SG10201408483QA - Progesterone antagonists such as cdb-4124 in the treatment of endometriosis, uterine fibroids, dysmenorrhea, breast cancer etc - Google Patents

Progesterone antagonists such as cdb-4124 in the treatment of endometriosis, uterine fibroids, dysmenorrhea, breast cancer etc

Info

Publication number: SG10201408483QA
Authority: SG; Singapore
Prior art keywords: cdb; dysmenorrhea; endometriosis; treatment; breast cancer
Prior art date: 2008-04-28

Application number

SG10201408483QA

Inventor

Joseph S Podolski

Original Assignee

Repros Therapeutics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-04-28

Filing date

2009-04-27

Publication date

2015-02-27

2009-04-27 Application filed by Repros Therapeutics Inc filed Critical Repros Therapeutics Inc

2015-02-27 Publication of SG10201408483QA publication Critical patent/SG10201408483QA/en

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Reproductive Health (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Steroid Compounds (AREA)

SG10201408483QA 2008-04-28 2009-04-27 Progesterone antagonists such as cdb-4124 in the treatment of endometriosis, uterine fibroids, dysmenorrhea, breast cancer etc SG10201408483QA (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US4847208P	2008-04-28	2008-04-28

Publications (1)

Publication Number	Publication Date
SG10201408483QA true SG10201408483QA (en)	2015-02-27

Family

ID=40751037

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG10201408483QA SG10201408483QA (en)	2008-04-28	2009-04-27	Progesterone antagonists such as cdb-4124 in the treatment of endometriosis, uterine fibroids, dysmenorrhea, breast cancer etc

Country Status (24)

Country	Link
US (2)	US8426394B2 (en)
EP (1)	EP2293797B1 (en)
JP (1)	JP5791499B2 (en)
KR (2)	KR20130059442A (en)
CN (2)	CN105616427A (en)
AR (1)	AR071516A1 (en)
AU (1)	AU2009241355B2 (en)
BR (1)	BRPI0911563A2 (en)
CA (1)	CA2722753C (en)
CL (1)	CL2009001010A1 (en)
DK (1)	DK2293797T3 (en)
EA (3)	EA032646B1 (en)
ES (1)	ES2561810T3 (en)
IL (1)	IL208844A0 (en)
ME (1)	ME01123B (en)
MX (1)	MX2010011272A (en)
MY (1)	MY161059A (en)
NI (1)	NI201000183A (en)
NZ (1)	NZ589533A (en)
SG (1)	SG10201408483QA (en)
TW (1)	TWI477276B (en)
UA (1)	UA102849C2 (en)
WO (1)	WO2009134718A1 (en)
ZA (1)	ZA201007529B (en)

