SG10201705852PA - Pyridine derivative - Google Patents

Pyridine derivative

Info

Publication number: SG10201705852PA
Authority: SG; Singapore
Prior art keywords: pyridine derivative; pyridine; derivative
Prior art date: 2012-11-14

Application number

SG10201705852PA

Inventor

Akinobu Maruyama

Hirofumi Kamada

Mika Fujinuma

Susumu Takeuchi

Hiroshi Saitoh

Yoshimasa Takahashi

Original Assignee

Teijin Pharma Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-11-14

Filing date

2013-11-13

Publication date

2017-08-30

2013-11-13 Application filed by Teijin Pharma Ltd filed Critical Teijin Pharma Ltd

2017-08-30 Publication of SG10201705852PA publication Critical patent/SG10201705852PA/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Urology & Nephrology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Obesity (AREA)
Hematology (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heat Sensitive Colour Forming Recording (AREA)
Beans For Foods Or Fodder (AREA)

SG10201705852PA 2012-11-14 2013-11-13 Pyridine derivative SG10201705852PA (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2012250661		2012-11-14

Publications (1)

Publication Number	Publication Date
SG10201705852PA true SG10201705852PA (en)	2017-08-30

Family

ID=50731196

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SG11201503770VA SG11201503770VA (en)	2012-11-14	2013-11-13	Pyridine derivative
SG10201705852PA SG10201705852PA (en)	2012-11-14	2013-11-13	Pyridine derivative

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
SG11201503770VA SG11201503770VA (en)	2012-11-14	2013-11-13	Pyridine derivative

Country Status (36)

Country	Link
US (2)	US9637469B2 (en)
EP (2)	EP3339302A1 (en)
JP (2)	JP5774238B2 (en)
KR (1)	KR20150082194A (en)
CN (2)	CN104797570B (en)
AR (1)	AR093468A1 (en)
AU (2)	AU2013345894B2 (en)
BR (1)	BR112015010977A2 (en)
CA (1)	CA2891408A1 (en)
CL (1)	CL2015001279A1 (en)
CY (1)	CY1120127T1 (en)
DK (1)	DK2944633T3 (en)
ES (1)	ES2662444T3 (en)
HK (1)	HK1211940A1 (en)
HR (1)	HRP20180451T1 (en)
HU (1)	HUE037736T2 (en)
IL (2)	IL238539A (en)
LT (1)	LT2944633T (en)
MA (1)	MA38078B1 (en)
ME (1)	ME03016B (en)
MX (1)	MX2015003672A (en)
NO (1)	NO2944633T3 (en)
NZ (1)	NZ708031A (en)
PE (1)	PE20150974A1 (en)
PH (1)	PH12015501037A1 (en)
PL (1)	PL2944633T3 (en)
PT (1)	PT2944633T (en)
RS (1)	RS57090B1 (en)
RU (1)	RU2640588C2 (en)
SA (1)	SA515360431B1 (en)
SG (2)	SG11201503770VA (en)
SI (1)	SI2944633T1 (en)
TW (1)	TWI666205B (en)
UA (1)	UA117359C2 (en)
WO (1)	WO2014077285A1 (en)
ZA (1)	ZA201503322B (en)

