SG10201501780QA - Method of purifying influenza virus and removing mdck cell dna contaminants - Google Patents
Method of purifying influenza virus and removing mdck cell dna contaminantsInfo
- Publication number
- SG10201501780QA SG10201501780QA SG10201501780QA SG10201501780QA SG10201501780QA SG 10201501780Q A SG10201501780Q A SG 10201501780QA SG 10201501780Q A SG10201501780Q A SG 10201501780QA SG 10201501780Q A SG10201501780Q A SG 10201501780QA SG 10201501780Q A SG10201501780Q A SG 10201501780QA
- Authority
- SG
- Singapore
- Prior art keywords
- influenza virus
- cell dna
- mdck cell
- dna contaminants
- purifying influenza
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16151—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16151—Methods of production or purification of viral material
- C12N2760/16152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16251—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16251—Methods of production or purification of viral material
- C12N2760/16252—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84512106P | 2006-09-15 | 2006-09-15 | |
| US87172106P | 2006-12-22 | 2006-12-22 | |
| US91700807P | 2007-05-09 | 2007-05-09 | |
| US95181307P | 2007-07-25 | 2007-07-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201501780QA true SG10201501780QA (en) | 2015-04-29 |
Family
ID=39721761
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201501780QA SG10201501780QA (en) | 2006-09-15 | 2007-09-14 | Method of purifying influenza virus and removing mdck cell dna contaminants |
| SG2011066164A SG174813A1 (en) | 2006-09-15 | 2007-09-14 | Mdck cell lines supporting viral growth to high titers and bioreactor process using the same |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2011066164A SG174813A1 (en) | 2006-09-15 | 2007-09-14 | Mdck cell lines supporting viral growth to high titers and bioreactor process using the same |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20080286850A1 (en) |
| EP (2) | EP2069480B1 (en) |
| JP (2) | JP5260525B2 (en) |
| KR (2) | KR101464783B1 (en) |
| CN (2) | CN101627113B (en) |
| AU (1) | AU2007347716B2 (en) |
| BR (1) | BRPI0716724A2 (en) |
| CA (1) | CA2663522C (en) |
| ES (1) | ES2473275T3 (en) |
| MX (1) | MX2009002741A (en) |
| RU (2) | RU2487935C2 (en) |
| SG (2) | SG10201501780QA (en) |
| WO (1) | WO2008105931A2 (en) |
Families Citing this family (49)
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| ES2526170T3 (en) | 2004-12-23 | 2015-01-07 | Medimmune, Llc | MDCK non-tumorigenic cell line to spread virus |
| EP2010557B1 (en) | 2006-03-31 | 2014-02-26 | Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses for vaccines |
| US20080286850A1 (en) | 2006-09-15 | 2008-11-20 | Medimmune Vaccines, Inc. | Mdck cell lines supporting viral growth to high titers and bioreactor process using the same |
| US9474798B2 (en) | 2007-06-18 | 2016-10-25 | Wisconsin Alumni Research Foundation | Influenza M2 protein mutant viruses as live influenza attenuated vaccines |
| KR20110074563A (en) | 2008-09-24 | 2011-06-30 | 메디뮨 엘엘씨 | Methods for purification of viruses |
| CA2738022A1 (en) * | 2008-09-24 | 2010-04-01 | Medimmune, Llc | Methods for cultivating cells, propagating and purifying viruses |
| WO2010052214A2 (en) * | 2008-11-05 | 2010-05-14 | Glaxosmithkline Biologicals S.A. | Novel method |
| JP2010143860A (en) * | 2008-12-19 | 2010-07-01 | Chisso Corp | Protein stabilizer |
| ES2813347T3 (en) | 2009-10-26 | 2021-03-23 | Wisconsin Alumni Res Found | Recombinant High Titer Influenza Viruses with Enhanced Replication in Vero Cells |
| US10130697B2 (en) | 2010-03-23 | 2018-11-20 | Wisconsin Alumni Research Foundation (Warf) | Vaccines comprising mutant attenuated influenza viruses |
| US20110262965A1 (en) * | 2010-04-23 | 2011-10-27 | Life Technologies Corporation | Cell culture medium comprising small peptides |