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UA113283C2 (en) *	2010-12-23	2017-01-10		19-NORSTEROIDS AND THEIR APPLICATIONS FOR THE TREATMENT OF PROGESTERON-STAINLESS STATES
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NZ702467A (en) *	2012-05-31	2016-07-29	Repros Therapeutics Inc	Formulations and methods for vaginal delivery of antiprogestins
US10806740B2 (en)	2012-06-18	2020-10-20	Therapeuticsmd, Inc.	Natural combination hormone replacement formulations and therapies
US20130338122A1 (en)	2012-06-18	2013-12-19	Therapeuticsmd, Inc.	Transdermal hormone replacement therapies
US10806697B2 (en)	2012-12-21	2020-10-20	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en)	2012-06-18	2015-07-16	Therapeuticsmd, Inc.	Progesterone formulations having a desirable pk profile
ES2688821T3 (en) *	2012-11-02	2018-11-07	Repros Therapeutics Inc.	Methods and compositions to treat progesterone-dependent conditions
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US10471072B2 (en)	2012-12-21	2019-11-12	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en)	2012-12-21	2022-03-08	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en)	2012-12-21	2020-01-21	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en)	2012-12-21	2022-02-15	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en)	2012-12-21	2020-02-25	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
HU230381B1 (en) *	2014-02-17	2016-03-29	Richter Gedeon Nyrt	Process for producing steroid intermediate
RU2016143081A (en)	2014-05-22	2018-06-26	Терапьютиксмд, Инк.	NATURAL COMBINED HORMONE SUBSTITUTION COMPOSITIONS AND THERAPIES
KR20170040209A (en)	2014-07-29	2017-04-12	쎄러퓨틱스엠디, 인코퍼레이티드	Transdermal cream
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2009
- 2009-04-09 TW TW098111780A patent/TWI477276B/en not_active IP Right Cessation
- 2009-04-27 MY MYPI2010004777A patent/MY161059A/en unknown
- 2009-04-27 SG SG10201408483QA patent/SG10201408483QA/en unknown
- 2009-04-27 EA EA201401347A patent/EA032646B1/en not_active IP Right Cessation
- 2009-04-27 EA EA201071249A patent/EA201071249A1/en unknown
- 2009-04-27 KR KR1020137009925A patent/KR20130059442A/en active Search and Examination
- 2009-04-27 EA EA201990835A patent/EA201990835A3/en unknown
- 2009-04-27 DK DK09739520.6T patent/DK2293797T3/en active
- 2009-04-27 BR BRPI0911563A patent/BRPI0911563A2/en not_active Application Discontinuation
- 2009-04-27 MX MX2010011272A patent/MX2010011272A/en active IP Right Grant
- 2009-04-27 ES ES09739520.6T patent/ES2561810T3/en active Active
- 2009-04-27 CN CN201610029200.9A patent/CN105616427A/en active Pending
- 2009-04-27 EP EP09739520.6A patent/EP2293797B1/en active Active
- 2009-04-27 CN CN2009801149788A patent/CN102014923A/en active Pending
- 2009-04-27 AU AU2009241355A patent/AU2009241355B2/en not_active Ceased
- 2009-04-27 JP JP2011506497A patent/JP5791499B2/en not_active Expired - Fee Related
- 2009-04-27 KR KR20107026587A patent/KR20110014162A/en not_active Application Discontinuation
- 2009-04-27 ME MEP-2010-182A patent/ME01123B/en unknown
- 2009-04-27 UA UAA201014039A patent/UA102849C2/en unknown
- 2009-04-27 US US12/990,203 patent/US8426394B2/en active Active
- 2009-04-27 WO PCT/US2009/041826 patent/WO2009134718A1/en active Application Filing
- 2009-04-27 CA CA2722753A patent/CA2722753C/en not_active Expired - Fee Related
- 2009-04-27 NZ NZ589533A patent/NZ589533A/en not_active IP Right Cessation
- 2009-04-28 CL CL2009001010A patent/CL2009001010A1/en unknown
- 2009-04-28 AR ARP090101513 patent/AR071516A1/en unknown
2010
- 2010-10-20 IL IL208844A patent/IL208844A0/en unknown
- 2010-10-21 ZA ZA2010/07529A patent/ZA201007529B/en unknown
- 2010-10-27 NI NI201000183A patent/NI201000183A/en unknown
2013
- 2013-04-02 US US13/855,559 patent/US8735381B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP2011518845A (en)	2011-06-30
ZA201007529B (en)	2011-07-27
KR20110014162A (en)	2011-02-10
WO2009134718A8 (en)	2010-09-23
US20130289008A1 (en)	2013-10-31
EA201401347A1 (en)	2015-07-30
JP5791499B2 (en)	2015-10-07
US8426394B2 (en)	2013-04-23
CN105616427A (en)	2016-06-01
AR071516A1 (en)	2010-06-23
KR20130059442A (en)	2013-06-05
IL208844A0 (en)	2011-01-31
MX2010011272A (en)	2010-12-21
DK2293797T3 (en)	2016-01-11
EA032646B1 (en)	2019-06-28
BRPI0911563A2 (en)	2016-07-12
CA2722753A1 (en)	2009-11-05
MY161059A (en)	2017-04-14
UA102849C2 (en)	2013-08-27
US8735381B2 (en)	2014-05-27
EA201990835A2 (en)	2019-08-30
NZ589533A (en)	2012-06-29
TW200950786A (en)	2009-12-16
EA201990835A3 (en)	2019-12-30
TWI477276B (en)	2015-03-21
CL2009001010A1 (en)	2009-06-19
CN102014923A (en)	2011-04-13
US20110046098A1 (en)	2011-02-24
EA201071249A1 (en)	2011-08-30
EP2293797B1 (en)	2015-11-11
EP2293797A1 (en)	2011-03-16
AU2009241355A1 (en)	2009-11-05
ME01123B (en)	2013-03-20
CA2722753C (en)	2018-07-03
WO2009134718A1 (en)	2009-11-05
ES2561810T3 (en)	2016-03-01
NI201000183A (en)	2012-06-06
AU2009241355B2 (en)	2013-11-14

Publication	Publication Date	Title
IL208844A0 (en)	2011-01-31	Progesterone antagonists such as cdb-4124 in the treatment of endometriosis, uterine fibroids, dysmenorrhea, breast cancer, etc
IL247093A0 (en)	2016-09-29	Progesterone antagonists such as cdb-4124 in the treatment of breast cancer
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GB0802486D0 (en)	2008-03-19	Warm water economy device
ZA201006049B (en)	2011-05-25	Use of ulipristal for treating uterine fibroids
PL2451328T3 (en)	2013-03-29	Mixing device
SI2376020T1 (en)	2017-07-31	Vaginal device
EP2350255A4 (en)	2013-07-31	Polyaluminum compositions
GB0810252D0 (en)	2008-07-09	Device for preparing bone cement
PT2482841T (en)	2019-03-01	Compositions and methods for enhancing coagulation factor viii function
IL200764A (en)	2017-01-31	Composition comprising epha3 antibodies for use in the treatment of solid tumors
GB0807555D0 (en)	2008-06-04	Two-chamber coaxial electrolyser device
EP2493291A4 (en)	2013-08-21	Peham dendrimers for use in agriculture
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