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AU2015260294A1 (en) *	2014-05-13	2017-01-05	Teijin Pharma Limited	Novel crystalline polymorph of pyridine derivative, and method for producing same
SI3144306T1 (en) *	2014-05-13	2018-02-28	Teijin Pharma Limited	Pyrazine derivative
JP2019510020A (en)	2016-03-15	2019-04-11	バイエル・クロップサイエンス・アクチェンゲゼルシャフト	Substituted sulfonylamides for controlling pests
CN107286156A (en) *	2016-04-05	2017-10-24	江苏新元素医药科技有限公司	New URAT1 inhibitor and its in application pharmaceutically
CN106008488B (en) *	2016-05-20	2018-10-30	广东东阳光药业有限公司	Cyanoindole analog derivative and its preparation method and application
AU2017270858B2 (en)	2016-05-23	2019-09-19	Dongbao Purple Star (Hangzhou) Biopharmaceutical Co., Ltd.	Thiophene, manufacturing method thereof, and pharmaceutical application of same
TW201822637A (en)	2016-11-07	2018-07-01	德商拜耳廠股份有限公司	Substituted sulfonamides for controlling animal pests
MX2019008229A (en)	2017-01-10	2019-10-24	Bayer Ag	Heterocyclene derivatives as pest control agents.
CN110312718B (en)	2017-01-10	2023-02-28	拜耳公司	Heterocyclene derivatives as pest control agents
CN108658879A (en) *	2017-03-29	2018-10-16	天津药物研究院有限公司	A kind of URAT1 inhibitor and its preparation method and application
CN109251184B (en) *	2017-07-13	2021-06-15	浙江海正药业股份有限公司	Medical application of 2-trifluoromethyl benzene sulfonamide derivative
JP7268049B2 (en)	2018-03-08	2023-05-02	インサイト・コーポレイション	Aminopyrazinediol compounds as PI3K-γ inhibitors
US11046658B2 (en)	2018-07-02	2021-06-29	Incyte Corporation	Aminopyrazine derivatives as PI3K-γ inhibitors
TWI820231B (en)	2018-10-11	2023-11-01	德商拜耳廠股份有限公司	Process for preparing substituted imidazole derivatives
CN111943957B (en) *	2019-05-17	2023-01-06	中国医学科学院药物研究所	Quinoline formamide compound and preparation method and application thereof
WO2021089673A1 (en)	2019-11-07	2021-05-14	Bayer Aktiengesellschaft	Substituted sulfonyl amides for controlling animal pests
BR112022026904A2 (en)	2020-07-02	2023-01-24	Bayer Ag	HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS
CN114315729B (en) *	2021-12-09	2024-01-26	大连理工大学	1-benzyl-2, 4-diaryl imidazole compound, synthetic method and application thereof in resisting tumor

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2013
- 2013-11-13 ES ES13854714T patent/ES2662444T3/en active Active
- 2013-11-13 PE PE2015000616A patent/PE20150974A1/en not_active Application Discontinuation
- 2013-11-13 DK DK13854714.6T patent/DK2944633T3/en active
- 2013-11-13 WO PCT/JP2013/080706 patent/WO2014077285A1/en active Application Filing
- 2013-11-13 US US14/441,074 patent/US9637469B2/en active Active
- 2013-11-13 ME MEP-2018-91A patent/ME03016B/en unknown
- 2013-11-13 AR ARP130104172A patent/AR093468A1/en unknown
- 2013-11-13 RS RS20180390A patent/RS57090B1/en unknown
- 2013-11-13 LT LTEP13854714.6T patent/LT2944633T/en unknown
- 2013-11-13 HU HUE13854714A patent/HUE037736T2/en unknown
- 2013-11-13 MX MX2015003672A patent/MX2015003672A/en unknown
- 2013-11-13 PT PT138547146T patent/PT2944633T/en unknown
- 2013-11-13 SI SI201330943T patent/SI2944633T1/en unknown
- 2013-11-13 EP EP18152142.8A patent/EP3339302A1/en not_active Withdrawn
- 2013-11-13 EP EP13854714.6A patent/EP2944633B1/en active Active
- 2013-11-13 KR KR1020157008457A patent/KR20150082194A/en not_active Application Discontinuation
- 2013-11-13 MA MA38078A patent/MA38078B1/en unknown
- 2013-11-13 TW TW102141292A patent/TWI666205B/en not_active IP Right Cessation
- 2013-11-13 NZ NZ708031A patent/NZ708031A/en not_active IP Right Cessation
- 2013-11-13 PL PL13854714T patent/PL2944633T3/en unknown
- 2013-11-13 SG SG11201503770VA patent/SG11201503770VA/en unknown
- 2013-11-13 UA UAA201505767A patent/UA117359C2/en unknown
- 2013-11-13 NO NO13854714A patent/NO2944633T3/no unknown
- 2013-11-13 JP JP2014547007A patent/JP5774238B2/en not_active Expired - Fee Related
- 2013-11-13 AU AU2013345894A patent/AU2013345894B2/en not_active Ceased
- 2013-11-13 SG SG10201705852PA patent/SG10201705852PA/en unknown
- 2013-11-13 CA CA2891408A patent/CA2891408A1/en not_active Abandoned
- 2013-11-13 CN CN201380059519.0A patent/CN104797570B/en not_active Expired - Fee Related
- 2013-11-13 RU RU2015122698A patent/RU2640588C2/en active
- 2013-11-13 BR BR112015010977A patent/BR112015010977A2/en not_active Application Discontinuation
- 2013-11-13 CN CN201710933918.5A patent/CN107721931A/en active Pending
2015
- 2015-01-16 JP JP2015007229A patent/JP6293068B2/en not_active Expired - Fee Related
- 2015-04-30 IL IL238539A patent/IL238539A/en not_active IP Right Cessation
- 2015-05-08 PH PH12015501037A patent/PH12015501037A1/en unknown
- 2015-05-12 CL CL2015001279A patent/CL2015001279A1/en unknown
- 2015-05-13 ZA ZA2015/03322A patent/ZA201503322B/en unknown
- 2015-05-13 SA SA515360431A patent/SA515360431B1/en unknown
- 2015-12-17 IL IL243193A patent/IL243193A0/en unknown
- 2015-12-31 HK HK15112873.0A patent/HK1211940A1/en not_active IP Right Cessation
2017
- 2017-03-22 US US15/466,088 patent/US20170190694A1/en not_active Abandoned
- 2017-07-07 AU AU2017204665A patent/AU2017204665A1/en not_active Abandoned
2018
- 2018-03-16 HR HRP20180451TT patent/HRP20180451T1/en unknown
- 2018-04-10 CY CY20181100389T patent/CY1120127T1/en unknown

