SE9901059L - Method for making particles - Google Patents
Method for making particlesInfo
- Publication number
- SE9901059L SE9901059L SE9901059A SE9901059A SE9901059L SE 9901059 L SE9901059 L SE 9901059L SE 9901059 A SE9901059 A SE 9901059A SE 9901059 A SE9901059 A SE 9901059A SE 9901059 L SE9901059 L SE 9901059L
- Authority
- SE
- Sweden
- Prior art keywords
- scf
- liquid
- substance
- substance liquid
- particles
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Extraction Or Liquid Replacement (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to a method for the preparation of particles comprising the following steps: the dispersion, with a first supercritical fluid (SCF-D), of a substance liquid at least comprising a mixture of a substance, of which particles are to be prepared, and a liquid carrier medium; and the subsequent extraction, with another supercritical fluid (SCF-E), after the dispersion of the substance liquid, of the liquid carrier medium. An apparatus according to the invention comprises a particle formation reactor (2), the pressure and temperature of which are controllable; means (18, 21) for the delivery of a substance liquid; feeding means (22, 17; 12, 6) for two different supercritical fluids (SCF-D, SCF-E); a nozzle (17) for dispersing the substance liquid; and for feeding of the dispersed substance liquid to the particle formation reactor (2).
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9901059A SE9901059L (en) | 1999-03-22 | 1999-03-22 | Method for making particles |
AU41578/00A AU4157800A (en) | 1999-03-22 | 2000-03-22 | Method for the preparation of particles |
PCT/SE2000/000566 WO2000056439A1 (en) | 1999-03-22 | 2000-03-22 | Method for the preparation of particles |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9901059A SE9901059L (en) | 1999-03-22 | 1999-03-22 | Method for making particles |
Publications (2)
Publication Number | Publication Date |
---|---|
SE9901059D0 SE9901059D0 (en) | 1999-03-22 |
SE9901059L true SE9901059L (en) | 2000-09-23 |
Family
ID=20414970
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9901059A SE9901059L (en) | 1999-03-22 | 1999-03-22 | Method for making particles |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU4157800A (en) |
SE (1) | SE9901059L (en) |
WO (1) | WO2000056439A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW586963B (en) * | 2001-07-20 | 2004-05-11 | Nektar Therapeutics Uk Ltd | Method and apparatus for preparing target substance in particulate form and fluid inlet assembly for said apparatus |
JP5037944B2 (en) * | 2003-10-30 | 2012-10-03 | メルク セローノ ソシエテ アノニム | Method and apparatus for cooling and atomizing liquid or pasty substances |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4568495A (en) * | 1983-05-16 | 1986-02-04 | Union Camp Corporation | Fractionation of polymerized fatty acids |
JPH078202A (en) * | 1993-06-29 | 1995-01-13 | Lion Corp | Production of spice extract |
GB9413202D0 (en) * | 1994-06-30 | 1994-08-24 | Univ Bradford | Method and apparatus for the formation of particles |
GB9703673D0 (en) * | 1997-02-21 | 1997-04-09 | Bradford Particle Design Ltd | Method and apparatus for the formation of particles |
-
1999
- 1999-03-22 SE SE9901059A patent/SE9901059L/en not_active Application Discontinuation
-
2000
- 2000-03-22 AU AU41578/00A patent/AU4157800A/en not_active Abandoned
- 2000-03-22 WO PCT/SE2000/000566 patent/WO2000056439A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2000056439A1 (en) | 2000-09-28 |
AU4157800A (en) | 2000-10-09 |
SE9901059D0 (en) | 1999-03-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
NAV | Patent application has lapsed |
Ref document number: 9901059-7 |