SG10201602846TA - 4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives, their manufacture and use as antiviral agents - Google Patents

4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives, their manufacture and use as antiviral agents

Info

Publication number: SG10201602846TA
Authority: SG; Singapore
Prior art keywords: phenylpyrazolo; phenylamino; amino; manufacture; antiviral agents
Prior art date: 2011-10-14

Application number

SG10201602846TA

Inventor

Peter Wutzler

Michaela Schmidtke

Vadim Makarov

Original Assignee

Dritte Patentportfolio Beteiligungs Gmbh & Co Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-10-14

Filing date

2012-10-15

Publication date

2016-05-30

2011-10-14 Priority claimed from DE201110116373 external-priority patent/DE102011116373A1/en

2012-10-15 Application filed by Dritte Patentportfolio Beteiligungs Gmbh & Co Kg filed Critical Dritte Patentportfolio Beteiligungs Gmbh & Co Kg

2016-05-30 Publication of SG10201602846TA publication Critical patent/SG10201602846TA/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Pulmonology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

SG10201602846TA 2011-10-14 2012-10-15 4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives, their manufacture and use as antiviral agents SG10201602846TA (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE201110116373 DE102011116373A1 (en)	2011-10-14	2011-10-14	Preparing substituted amino-phenylamino-phenyl-pyrazolo(3,4-d)pyrimidine derivatives useful e.g. for treating picornavirus infection, comprises reacting substituted amino-phenylamino-pyrazole-carbonitrile compounds and benzamidine compounds
DE102011116384		2011-10-20

Publications (1)

Publication Number	Publication Date
SG10201602846TA true SG10201602846TA (en)	2016-05-30

Family

ID=47071252

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SG10201602846TA SG10201602846TA (en)	2011-10-14	2012-10-15	4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives, their manufacture and use as antiviral agents
SG11201401351PA SG11201401351PA (en)	2011-10-14	2012-10-15	4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d] pyrimidine derivatives, their manufacture and their use as antiviral active substances

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SG11201401351PA SG11201401351PA (en)	2011-10-14	2012-10-15	4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d] pyrimidine derivatives, their manufacture and their use as antiviral active substances

Country Status (22)

Country	Link
US (1)	US9790225B2 (en)
EP (1)	EP2766367B1 (en)
JP (1)	JP6071012B2 (en)
KR (1)	KR20140095467A (en)
CN (1)	CN103946224A (en)
AU (1)	AU2012322750B2 (en)
BR (1)	BR112014008815B1 (en)
CA (1)	CA2850439C (en)
DK (1)	DK2766367T3 (en)
ES (1)	ES2924828T3 (en)
HR (1)	HRP20220928T1 (en)
HU (1)	HUE059217T2 (en)
IL (1)	IL231934A (en)
LT (1)	LT2766367T (en)
MX (1)	MX2014003987A (en)
PL (1)	PL2766367T3 (en)
PT (1)	PT2766367T (en)
RU (1)	RU2014118953A (en)
SG (2)	SG10201602846TA (en)
SI (1)	SI2766367T1 (en)
WO (1)	WO2013053942A1 (en)
ZA (1)	ZA201402226B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP3064207B1 (en) *	2015-03-04	2017-12-20	Scandion Oncology A/S	4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives for use as BCRP inhibitors in therapeutic treatments
KR102205570B1 (en)	2018-09-12	2021-01-20	김홍기	Root plant hydroponic cultivation sheet

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2965643A (en)		1960-12-20		Derivatives of pyrazolo
US3551428A (en)	1956-02-10	1970-12-29	Ciba Geigy Corp	New 1- (or 2-) substituted 4-mercapto-pyrazolo(3,4-d)pyrimidines
DE3712735A1 (en)	1987-04-15	1988-11-10	Boehringer Mannheim Gmbh	NEW PYRAZOLO (3,4-D) PYRIMIDINE, METHOD FOR THE PRODUCTION AND USE THEREOF AS A MEDICINAL PRODUCT
CA2100863A1 (en)	1991-01-23	1992-07-24	David A. Bullough	Adenosine kinase inhibitors
TW444018B (en)	1992-12-17	2001-07-01	Pfizer	Pyrazolopyrimidines
US5646152A (en)	1994-06-15	1997-07-08	Pfizer Inc.	Methods of administering CRF antagonists
CZ27399A3 (en)	1999-01-26	2000-08-16	Ústav Experimentální Botaniky Av Čr	Substituted nitrogen heterocyclic derivatives process of their preparation, the derivatives employed as medicaments, pharmaceutical composition and a compound pharmaceutical preparation in which these derivatives are comprised as well as use of these derivatives for preparing medicaments
DE102006029074A1 (en) *	2006-06-22	2007-12-27	Friedrich-Schiller-Universität Jena	4-Amino-3-arylamino-6-arylpyrazolo [3,4-d] pyrimidine derivatives, process for their preparation and their use as antiviral agents