Also Published As

Publication number	Publication date
MA38078B1 (en)	2017-04-28
WO2014077285A1 (en)	2014-05-22
SI2944633T1 (en)	2018-06-29
MX2015003672A (en)	2015-06-15
CN104797570A (en)	2015-07-22
CN107721931A (en)	2018-02-23
SG11201503770VA (en)	2015-06-29
NZ708031A (en)	2018-04-27
MA38078A1 (en)	2016-09-30
BR112015010977A2 (en)	2017-07-11
US9637469B2 (en)	2017-05-02
IL243193A0 (en)	2016-02-29
SA515360431B1 (en)	2017-11-15
JP6293068B2 (en)	2018-03-14
AU2013345894A9 (en)	2015-11-12
EP2944633A1 (en)	2015-11-18
JP5774238B2 (en)	2015-09-09
RU2640588C2 (en)	2018-01-10
DK2944633T3 (en)	2018-03-12
HRP20180451T1 (en)	2018-06-01
PT2944633T (en)	2018-05-09
PH12015501037A1 (en)	2015-07-27
EP2944633B1 (en)	2018-01-31
PL2944633T3 (en)	2018-08-31
RU2015122698A (en)	2017-01-10
TWI666205B (en)	2019-07-21
ZA201503322B (en)	2016-01-27
IL238539A0 (en)	2015-06-30
TW201422603A (en)	2014-06-16
RS57090B1 (en)	2018-06-29
JPWO2014077285A1 (en)	2017-01-05
HK1211940A1 (en)	2016-06-03
CL2015001279A1 (en)	2015-06-26
JP2015091865A (en)	2015-05-14
HUE037736T2 (en)	2018-09-28
UA117359C2 (en)	2018-07-25
CA2891408A1 (en)	2014-05-22
EP3339302A1 (en)	2018-06-27
CY1120127T1 (en)	2018-12-12
NO2944633T3 (en)	2018-06-30
AU2013345894A1 (en)	2015-05-21
KR20150082194A (en)	2015-07-15
IL238539A (en)	2017-11-30
ME03016B (en)	2018-10-20
AU2017204665A1 (en)	2017-07-27
AR093468A1 (en)	2015-06-10
EP2944633A4 (en)	2016-01-06
PE20150974A1 (en)	2015-07-04
AU2013345894B2 (en)	2017-05-25
US20150284358A1 (en)	2015-10-08
CN104797570B (en)	2017-11-07
LT2944633T (en)	2018-03-12
US20170190694A1 (en)	2017-07-06
ES2662444T3 (en)	2018-04-06

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