| WO2011135393A1 (en) * | 2010-04-27 | 2011-11-03 | Universidad Manuela Beltran | Autologous biological cancer vaccine |
| TW201202425A (en) * | 2010-04-28 | 2012-01-16 | Abbott Biologicals Bv | Production of viral components |
| EP2606128B1 (en) * | 2010-08-16 | 2014-09-10 | CEVEC Pharmaceuticals GmbH | Permanent human amniocytic cell line for the production of influenza virus |
| CN101979517B (en) * | 2010-10-15 | 2011-12-28 | 普莱柯生物工程股份有限公司 | Method for producing influenza viruses in large scale by using bioreactor |
| US9365832B2 (en) | 2012-01-09 | 2016-06-14 | Sanofi Pasteur Biologics, Llc | Purification of herpes virus |
| CN102526720B (en) * | 2012-01-11 | 2013-12-11 | 中国人民解放军军事医学科学院微生物流行病研究所 | Preparation method of influenza virus vaccine |
| JP6152535B2 (en) * | 2012-04-16 | 2017-06-28 | 公益財団法人ヒューマンサイエンス振興財団 | Cell culture composition and method for producing influenza virus |
| US11260123B2 (en) | 2012-05-21 | 2022-03-01 | Sanofi Pasteur Limited | Herpesvirus compositions and related methods |
| RU2507255C1 (en) * | 2012-07-23 | 2014-02-20 | Государственное научное учреждение Всероссийский научно-исследовательский институт ветеринарной вирусологии и микробиологии Россельхозакадемии | STRAIN OF DIPLOID CELLS OF LAMB SYNOVIAL MEMBRANE Ovis aries USED FOR VIROLOGICAL INVESTIGATIONS |
| RU2506310C1 (en) * | 2012-07-23 | 2014-02-10 | Государственное научное учреждение Всероссийский научно-исследовательский институт ветеринарной вирусологии и микробиологии Россельхозакадемии | STRAIN OF DIPLOID CELLS OF SYNOVIAL MEMBRANE OF YOUNG PIG Sus scrofa, USED FOR VIROLOGY RESEARCH |
| MY173223A (en) | 2012-12-28 | 2020-01-07 | Boehringer Ingelheim Vetmedica Gmbh | Method of making a mycoplasma vaccine |
| KR102355614B1 (en) | 2012-12-28 | 2022-01-27 | 베링거잉겔하임베트메디카게엠베하 | Immunogenic composition comprising mycoplasma antigens |
| KR101370512B1 (en) | 2013-06-07 | 2014-03-06 | 재단법인 목암생명공학연구소 | Mdck-derived cell lines suspension-cultured in a protein-free medium and method for propagating virus using the same |
| US9950057B2 (en) | 2013-07-15 | 2018-04-24 | Wisconsin Alumni Research Foundation (Warf) | High titer recombinant influenza viruses with enhanced replication in MDCK or vero cells or eggs |
| JP2014088409A (en) * | 2013-12-20 | 2014-05-15 | Jnc Corp | Protein stabilizer |
| US10053671B2 (en) | 2014-06-20 | 2018-08-21 | Wisconsin Alumni Research Foundation (Warf) | Mutations that confer genetic stability to additional genes in influenza viruses |
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| RU2573938C1 (en) * | 2014-12-11 | 2016-01-27 | Федеральное государственное бюджетное учреждение науки Институт биологии гена Российской академии наук | Cell line of human kidney cancer ibgvat r 27 |
| CN104689311A (en) * | 2014-12-31 | 2015-06-10 | 瑞普（保定）生物药业有限公司 | Method for producing avian encephalomyelitis virus inactivated vaccine |
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| EP3438247A4 (en) * | 2016-03-29 | 2019-12-04 | The Research Foundation for Microbial Diseases of Osaka University | Method for culturing mdck cells |
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| JP4629385B2 (en) * | 2004-08-16 | 2011-02-09 | Ｎｔｎ株式会社 | Needle roller bearing |
| KR101376889B1 (en) | 2004-10-06 | 2014-03-25 | 메디뮨 엘엘씨 | Refrigerator-temperature stable influenza vaccine compositions |
| EP2573186A1 (en) | 2004-12-08 | 2013-03-27 | MedImmune, LLC | Methods of producing influenza vaccine compositions |
| ES2526170T3 (en) | 2004-12-23 | 2015-01-07 | Medimmune, Llc | MDCK non-tumorigenic cell line to spread virus |
| EP1862537B1 (en) | 2005-03-10 | 2013-05-08 | Kyoritsu Seiyaku Corporation | Cell line culturable without aminal-derived component, method for establishment thereof, method for production of virus using the cell line and method for production of vaccine |