2012
- 2012-10-15 PL PL12775659.1T patent/PL2766367T3/en unknown
- 2012-10-15 PT PT127756591T patent/PT2766367T/en unknown
- 2012-10-15 KR KR1020147009385A patent/KR20140095467A/en not_active Application Discontinuation
- 2012-10-15 ES ES12775659T patent/ES2924828T3/en active Active
- 2012-10-15 RU RU2014118953/04A patent/RU2014118953A/en not_active Application Discontinuation
- 2012-10-15 HU HUE12775659A patent/HUE059217T2/en unknown
- 2012-10-15 US US14/350,885 patent/US9790225B2/en active Active
- 2012-10-15 CN CN201280050298.6A patent/CN103946224A/en active Pending
- 2012-10-15 SI SI201232005T patent/SI2766367T1/en unknown
- 2012-10-15 CA CA2850439A patent/CA2850439C/en active Active
- 2012-10-15 AU AU2012322750A patent/AU2012322750B2/en active Active
- 2012-10-15 EP EP12775659.1A patent/EP2766367B1/en active Active
- 2012-10-15 LT LTEPPCT/EP2012/070403T patent/LT2766367T/en unknown
- 2012-10-15 JP JP2014535117A patent/JP6071012B2/en active Active
- 2012-10-15 SG SG10201602846TA patent/SG10201602846TA/en unknown
- 2012-10-15 DK DK12775659.1T patent/DK2766367T3/en active
- 2012-10-15 HR HRP20220928TT patent/HRP20220928T1/en unknown
- 2012-10-15 BR BR112014008815-2A patent/BR112014008815B1/en active IP Right Grant
- 2012-10-15 SG SG11201401351PA patent/SG11201401351PA/en unknown
- 2012-10-15 WO PCT/EP2012/070403 patent/WO2013053942A1/en active Application Filing
- 2012-10-15 MX MX2014003987A patent/MX2014003987A/en unknown
2014
- 2014-03-26 ZA ZA2014/02226A patent/ZA201402226B/en unknown
- 2014-04-03 IL IL231934A patent/IL231934A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
SI2766367T1 (en)	2022-10-28
WO2013053942A1 (en)	2013-04-18
EP2766367B1 (en)	2022-05-18
IL231934A0 (en)	2014-05-28
AU2012322750B2 (en)	2016-11-10
US20140296259A1 (en)	2014-10-02
AU2012322750A1 (en)	2014-04-24
ES2924828T3 (en)	2022-10-11
HRP20220928T1 (en)	2022-10-28
BR112014008815A2 (en)	2017-04-25
PL2766367T3 (en)	2022-08-22
CA2850439A1 (en)	2013-04-18
JP6071012B2 (en)	2017-02-01
US9790225B2 (en)	2017-10-17
BR112014008815B1 (en)	2021-01-12
JP2014528468A (en)	2014-10-27
CA2850439C (en)	2020-04-07
NZ623573A (en)	2016-08-26
MX2014003987A (en)	2014-09-22
IL231934A (en)	2017-03-30
LT2766367T (en)	2022-08-25
DK2766367T3 (en)	2022-08-01
ZA201402226B (en)	2015-05-27
KR20140095467A (en)	2014-08-01
CN103946224A (en)	2014-07-23
RU2014118953A (en)	2015-11-20
EP2766367A1 (en)	2014-08-20
PT2766367T (en)	2022-08-12
SG11201401351PA (en)	2014-08-28
HUE059217T2 (en)	2022-10-28

Publication	Publication Date	Title
IL257410A (en)	2018-04-30	Pyrazolo [1, 5 -a] pyrimidines as antiviral agents
EP2751112A4 (en)	2015-04-01	Substituted pyrazolo[3,4-d]pyrimidines and uses thereof
PT2794611T (en)	2017-12-06	Pyrazolo[1,5-a]pyrimidines as antiviral agents
IL227526A0 (en)	2013-09-30	6-cyclobutyl-1,5-dihydro-pyrazolo [3,4-d]pyrimidin-4-one derivatives their use as pde9a inhibitors
HK1176236A1 (en)	2013-07-26	Thiazolo[5,4-d] pyrimidines and their use as agrochemicals [54-d]
IL229606A0 (en)	2014-01-30	Pyrazolo [3,4-d] pyrimidine compounds and their use as pde2 inhibitors and/or cyp3a4 inhibitors
AP2012006631A0 (en)	2012-12-31	6-Cycloalkyl-1, 5-dihydro-pyrazolo[3,4-D] pyrimidin-4-one derivatives and their use as PDE9A inhibitors
ZA201403441B (en)	2015-08-26	[1,2,3]triazolo[4,5-d]pyrimidine derivatives as agonists of the cannabinoid
ZA201406323B (en)	2016-08-31	Triazolo[4,5-d]pyrimidine derivatives
PT2920174T (en)	2016-12-23	Substituted pyrazolo[3,4-d]pyrimidine compounds, their preparation and use as sigma receptors ligands
HK1193806A1 (en)	2014-10-03	Thieno[2,3-d]pyrimidine derivatives and their use to treat arrhythmia [23-d]
SG10201602846TA (en)	2016-05-30	4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives, their manufacture and use as antiviral agents