SG10201710928PA - Ocular formulations for drug-delivery to the posterior segment of the eye - Google Patents

Ocular formulations for drug-delivery to the posterior segment of the eye

Info

Publication number
SG10201710928PA
SG10201710928PA SG10201710928PA SG10201710928PA SG10201710928PA SG 10201710928P A SG10201710928P A SG 10201710928PA SG 10201710928P A SG10201710928P A SG 10201710928PA SG 10201710928P A SG10201710928P A SG 10201710928PA SG 10201710928P A SG10201710928P A SG 10201710928PA
Authority
SG
Singapore
Prior art keywords
eye
drug
delivery
posterior segment
ocular formulations
Prior art date
Application number
SG10201710928PA
Inventor
David P Bingaman
Paul G Chaney
Martin B Wax
Original Assignee
Panoptica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panoptica Inc filed Critical Panoptica Inc
Publication of SG10201710928PA publication Critical patent/SG10201710928PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
SG10201710928PA 2013-03-14 2014-03-14 Ocular formulations for drug-delivery to the posterior segment of the eye SG10201710928PA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361784681P 2013-03-14 2013-03-14

Publications (1)

Publication Number Publication Date
SG10201710928PA true SG10201710928PA (en) 2018-02-27

Family

ID=50625096

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201507316UA SG11201507316UA (en) 2013-03-14 2014-03-14 Ocular formulations for drug-delivery to the posterior segment of the eye
SG10201710928PA SG10201710928PA (en) 2013-03-14 2014-03-14 Ocular formulations for drug-delivery to the posterior segment of the eye

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201507316UA SG11201507316UA (en) 2013-03-14 2014-03-14 Ocular formulations for drug-delivery to the posterior segment of the eye

Country Status (23)

Country Link
US (7) US10092549B2 (en)
EP (2) EP2968650B1 (en)
JP (3) JP6542193B2 (en)
KR (2) KR20210132205A (en)
CN (2) CN111789814B (en)
AU (3) AU2014239252B2 (en)
BR (1) BR112015021334B1 (en)
CA (1) CA2900840C (en)
DK (1) DK2968650T3 (en)
ES (1) ES2710152T3 (en)
HK (1) HK1216236A1 (en)
HU (1) HUE042528T2 (en)
IL (2) IL240510B (en)
MX (1) MX360888B (en)
PH (2) PH12015501938A1 (en)
PL (1) PL2968650T3 (en)
PT (1) PT2968650T (en)
RU (2) RU2768489C2 (en)
SA (1) SA516380321B1 (en)
SG (2) SG11201507316UA (en)
TR (1) TR201901462T4 (en)
WO (1) WO2014152661A1 (en)
ZA (2) ZA201505447B (en)

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KR102450020B1 (en) * 2014-09-17 2022-09-30 팬옵티카, 인크. Ocular formulations for drug-delivery and protection of the anterior segment of the eye
JP6602964B2 (en) 2015-09-30 2019-11-06 ノバリック ゲーエムベーハー Semifluorinated compounds and compositions thereof
AU2017229870B2 (en) 2016-03-11 2023-01-12 Georgia-Pacific Gypsum Llc Gypsum panels, systems, and methods
CA3058097C (en) * 2017-04-21 2024-01-02 Novaliq Gmbh Iodine compositions
US11278503B2 (en) 2017-05-12 2022-03-22 Novaliq Gmbh Pharmaceutical compositions comprising semifluorinated alkanes for the treatment of contact lense-related conditions
RU2652342C1 (en) * 2017-07-13 2018-04-25 Наталья Александровна Гаврилова Composition for treatment of retinal neovascularization in experiment and method of treatment with its implementation
JP2020535156A (en) 2017-09-27 2020-12-03 ノバリック ゲーエムベーハー Ophthalmic composition containing latanoprost for use in the treatment of eye diseases
WO2019068763A1 (en) 2017-10-04 2019-04-11 Novaliq Gmbh Ophthalmic compositions comprising f6h8
AT522609B1 (en) 2019-05-28 2022-06-15 Miba Frictec Gmbh friction device
AU2022268925A1 (en) 2021-05-03 2023-11-16 Avilar Therapeutics, Inc. Potent asgpr-binding compounds for the degradation of immunoglobulins and other proteins

