SG10201401280TA - Anti-TGF-Beta Receptor II Antibodies - Google Patents

Anti-TGF-Beta Receptor II Antibodies

Info

Publication number: SG10201401280TA
Authority: SG; Singapore
Prior art keywords: tgf; antibodies; beta receptor; receptor; beta
Prior art date: 2008-11-07

Application number

SG10201401280TA

Inventor

Yan Wu

Original Assignee

Imclone Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-11-07

Filing date

2009-10-29

Publication date

2014-05-29

2009-10-29 Application filed by Imclone Llc filed Critical Imclone Llc

2014-05-29 Publication of SG10201401280TA publication Critical patent/SG10201401280TA/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

SG10201401280TA 2008-11-07 2009-10-29 Anti-TGF-Beta Receptor II Antibodies SG10201401280TA (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US19869708P	2008-11-07	2008-11-07
US17036909P	2009-04-17	2009-04-17

Publications (1)

Publication Number	Publication Date
SG10201401280TA true SG10201401280TA (en)	2014-05-29

Family

ID=41508691

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG10201401280TA SG10201401280TA (en)	2008-11-07	2009-10-29	Anti-TGF-Beta Receptor II Antibodies

Country Status (19)

Country	Link
US (2)	US8147834B2 (en)
EP (1)	EP2356152A1 (en)
JP (1)	JP5667067B2 (en)
KR (1)	KR101283856B1 (en)
CN (1)	CN102209727B (en)
AR (1)	AR073909A1 (en)
AU (1)	AU2009311375B2 (en)
BR (1)	BRPI0921263A2 (en)
CA (1)	CA2742961C (en)
EA (1)	EA025169B1 (en)
IL (1)	IL211842A (en)
JO (1)	JO3096B1 (en)
MX (1)	MX2011004871A (en)
NZ (1)	NZ591943A (en)
PA (1)	PA8846101A1 (en)
SG (1)	SG10201401280TA (en)
TW (1)	TWI384998B (en)
WO (1)	WO2010053814A1 (en)
ZA (1)	ZA201103178B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MA34820B1 (en) *	2011-01-06	2014-01-02	Glaxo Group Ltd	LIGANDISE BINDING TO TGF-BETA RECEPTOR II
AR086044A1 (en)	2011-05-12	2013-11-13	Imclone Llc	ANTIBODIES THAT SPECIFICALLY JOIN A C-KIT EXTRACELLULAR DOMAIN AND USES OF THE SAME
CA2975147A1 (en)	2015-01-31	2016-08-04	Yangbing Zhao	Compositions and methods for t cell delivery of therapeutic molecules
BR112018008891A8 (en)	2015-11-03	2019-02-26	Janssen Biotech Inc	antibodies that specifically bind to pd-1 and tim-3 and their uses
CN109071646A (en)	2016-03-11	2018-12-21	供石公司	TGF β 1- binding domain-immunoglobulin and application thereof
AR109770A1 (en)	2016-10-18	2019-01-23	Lilly Co Eli	TGF-b RECEIVER II ANTIBODIES
CN106884005A (en) *	2017-01-19	2017-06-23	樊克兴	A kind of preparation method of colorectal cancer T cells with antigenic specificity
JP7280254B2 (en)	2017-10-24	2023-05-23	マジェンタセラピューティクスインコーポレイテッド	Compositions and methods for depleting CD117+ cells
US10882915B2 (en)	2017-10-24	2021-01-05	Magenta Therapeutics, Inc.	Compositions and methods for the depletion of CD117+ cells
WO2019084053A1 (en) *	2017-10-24	2019-05-02	Magenta Therapeutics, Inc.	Compositions and methods for the depletion of cd117+ cells
CN107973853B (en) *	2017-12-12	2021-04-30	山西农业大学	Method for preparing Smad2 protein specific antibody by using characteristic polypeptide and application thereof
EP4081306A1 (en)	2019-12-24	2022-11-02	Merus N.V.	Tgf-beta-rii binding proteins
KR102314157B1 (en) *	2020-01-10	2021-10-19	주식회사 뉴클릭스바이오	Antibody against transforming growth factor beta receptor and uses thereof
WO2023198194A1 (en) *	2022-04-15	2023-10-19	Biocytogen Pharmaceuticals (Beijing) Co., Ltd.	Anti-cd40 antibodies and uses thereof
CN116178567A (en) *	2022-10-28	2023-05-30	四川大学华西医院	Chimeric antigen receptor targeting TGF beta RII and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5565332A (en)	1991-09-23	1996-10-15	Medical Research Council	Production of chimeric antibodies - a combinatorial approach
EP0610427B1 (en)	1991-10-31	2003-04-02	Whitehead Institute For Biomedical Research	Tgf-beta type iii receptor, cdna encoding it and uses therefor
JP2001206899A (en) *	1999-11-18	2001-07-31	Japan Tobacco Inc	HUMAN MONOCLONAL ANTIBODY AGAINST TGF-beta II TYPE RECEPTOR AND MEDICINAL USE THEREOF
JP2004121001A (en) *	2002-08-07	2004-04-22	Japan Tobacco Inc	HIGH-AFFINITY MONOCLONAL ANTIBODY TO TRANSFORMING GROWTH FACTOR-betaTYPE II RECEPTOR
EP1992360A4 (en)	2006-02-01	2010-02-17	Univ Tokyo	Joint use of tgf-beta signal inhibitor and antitumor agent