| US7534596B2 (en) * | 2006-02-10 | 2009-05-19 | Solohill Engineering, Inc. | Method and device for producing vaccine |
| JP5129805B2 (en) | 2006-04-20 | 2013-01-30 | ワイス・エルエルシー | Purification process for isolation of purified vesicular stomatitis virus from cell culture |
| WO2007130327A2 (en) | 2006-05-01 | 2007-11-15 | Technovax, Inc. | Influenza virus-like particle (vlp) compositions |
| US20080286850A1 (en) | 2006-09-15 | 2008-11-20 | Medimmune Vaccines, Inc. | Mdck cell lines supporting viral growth to high titers and bioreactor process using the same |
| EP1982727A1 (en) | 2007-04-17 | 2008-10-22 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Method for purification of viral proteins |
| KR20110074563A (en) | 2008-09-24 | 2011-06-30 | 메디뮨 엘엘씨 | Methods for purification of viruses |
| CA2738022A1 (en) * | 2008-09-24 | 2010-04-01 | Medimmune, Llc | Methods for cultivating cells, propagating and purifying viruses |
-
2007
- 2007-09-14 US US11/855,769 patent/US20080286850A1/en not_active Abandoned
- 2007-09-14 KR KR1020097007751A patent/KR101464783B1/en active IP Right Grant
- 2007-09-14 WO PCT/US2007/078527 patent/WO2008105931A2/en active Application Filing
- 2007-09-14 ES ES07873789.7T patent/ES2473275T3/en active Active
- 2007-09-14 BR BRPI0716724-5A2A patent/BRPI0716724A2/en not_active IP Right Cessation
- 2007-09-14 AU AU2007347716A patent/AU2007347716B2/en not_active Ceased
- 2007-09-14 JP JP2009528504A patent/JP5260525B2/en not_active Expired - Fee Related
- 2007-09-14 EP EP07873789.7A patent/EP2069480B1/en not_active Not-in-force
- 2007-09-14 SG SG10201501780QA patent/SG10201501780QA/en unknown
- 2007-09-14 RU RU2009113671/10A patent/RU2487935C2/en not_active IP Right Cessation
- 2007-09-14 KR KR1020147015024A patent/KR20140075022A/en not_active Application Discontinuation
- 2007-09-14 CA CA2663522A patent/CA2663522C/en not_active Expired - Fee Related
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- 2007-09-14 CN CN2007800423659A patent/CN101627113B/en not_active Expired - Fee Related
- 2007-09-14 SG SG2011066164A patent/SG174813A1/en unknown
- 2007-09-14 CN CN2013101052598A patent/CN103361319A/en active Pending
- 2007-09-14 EP EP13163566.6A patent/EP2615167A1/en not_active Withdrawn
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2010
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2012
- 2012-08-27 US US13/595,897 patent/US8846032B2/en active Active
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2013
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Also Published As
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|---|---|
| BRPI0716724A2 (en) | 2013-10-01 |
| JP2010503412A (en) | 2010-02-04 |
| CN103361319A (en) | 2013-10-23 |
| KR20140075022A (en) | 2014-06-18 |
| AU2007347716B2 (en) | 2013-06-20 |
| AU2007347716A1 (en) | 2008-09-04 |
| KR101464783B1 (en) | 2014-11-26 |
| US20080286850A1 (en) | 2008-11-20 |
| US8357376B2 (en) | 2013-01-22 |
| US20100112669A1 (en) | 2010-05-06 |
| RU2487935C2 (en) | 2013-07-20 |
| ES2473275T3 (en) | 2014-07-04 |
| RU2012145173A (en) | 2014-04-27 |
| EP2615167A1 (en) | 2013-07-17 |
| JP2013153762A (en) | 2013-08-15 |
| EP2069480B1 (en) | 2014-03-19 |
| US8846032B2 (en) | 2014-09-30 |
| EP2069480A4 (en) | 2011-03-30 |
| EP2069480A2 (en) | 2009-06-17 |
| CA2663522C (en) | 2015-06-02 |
| KR20090057444A (en) | 2009-06-05 |
| CN101627113B (en) | 2013-04-24 |
| MX2009002741A (en) | 2009-05-11 |
| US20130052717A1 (en) | 2013-02-28 |
| CA2663522A1 (en) | 2008-09-04 |
| RU2009113671A (en) | 2010-10-20 |
| CN101627113A (en) | 2010-01-13 |
| SG174813A1 (en) | 2011-10-28 |
| WO2008105931A3 (en) | 2009-02-19 |
| WO2008105931A2 (en) | 2008-09-04 |
| JP5260525B2 (en) | 2013-08-14 |
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