554 patent/WO2014147153A1/en active Application Filing
- 2014-03-19 EP EP14711741.0A patent/EP2976646B1/en active Active
- 2014-03-19 DK DK14711741.0T patent/DK2976646T3/en active
- 2014-03-19 ES ES14711741T patent/ES2830036T3/en active Active
- 2014-03-19 CN CN201480010451.1A patent/CN105102985B/en active Active
- 2014-03-19 SG SG10201800309SA patent/SG10201800309SA/en unknown
- 2014-03-19 CN CN201810035720.XA patent/CN108362885B/en active Active
- 2014-03-19 US US14/778,114 patent/US10598674B2/en active Active
-
2016
- 2016-04-13 HK HK16104224.2A patent/HK1216264A1/en unknown
-
2017
- 2017-12-11 JP JP2017236881A patent/JP2018059947A/en not_active Ceased
-
2019
- 2019-01-17 HK HK19100872.2A patent/HK1258520A1/en unknown
- 2019-12-25 JP JP2019234773A patent/JP6820399B2/en active Active
-
2020
- 2020-02-04 US US16/781,226 patent/US20200249246A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP6820399B2 (en) | 2021-01-27 |
WO2014147153A1 (en) | 2014-09-25 |
RU2673455C2 (en) | 2018-11-27 |
CN108362885B (en) | 2021-05-14 |
JP2020073896A (en) | 2020-05-14 |
EP2976646A1 (en) | 2016-01-27 |
HK1216264A1 (en) | 2016-10-28 |
HK1258520A1 (en) | 2019-11-15 |
RU2015144699A (en) | 2017-04-28 |
EP2976646B1 (en) | 2020-08-19 |
SG11201507774YA (en) | 2015-10-29 |
ES2830036T3 (en) | 2021-06-02 |
US20200249246A1 (en) | 2020-08-06 |
CA2907467A1 (en) | 2014-09-25 |
JP2018059947A (en) | 2018-04-12 |
CN108362885A (en) | 2018-08-03 |
DK2976646T3 (en) | 2020-11-16 |
US10598674B2 (en) | 2020-03-24 |
CN105102985A (en) | 2015-11-25 |
JP2016521351A (en) | 2016-07-21 |
US20170010286A1 (en) | 2017-01-12 |
JP6259905B2 (en) | 2018-01-10 |
CN105102985B (en) | 2018-05-18 |
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