2009
- 2009-10-18 JO JOP/2009/0382A patent/JO3096B1/en active
- 2009-10-19 PA PA20098846101A patent/PA8846101A1/en unknown
- 2009-10-19 TW TW098135300A patent/TWI384998B/en not_active IP Right Cessation
- 2009-10-19 AR ARP090104017A patent/AR073909A1/en unknown
- 2009-10-29 KR KR1020117010399A patent/KR101283856B1/en not_active IP Right Cessation
- 2009-10-29 EA EA201170659A patent/EA025169B1/en not_active IP Right Cessation
- 2009-10-29 SG SG10201401280TA patent/SG10201401280TA/en unknown
- 2009-10-29 EP EP09745224A patent/EP2356152A1/en not_active Withdrawn
- 2009-10-29 CN CN200980144391.1A patent/CN102209727B/en not_active Expired - Fee Related
- 2009-10-29 WO PCT/US2009/062450 patent/WO2010053814A1/en active Application Filing
- 2009-10-29 AU AU2009311375A patent/AU2009311375B2/en not_active Ceased
- 2009-10-29 NZ NZ591943A patent/NZ591943A/en not_active IP Right Cessation
- 2009-10-29 JP JP2011534731A patent/JP5667067B2/en not_active Expired - Fee Related
- 2009-10-29 US US12/608,034 patent/US8147834B2/en not_active Expired - Fee Related
- 2009-10-29 BR BRPI0921263-9A patent/BRPI0921263A2/en not_active IP Right Cessation
- 2009-10-29 CA CA2742961A patent/CA2742961C/en not_active Expired - Fee Related
- 2009-10-29 MX MX2011004871A patent/MX2011004871A/en active IP Right Grant
2011
- 2011-03-21 IL IL211842A patent/IL211842A/en not_active IP Right Cessation
- 2011-04-29 ZA ZA2011/03178A patent/ZA201103178B/en unknown
2012
- 2012-02-20 US US13/400,308 patent/US20120177666A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP2356152A1 (en)	2011-08-17
BRPI0921263A2 (en)	2015-08-04
EA025169B1 (en)	2016-11-30
ZA201103178B (en)	2012-10-31
PA8846101A1 (en)	2010-06-28
US8147834B2 (en)	2012-04-03
CN102209727B (en)	2014-07-30
TW201026326A (en)	2010-07-16
TWI384998B (en)	2013-02-11
AU2009311375A1 (en)	2010-05-14
NZ591943A (en)	2012-11-30
KR101283856B1 (en)	2013-07-15
EA201170659A1 (en)	2011-10-31
US20100119516A1 (en)	2010-05-13
IL211842A0 (en)	2011-06-30
CA2742961C (en)	2016-08-30
US20120177666A1 (en)	2012-07-12
CN102209727A (en)	2011-10-05
JP5667067B2 (en)	2015-02-12
IL211842A (en)	2016-09-29
JO3096B1 (en)	2017-03-15
MX2011004871A (en)	2011-07-13
CA2742961A1 (en)	2010-05-14
JP2012508170A (en)	2012-04-05
AR073909A1 (en)	2010-12-09
KR20110067155A (en)	2011-06-21
AU2009311375B2 (en)	2014-07-31
WO2010053814A1 (en)	2010-05-14

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