SG10201600077RA - Combination - Google Patents

Combination

Info

Publication number
SG10201600077RA
SG10201600077RA SG10201600077RA SG10201600077RA SG10201600077RA SG 10201600077R A SG10201600077R A SG 10201600077RA SG 10201600077R A SG10201600077R A SG 10201600077RA SG 10201600077R A SG10201600077R A SG 10201600077RA SG 10201600077R A SG10201600077R A SG 10201600077RA
Authority
SG
Singapore
Prior art keywords
combination
Prior art date
Application number
SG10201600077RA
Inventor
Rakesh Kumar
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of SG10201600077RA publication Critical patent/SG10201600077RA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • A61K31/41551,2-Diazoles non condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/005Enzyme inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
SG10201600077RA 2011-01-11 2012-01-11 Combination SG10201600077RA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161431508P 2011-01-11 2011-01-11

Publications (1)

Publication Number Publication Date
SG10201600077RA true SG10201600077RA (en) 2016-02-26

Family

ID=46507420

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201600077RA SG10201600077RA (en) 2011-01-11 2012-01-11 Combination
SG2013043856A SG191724A1 (en) 2011-01-11 2012-01-11 Combination

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG2013043856A SG191724A1 (en) 2011-01-11 2012-01-11 Combination

Country Status (15)

Country Link
US (6) US20130288984A1 (en)
EP (1) EP2663189B1 (en)
JP (1) JP6100700B2 (en)
KR (1) KR20140053836A (en)
CN (1) CN103298345B (en)
AU (1) AU2012205601B2 (en)
BR (1) BR112013017722A2 (en)
CA (1) CA2824201A1 (en)
EA (1) EA029000B1 (en)
ES (1) ES2689760T3 (en)
IL (1) IL227097B (en)
MX (1) MX356704B (en)
SG (2) SG10201600077RA (en)
WO (1) WO2012097021A1 (en)
ZA (1) ZA201304139B (en)

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* Cited by examiner, † Cited by third party
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CA2925374A1 (en) * 2013-10-01 2015-04-09 Novartis Ag Combination
JP6568093B2 (en) * 2013-11-07 2019-08-28 デシフェラ ファーマシューティカルズ,エルエルシー Method of inhibiting TIE2 kinase useful for cancer treatment
WO2021030405A1 (en) 2019-08-12 2021-02-18 Deciphera Pharmaceuticals, Llc Ripretinib for treating gastrointestinal stromal tumors
MX2022001863A (en) 2019-08-12 2022-05-30 Deciphera Pharmaceuticals Llc Ripretinib for treating gastrointestinal stromal tumors.
MX2022008103A (en) 2019-12-30 2022-09-19 Deciphera Pharmaceuticals Llc Amorphous kinase inhibitor formulations and methods of use thereof.
KR20220123058A (en) 2019-12-30 2022-09-05 데시페라 파마슈티칼스, 엘엘씨. 1-(4-Bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl ) -3-Phenylurea composition
US11779572B1 (en) 2022-09-02 2023-10-10 Deciphera Pharmaceuticals, Llc Methods of treating gastrointestinal stromal tumors