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UA60365C2 (en) 1998-06-04 2003-10-15 Пфайзер Продактс Інк. Isothiazole derivatives, a method for preparing thereof, a pharmaceutical composition and a method for treatment of hyperproliferative disease of mammal
US6239113B1 (en) * 1999-03-31 2001-05-29 Insite Vision, Incorporated Topical treatment or prevention of ocular infections
US6254860B1 (en) * 1999-04-13 2001-07-03 Allergan Sales, Inc. Ocular treatment using cyclosporin-A derivatives
JP4682495B2 (en) * 1999-09-06 2011-05-11 小野薬品工業株式会社 Prevention and treatment of eye diseases
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Also Published As

Publication number Publication date
JP2022009275A (en) 2022-01-14
US20190247368A1 (en) 2019-08-15
WO2014152661A1 (en) 2014-09-25
SA516380321B1 (en) 2019-01-16
PH12019501902A1 (en) 2021-03-01
JP2019167377A (en) 2019-10-03
AU2017210543A1 (en) 2017-08-17
JP2016517427A (en) 2016-06-16
ZA201505447B (en) 2022-06-29
US10307404B1 (en) 2019-06-04
RU2015143898A (en) 2017-04-19
HK1216236A1 (en) 2016-10-28
US9446026B2 (en) 2016-09-20
US20160022646A1 (en) 2016-01-28
AU2019202857B2 (en) 2021-02-18
US20210196690A1 (en) 2021-07-01
RU2018128980A3 (en) 2022-01-11
BR112015021334B1 (en) 2020-04-07
JP6965308B2 (en) 2021-11-10
EP2968650B1 (en) 2019-01-16
CA2900840A1 (en) 2014-09-25
IL276016B (en) 2022-04-01
TR201901462T4 (en) 2019-02-21
CN111789814A (en) 2020-10-20
AU2017210543B2 (en) 2019-01-31
US10092549B2 (en) 2018-10-09
JP6542193B2 (en) 2019-07-10
EP3520773A1 (en) 2019-08-07
PL2968650T3 (en) 2019-05-31
CN105142686A (en) 2015-12-09
US20140303219A1 (en) 2014-10-09
IL240510A0 (en) 2015-10-29
AU2014239252A1 (en) 2015-08-13
PT2968650T (en) 2019-02-12
SG11201507316UA (en) 2015-10-29
CN111789814B (en) 2022-07-19
US20160354349A1 (en) 2016-12-08
PH12015501938B1 (en) 2016-01-11
CN105142686B (en) 2020-04-10
RU2768489C2 (en) 2022-03-24
ES2710152T3 (en) 2019-04-23
HUE042528T2 (en) 2019-07-29
EP2968650A1 (en) 2016-01-20
KR102433489B1 (en) 2022-08-17
US20190240201A1 (en) 2019-08-08
US20190183864A1 (en) 2019-06-20
RU2665953C2 (en) 2018-09-05
CA2900840C (en) 2023-03-28
AU2019202857A1 (en) 2019-05-16
IL240510B (en) 2020-08-31
ZA201907176B (en) 2022-12-21
RU2018128980A (en) 2018-11-05
KR20150127256A (en) 2015-11-16
MX2015012653A (en) 2016-08-18
PH12015501938A1 (en) 2016-01-11
MX360888B (en) 2018-11-20
DK2968650T3 (en) 2019-03-11
IL276016A (en) 2020-08-31
BR112015021334A2 (en) 2017-07-18
KR20210132205A (en) 2021-11-03
AU2014239252B2 (en) 2017-07-06

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