SG10201707565WA - Oligosaccharide compositions, glycoproteins and methods to produce the same in prokaryotes - Google Patents

Oligosaccharide compositions, glycoproteins and methods to produce the same in prokaryotes

Info

Publication number
SG10201707565WA
SG10201707565WA SG10201707565WA SG10201707565WA SG10201707565WA SG 10201707565W A SG10201707565W A SG 10201707565WA SG 10201707565W A SG10201707565W A SG 10201707565WA SG 10201707565W A SG10201707565W A SG 10201707565WA SG 10201707565W A SG10201707565W A SG 10201707565WA
Authority
SG
Singapore
Prior art keywords
prokaryotes
glycoproteins
produce
methods
same
Prior art date
Application number
SG10201707565WA
Inventor
Adam C Fisher
Judith H Merritt
Brian S Hamilton
Juan D Valderrama-Rincon
Matthew P Delisa
Original Assignee
Glycobia Inc
Adam C Fisher
Judith H Merritt
Brian S Hamilton
Juan D Valderrama-Rincon
Matthew P Delisa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycobia Inc, Adam C Fisher, Judith H Merritt, Brian S Hamilton, Juan D Valderrama-Rincon, Matthew P Delisa filed Critical Glycobia Inc
Publication of SG10201707565WA publication Critical patent/SG10201707565WA/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0258—Escherichia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/01—Hexosyltransferases (2.4.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG10201707565WA 2013-03-14 2014-03-14 Oligosaccharide compositions, glycoproteins and methods to produce the same in prokaryotes SG10201707565WA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361785586P 2013-03-14 2013-03-14

Publications (1)

Publication Number Publication Date
SG10201707565WA true SG10201707565WA (en) 2017-10-30

Family

ID=51528818

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201508347YA SG11201508347YA (en) 2013-03-14 2014-03-14 Oligosaccharide compositions, glycoproteins and methods to produce the same in prokaryotes
SG10201707565WA SG10201707565WA (en) 2013-03-14 2014-03-14 Oligosaccharide compositions, glycoproteins and methods to produce the same in prokaryotes

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201508347YA SG11201508347YA (en) 2013-03-14 2014-03-14 Oligosaccharide compositions, glycoproteins and methods to produce the same in prokaryotes

Country Status (8)

Country Link
US (2) US20160177355A1 (en)
EP (1) EP2971030B8 (en)
JP (1) JP2016518114A (en)
KR (1) KR20160021075A (en)
CN (1) CN105378096A (en)
CA (1) CA2906671A1 (en)
SG (2) SG11201508347YA (en)
WO (1) WO2014152137A2 (en)

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CN104388372B (en) * 2014-12-04 2017-07-21 江南大学 A kind of recombined bacillus subtilis for producing chondroitin and its application
JP6762027B2 (en) * 2016-08-25 2020-09-30 株式会社雅嘉貿易 Manufacturing method of cyanooligosaccharide and its use
BR112019015425A2 (en) 2017-01-27 2020-05-26 University Of Florida Research Foundation, Incorporated A FOOD SAFETY VACCINE TO CONTROL SALMONELLA ENTERICA AND REDUCE CAMPYLOBACTER IN POULTRY
WO2020044371A1 (en) * 2018-08-29 2020-03-05 Council Of Scientific And Industrial Research Recombinant microbial system for directed evolution of glycocins and a method of preparation thereof
CN110294810B (en) * 2019-06-26 2021-05-04 中国疾病预防控制中心传染病预防控制所 Recombinant protein containing human IgG1Fc and mannan-binding lectin C-terminal
CN111534495B (en) * 2020-05-14 2022-06-17 江南大学 Method for improving soluble expression of recombinant N-acetylglucosamine transferase II
WO2022162704A1 (en) * 2021-02-01 2022-08-04 Dr. Reddy's Laboratories Limited Compositions comprising fusion protein and analytical attributes thereof
WO2023122641A1 (en) * 2021-12-22 2023-06-29 Zymergen Inc. Compositions and methods for producing acetic acid and polysaccharides
EP4265730A1 (en) * 2022-04-19 2023-10-25 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Cell-free enzymatic method for preparation of n-glycans
WO2023202991A2 (en) 2022-04-19 2023-10-26 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Cell-free enzymatic method for preparation of n-glycans

