SE9804192D0 - New formulation - Google Patents

New formulation

Info

Publication number
SE9804192D0
SE9804192D0 SE9804192A SE9804192A SE9804192D0 SE 9804192 D0 SE9804192 D0 SE 9804192D0 SE 9804192 A SE9804192 A SE 9804192A SE 9804192 A SE9804192 A SE 9804192A SE 9804192 D0 SE9804192 D0 SE 9804192D0
Authority
SE
Sweden
Prior art keywords
cyclosporin
composition
monoglycerides
lipids
new formulation
Prior art date
Application number
SE9804192A
Other languages
Swedish (sv)
Inventor
Bengt Hersloef
Peter Kaufmann
Carl-Gunnar Kroon
Original Assignee
Scotia Lipidteknik Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scotia Lipidteknik Ab filed Critical Scotia Lipidteknik Ab
Priority to SE9804192A priority Critical patent/SE9804192D0/en
Publication of SE9804192D0 publication Critical patent/SE9804192D0/en
Priority to AU20167/00A priority patent/AU764413B2/en
Priority to JP2000584910A priority patent/JP2002531412A/en
Priority to CA002352388A priority patent/CA2352388A1/en
Priority to NZ512194A priority patent/NZ512194A/en
Priority to PCT/SE1999/002259 priority patent/WO2000032219A1/en
Priority to EP99963798A priority patent/EP1135152A1/en
Priority to HU0105399A priority patent/HUP0105399A3/en
Priority to PL99348062A priority patent/PL348062A1/en
Priority to NO20012736A priority patent/NO20012736L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1274—Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases, cochleates; Sponge phases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Abstract

A pharmaceutical composition comprising a cyclosporin as an active substance in a lipid carrier, which carrier comprises membrane lipids in combination with monoglycerides and optionally non-polar lipids, which composition is characterized in being liquid at room temperature and containing 0.5-25 % cyclosporin, 10-45 % membrane lipids, 10-55 % monoglycerides and 0-45 % non-polar lipids. A composition of the invention is bioequivalent to a commercial drug containing in addition to cyclosporin and additives also toxic emulsifiers and ethanol.
SE9804192A 1998-12-03 1998-12-03 New formulation SE9804192D0 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
SE9804192A SE9804192D0 (en) 1998-12-03 1998-12-03 New formulation
AU20167/00A AU764413B2 (en) 1998-12-03 1999-12-03 A pharmaceutical composition comprising cyclosporin in a lipid carrier
JP2000584910A JP2002531412A (en) 1998-12-03 1999-12-03 Pharmaceutical composition comprising cyclosporin in a lipid carrier
CA002352388A CA2352388A1 (en) 1998-12-03 1999-12-03 A pharmaceutical composition comprising cyclosporin in a lipid carrier
NZ512194A NZ512194A (en) 1998-12-03 1999-12-03 A pharmaceutical composition comprising cyclosporin in a lipid carrier
PCT/SE1999/002259 WO2000032219A1 (en) 1998-12-03 1999-12-03 A pharmaceutical composition comprising cyclosporin in a lipid carrier
EP99963798A EP1135152A1 (en) 1998-12-03 1999-12-03 A pharmaceutical composition comprising cyclosporin in a lipid carrier
HU0105399A HUP0105399A3 (en) 1998-12-03 1999-12-03 Pharmaceutical composition comprising cyclosporin in a lipid carrier
PL99348062A PL348062A1 (en) 1998-12-03 1999-12-03 A pharmaceutical composition comprising cyclosporin in a lipid carrier
NO20012736A NO20012736L (en) 1998-12-03 2001-06-01 Pharmaceutical composition comprising cyclosporin in a lipid carrier

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9804192A SE9804192D0 (en) 1998-12-03 1998-12-03 New formulation

Publications (1)

Publication Number Publication Date
SE9804192D0 true SE9804192D0 (en) 1998-12-03

Family

ID=20413540

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9804192A SE9804192D0 (en) 1998-12-03 1998-12-03 New formulation

Country Status (10)

Country Link
EP (1) EP1135152A1 (en)
JP (1) JP2002531412A (en)
AU (1) AU764413B2 (en)
CA (1) CA2352388A1 (en)
HU (1) HUP0105399A3 (en)
NO (1) NO20012736L (en)
NZ (1) NZ512194A (en)
PL (1) PL348062A1 (en)
SE (1) SE9804192D0 (en)
WO (1) WO2000032219A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0200475D0 (en) * 2002-02-15 2002-02-15 Ltp Lipid Technologies Provide Oral pharmaceutical preparation
US20050058671A1 (en) * 2003-05-09 2005-03-17 Bedding Peter M.J. Dietary supplement and method for treating digestive system-related disorders
SE0303135D0 (en) * 2003-11-25 2003-11-25 Lipocore Holding Ab Controlled food effect composition
SE0401942D0 (en) * 2004-07-28 2004-07-28 Lipopeptide Ab New antimicrobial peptide complexes
AU2006240551A1 (en) * 2005-04-28 2006-11-02 Dsm Ip Assets B.V. Pharmaceutical dosage forms comprising a lipid phase
WO2012144943A1 (en) * 2011-04-18 2012-10-26 Lipidor Ab Liquid carrier for oral delivery of a pharmacologically active agent
WO2014103742A1 (en) * 2012-12-25 2014-07-03 ポーラ化成工業株式会社 Reverse vesicle composition and method for producing same
JP6242581B2 (en) * 2013-04-01 2017-12-06 ポーラ化成工業株式会社 Method for producing reverse vesicle composition
JP6334151B2 (en) * 2012-12-25 2018-05-30 ポーラ化成工業株式会社 Reverse vesicle composition
JP6242582B2 (en) * 2013-04-01 2017-12-06 ポーラ化成工業株式会社 Method for producing reverse vesicle composition

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2222770B (en) * 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
US5529785A (en) * 1993-05-12 1996-06-25 Dietl; Hans Pharmaceutical preparation containing cyclosporin(s) for oral administration and process for producing same
KR100220546B1 (en) * 1994-02-04 1999-09-15 벵 헤르슬로프 Lipophilic carrier preparations
IL129547A (en) * 1994-10-26 2001-01-11 Novartis Ag Pharmaceutical compositions comprising a macrolide and an acid
IT1289939B1 (en) * 1997-02-20 1998-10-19 Angelini Ricerche Spa AQUEOUS PHARMACEUTICAL COMPOSITION INCLUDING A HIGHLY WATER INSOLUBLE ACTIVE SUBSTANCE
US6063762A (en) * 1997-12-05 2000-05-16 Chong Kun Dang Corp. Cyclosporin-containing microemulsion preconcentrate composition

Also Published As

Publication number Publication date
WO2000032219A1 (en) 2000-06-08
NO20012736D0 (en) 2001-06-01
CA2352388A1 (en) 2000-06-08
AU764413B2 (en) 2003-08-21
PL348062A1 (en) 2002-05-06
NZ512194A (en) 2002-09-27
EP1135152A1 (en) 2001-09-26
NO20012736L (en) 2001-06-01
HUP0105399A2 (en) 2002-06-29
HUP0105399A3 (en) 2005-06-28
AU2016700A (en) 2000-06-19
JP2002531412A (en) 2002-09-24

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