SG10201700593YA - Nme variant species expression and suppression - Google Patents

Nme variant species expression and suppression

Info

Publication number
SG10201700593YA
SG10201700593YA SG10201700593YA SG10201700593YA SG10201700593YA SG 10201700593Y A SG10201700593Y A SG 10201700593YA SG 10201700593Y A SG10201700593Y A SG 10201700593YA SG 10201700593Y A SG10201700593Y A SG 10201700593YA SG 10201700593Y A SG10201700593Y A SG 10201700593YA
Authority
SG
Singapore
Prior art keywords
suppression
variant species
species expression
nme
nme variant
Prior art date
Application number
SG10201700593YA
Inventor
Cynthia Bamdad
Original Assignee
Minerva Biotechnologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2012/060684 external-priority patent/WO2013059373A2/en
Application filed by Minerva Biotechnologies Corp filed Critical Minerva Biotechnologies Corp
Publication of SG10201700593YA publication Critical patent/SG10201700593YA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/727—Kinases (EC 2.7.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998—Proteins not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Reproductive Health (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG10201700593YA 2012-07-24 2013-07-24 Nme variant species expression and suppression SG10201700593YA (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261675292P 2012-07-24 2012-07-24
US201261677442P 2012-07-30 2012-07-30
US201261679021P 2012-08-02 2012-08-02
US201261683155P 2012-08-14 2012-08-14
US201261684654P 2012-08-17 2012-08-17
US201261693712P 2012-08-27 2012-08-27
PCT/US2012/060684 WO2013059373A2 (en) 2011-10-17 2012-10-17 Media for stem cell proliferation and induction

Publications (1)

Publication Number Publication Date
SG10201700593YA true SG10201700593YA (en) 2017-03-30

Family

ID=49997968

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201700593YA SG10201700593YA (en) 2012-07-24 2013-07-24 Nme variant species expression and suppression
SG11201606118SA SG11201606118SA (en) 2012-07-24 2013-07-24 Nme variant species expression and suppression

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201606118SA SG11201606118SA (en) 2012-07-24 2013-07-24 Nme variant species expression and suppression

Country Status (9)

Country Link
US (2) US20150203823A1 (en)
EP (2) EP2877586A4 (en)
JP (3) JP6546087B2 (en)
CN (2) CN111849874A (en)
AU (2) AU2013295811A1 (en)
CA (1) CA2880010A1 (en)
IL (1) IL236901B (en)
SG (2) SG10201700593YA (en)
WO (1) WO2014018679A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013059373A2 (en) 2011-10-17 2013-04-25 Minerva Biotechnologies Corporation Media for stem cell proliferation and induction
JP6640086B2 (en) * 2013-08-12 2020-02-05 ミネルバ バイオテクノロジーズ コーポレーション How to enhance tumor growth
US20170204196A1 (en) * 2014-04-07 2017-07-20 Minerva Biotechnologies Corporation Anti-nme antibody
CN107660213B (en) 2015-02-10 2023-01-13 米纳瓦生物技术公司 Humanized anti-MUCl antibodies
CN109081863A (en) * 2018-08-01 2018-12-25 西北民族大学 The isolation and identification method of anti-cancer active matter D actinomycin D FGR
JP2022519120A (en) 2019-02-04 2022-03-18 ミネルヴァ バイオテクノロジーズ コーポレーション Anti-NME antibody and treatment of cancer or cancer metastasis
JP2023530039A (en) 2020-06-08 2023-07-12 ミネルバ バイオテクノロジーズ コーポレーション Anti-NME Antibodies and Methods of Treating Cancer or Cancer Metastasis

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2329822A1 (en) * 2001-09-05 2011-06-08 Minerva Biotechnologies Corporation Compositions and methods of treatment of cancer
EP1375661A1 (en) * 2002-06-17 2004-01-02 Academisch Ziekenhuis Bij De Universiteit Van Amsterdam The role of the N-myc - nm23H1/nm23H2 - cdc42 pathway in proliferation, differentiation and treatment of cancer
CN101273060A (en) * 2005-06-24 2008-09-24 美国政府（由卫生和人类服务部、国立卫生研究院的部长所代表） Amelioration of inflammatory arthritis by targeting the pre-ligand assembly domain (PLAD) of tumor necrosis factor receptors
JP2008099662A (en) * 2006-09-22 2008-05-01 Institute Of Physical & Chemical Research Method for culturing stem cell
WO2008067065A2 (en) * 2006-10-19 2008-06-05 Shiv Srivastava Methods, kits, and systems for diagnosing and prognosing prostate cancer using secreted biomarkers
CN101652469B (en) * 2006-12-06 2014-04-16 米纳瓦生物技术公司 Method for identifying and manipulating cells
WO2009012173A2 (en) 2007-07-13 2009-01-22 Dharmacon, Inc. Enhanced biotherapeutic production using inhibitory rna
KR20200133324A (en) * 2008-10-09 2020-11-27 미네르바 바이오테크놀로지 코포레이션 Method for inducing pluripotency in cells
KR20170075023A (en) * 2009-06-11 2017-06-30 미네르바 바이오테크놀로지 코포레이션 Methods for culturing stem and progenitor cells
CN109112097A (en) * 2010-06-16 2019-01-01 米纳瓦生物技术公司 Reprogram cancer cell
EP2872636A4 (en) * 2012-07-13 2016-08-17 Minerva Biotechnologies Corp Method for inducing cells to less mature state

Also Published As

Publication number Publication date
SG11201606118SA (en) 2016-08-30
JP2019141100A (en) 2019-08-29
CN111849874A (en) 2020-10-30
JP2021192614A (en) 2021-12-23
AU2013295811A1 (en) 2015-03-12
JP6546087B2 (en) 2019-07-17
AU2019203098B2 (en) 2021-04-08
WO2014018679A3 (en) 2015-05-07
EP2877586A4 (en) 2016-02-17
US20230049461A1 (en) 2023-02-16
CA2880010A1 (en) 2014-01-30
IL236901A0 (en) 2015-03-31
IL236901B (en) 2021-03-25
JP7386210B2 (en) 2023-11-24
CN104995518A (en) 2015-10-21
US20150203823A1 (en) 2015-07-23
AU2019203098A1 (en) 2019-05-23
EP2877586A2 (en) 2015-06-03
EP4206318A1 (en) 2023-07-05
WO2014018679A2 (en) 2014-01-30
JP2015529454A (en) 2015-10-08

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