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US5834251A (en) * 1994-12-30 1998-11-10 Alko Group Ltd. Methods of modifying carbohydrate moieties
DE19754622A1 (en) * 1997-12-09 1999-06-10 Antje Von Dr Schaewen Plant GntI sequences and the use thereof for obtaining plants with reduced or missing N-acetylglucosaminyltransferase I (GnTI) activity
EP1131415A4 (en) * 1998-11-18 2002-09-11 Neose Technologies Inc Low cost manufacture of oligosaccharides
US8697394B2 (en) * 2000-06-28 2014-04-15 Glycofi, Inc. Production of modified glycoproteins having multiple antennary structures
US7449308B2 (en) * 2000-06-28 2008-11-11 Glycofi, Inc. Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
US20030003097A1 (en) * 2001-04-02 2003-01-02 Idec Pharmaceutical Corporation Recombinant antibodies coexpressed with GnTIII
US7795210B2 (en) * 2001-10-10 2010-09-14 Novo Nordisk A/S Protein remodeling methods and proteins/peptides produced by the methods
US7691599B2 (en) * 2002-05-02 2010-04-06 Zirus, Inc. Mammalian genes involved in viral infection and tumor suppression
CA2591992A1 (en) * 2004-12-22 2006-06-29 The Salk Institute For Biological Studies Compositions and methods for producing recombinant proteins
CN101137757A (en) * 2005-03-07 2008-03-05 植物研究国际公司 Glycoengineering in mushrooms
WO2006102652A2 (en) * 2005-03-24 2006-09-28 Neose Technologies, Inc. Expression of soluble, active eukaryotic glycosyltransferases in prokaryotic organisms
WO2006112025A1 (en) * 2005-04-15 2006-10-26 Japan Tobacco Inc. NOVEL β-GALACTOSIDE-α-2,3-SIALYLTRANSFERASE, GENE ENCODING THE SAME AND METHOD FOR PRODUCING THE SAME
US8198045B2 (en) * 2006-04-19 2012-06-12 Biogenerix Ag Expression of O-glycosylated therapeutic proteins in prokaryotic microorganisms
WO2009089154A2 (en) * 2008-01-03 2009-07-16 Cornell Research Foundation, Inc. Glycosylated protein expression in prokaryotes
US9927440B2 (en) * 2009-11-25 2018-03-27 Duke University Protein engineering
US9051593B2 (en) * 2009-12-21 2015-06-09 Trustees Of Dartmouth College Recombinant prokaryotes and use thereof for production of O-glycosylated proteins
WO2012050175A1 (en) * 2010-10-15 2012-04-19 日本ケミカルリサーチ株式会社 Method for producing glycoprotein having mannose residue as non-reducing end of sugar chain
US9399764B2 (en) * 2010-11-24 2016-07-26 Novartis International Pharmaceutical, Ltd. Fusion enzymes
JP5975577B2 (en) * 2011-03-04 2016-08-23 株式会社糖鎖工学研究所 Method for producing sialic acid-containing sugar chain
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Also Published As

Publication number Publication date
SG11201508347YA (en) 2015-11-27
EP2971030B8 (en) 2018-12-05
CN105378096A (en) 2016-03-02
KR20160021075A (en) 2016-02-24
EP2971030B1 (en) 2018-10-17
EP2971030A4 (en) 2017-03-15
US20160177355A1 (en) 2016-06-23
WO2014152137A8 (en) 2015-12-30
JP2016518114A (en) 2016-06-23
WO2014152137A2 (en) 2014-09-25
US20140273163A1 (en) 2014-09-18
EP2971030A2 (en) 2016-01-20
CA2906671A1 (en) 2014-09-25
WO2014152137A3 (en) 2014-12-11

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