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US7468371B2 (en) * 2004-03-24 2008-12-23 Abbott Laboratories Inc. Tricyclic pyrazole kinase inhibitors
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US7709517B2 (en) 2005-05-13 2010-05-04 The Regents Of The University Of California Diarylhydantoin compounds
EP1928437A2 (en) * 2005-08-26 2008-06-11 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP1840114A1 (en) 2006-03-30 2007-10-03 LTB4 Sweden AB Crystalline Leukotriene B4
EP2004165A2 (en) 2006-04-05 2008-12-24 Novartis Pharma AG Synergistic combinations of anticancer agents for treating cancer
WO2007122686A1 (en) 2006-04-14 2007-11-01 Eisai R & D Management Co., Ltd. Benzimidazole compounds
US20080051380A1 (en) 2006-08-25 2008-02-28 Auerbach Alan H Methods and compositions for treating cancer
ES2428634T3 (en) 2006-08-25 2013-11-08 Janssen Oncology, Inc. Compositions for cancer treatment
JP4299327B2 (en) 2006-08-31 2009-07-22 トヨタ自動車株式会社 Variable valve timing device
US8828451B2 (en) 2006-10-04 2014-09-09 University Of South Florida Akt sensitization of cancer cells
EP2079714B1 (en) 2006-10-13 2012-09-26 Basf Se Hydrates of 2-chloro-5-ý3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoro-methyl)-1-(2h)-pyrimidinyl¨-4-fluoro-n-ýýmethyl-(1-methylethyl)-amino¨sulphonyl¨benzamide
AR064010A1 (en) * 2006-12-06 2009-03-04 Merck & Co Inc AKT ACTIVITY INHIBITORS
UY30892A1 (en) 2007-02-07 2008-09-02 Smithkline Beckman Corp AKT ACTIVITY INHIBITORS
KR101494734B1 (en) 2007-10-11 2015-02-26 아스트라제네카 아베 Pyrrolo[ 2,3-d] pyrimidin derivatives as protein kinase b inhibitors
US20090131367A1 (en) * 2007-11-19 2009-05-21 The Regents Of The University Of Colorado Combinations of HDAC Inhibitors and Proteasome Inhibitors
DE102008044901A1 (en) 2008-08-29 2010-03-04 Siemens Aktiengesellschaft Method and device for selecting an irradiation plan and irradiation facility
PE20120003A1 (en) 2009-01-30 2012-02-12 Glaxosmithkline Llc N - {(1S) -2-AMINO-1 - [(3-FLUOROPHENYL) METHYL) ETHYL HYDROCHLORIDE} -5-CHLORO-4- (4-CHLORO-1-METHYL-1H-PIRAZOL-5-IL) - CRYSTALLINE 2-THIOPHENOCARBOXAMIDE
SG176105A1 (en) 2009-06-26 2011-12-29 Novartis Ag 1, 3-disubstituted imidazolidin-2-one derivatives as inhibitors of cyp 17
ES2530436T3 (en) 2009-10-08 2015-03-02 Glaxosmithkline Llc Combination
ES2657750T3 (en) 2011-04-01 2018-03-06 Genentech, Inc. Combination of AKT inhibitor compound and vemurafenib for use in therapeutic treatments
EP2704699A1 (en) 2011-05-03 2014-03-12 University of Rochester Methods for treating prostate cancer
KR20140048968A (en) 2011-07-13 2014-04-24 파마시클릭스, 인코포레이티드 Inhibitors of bruton's tyrosine kinase
WO2013053691A1 (en) 2011-10-10 2013-04-18 Zach System Process for preparing 17-substituted steroids
LT2785349T (en) 2011-11-30 2019-12-10 Astrazeneca Ab Combination treatment of cancer
KR20220093389A (en) 2012-06-04 2022-07-05 파마싸이클릭스 엘엘씨 Crystalline forms of a bruton's tyrosine kinase inhibitor
JP6355724B2 (en) 2013-10-01 2018-07-11 ノバルティス アーゲー Enzalutamide in combination with afreseltiv to treat cancer

Also Published As

Publication number Publication date
US10449226B2 (en) 2019-10-22
WO2012097021A1 (en) 2012-07-19
CN103298345B (en) 2016-12-14
SG191724A1 (en) 2013-08-30
EP2663189B1 (en) 2018-07-04
US20150119337A1 (en) 2015-04-30
MX356704B (en) 2018-06-11
ZA201304139B (en) 2014-02-26
MX2013008074A (en) 2013-08-09
US20120258933A1 (en) 2012-10-11
EP2663189A4 (en) 2014-06-11
AU2012205601B2 (en) 2016-03-24
US20130288984A1 (en) 2013-10-31
EP2663189A1 (en) 2013-11-20
ES2689760T3 (en) 2018-11-15
CN103298345A (en) 2013-09-11
IL227097B (en) 2018-02-28
AU2012205601A1 (en) 2013-08-01
JP2014507412A (en) 2014-03-27
JP6100700B2 (en) 2017-03-22
US20170100449A1 (en) 2017-04-13
US20160375086A1 (en) 2016-12-29
US20160022641A1 (en) 2016-01-28
EA201391027A1 (en) 2014-01-30
BR112013017722A2 (en) 2016-07-12
KR20140053836A (en) 2014-05-08
EA029000B1 (en) 2018-01-31
CA2824201A1 (en) 2012-07-19

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