SE9804064D0 - Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells - Google Patents
Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cellsInfo
- Publication number
- SE9804064D0 SE9804064D0 SE9804064A SE9804064A SE9804064D0 SE 9804064 D0 SE9804064 D0 SE 9804064D0 SE 9804064 A SE9804064 A SE 9804064A SE 9804064 A SE9804064 A SE 9804064A SE 9804064 D0 SE9804064 D0 SE 9804064D0
- Authority
- SE
- Sweden
- Prior art keywords
- cells
- growth hormone
- stem cells
- substance
- conditions affecting
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 210000005155 neural progenitor cell Anatomy 0.000 title abstract 3
- 210000001178 neural stem cell Anatomy 0.000 title abstract 3
- 229940126601 medicinal product Drugs 0.000 title abstract 2
- 102000018997 Growth Hormone Human genes 0.000 abstract 5
- 108010051696 Growth Hormone Proteins 0.000 abstract 5
- 210000004027 cell Anatomy 0.000 abstract 5
- 239000000122 growth hormone Substances 0.000 abstract 5
- 210000000130 stem cell Anatomy 0.000 abstract 4
- 239000000126 substance Substances 0.000 abstract 4
- 210000002569 neuron Anatomy 0.000 abstract 3
- 210000004248 oligodendroglia Anatomy 0.000 abstract 3
- 230000001939 inductive effect Effects 0.000 abstract 2
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 210000001130 astrocyte Anatomy 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 210000003061 neural cell Anatomy 0.000 abstract 1
- 230000001902 propagating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/305—Growth hormone [GH], aka. somatotropin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9804064A SE9804064D0 (sv) | 1998-11-25 | 1998-11-25 | Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells |
IL14328399A IL143283A0 (en) | 1998-11-25 | 1999-11-25 | Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells |
PCT/SE1999/002197 WO2000030675A2 (en) | 1998-11-25 | 1999-11-25 | Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells |
CN99815708A CN1333691A (zh) | 1998-11-25 | 1999-11-25 | 用于治疗影响神经干细胞或祖细胞的病症的药用产品及方法 |
AU20138/00A AU772340B2 (en) | 1998-11-25 | 1999-11-25 | Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells |
CA002352553A CA2352553A1 (en) | 1998-11-25 | 1999-11-25 | Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells |
NZ512495A NZ512495A (en) | 1998-11-25 | 1999-11-25 | Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells |
US09/856,576 US6797264B1 (en) | 1998-11-25 | 1999-11-25 | Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells |
EP99963765A EP1135156A2 (en) | 1998-11-25 | 1999-11-25 | Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells |
JP2000583558A JP2002530351A (ja) | 1998-11-25 | 1999-11-25 | 神経幹細胞もしくは始原細胞に影響する症状を処置するための医療製品および方法 |
ZA200104093A ZA200104093B (en) | 1998-11-25 | 2001-05-18 | Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells. |
US10/933,516 US20050032702A1 (en) | 1998-11-25 | 2004-09-03 | Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9804064A SE9804064D0 (sv) | 1998-11-25 | 1998-11-25 | Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9804064D0 true SE9804064D0 (sv) | 1998-11-25 |
Family
ID=20413429
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9804064A SE9804064D0 (sv) | 1998-11-25 | 1998-11-25 | Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells |
Country Status (11)
Country | Link |
---|---|
US (2) | US6797264B1 (zh) |
EP (1) | EP1135156A2 (zh) |
JP (1) | JP2002530351A (zh) |
CN (1) | CN1333691A (zh) |
AU (1) | AU772340B2 (zh) |
CA (1) | CA2352553A1 (zh) |
IL (1) | IL143283A0 (zh) |
NZ (1) | NZ512495A (zh) |
SE (1) | SE9804064D0 (zh) |
WO (1) | WO2000030675A2 (zh) |
ZA (1) | ZA200104093B (zh) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1016413A1 (en) * | 1998-12-30 | 2000-07-05 | Applied Research Systems ARS Holding N.V. | Human growth hormone to stimulate mobilization of pluripotent hematopoietic stem cells |
CA2458261A1 (en) * | 2001-08-30 | 2003-03-06 | Stem Cell Therapeutics Inc. | Differentiation of neural stem cells and therapeutic use thereof |
WO2003024472A2 (en) * | 2001-09-14 | 2003-03-27 | Stem Cell Therapeutics Inc. | Prolactin induced increase in neutral stem cell numbers and therapeutical use thereof |
AU2002325710A1 (en) * | 2001-09-18 | 2003-04-01 | Stem Cell Therapeutics Inc. | Effect of growth hormone and igf-1 on neural stem cells and therapeutic application |
US7368115B2 (en) | 2002-07-31 | 2008-05-06 | Stem Cell Therapeutics Inc. | Method of enhancing neural stem cell proliferation, differentiation, and survival using pituitary adenylate cyclase activating polypeptide (PACAP) |
WO2005077404A1 (en) | 2004-02-13 | 2005-08-25 | Stem Cell Therapeutics Corp. | Use of luteinizing hormone (lh) and chorionic gonadotropin (hcg) for proliferation of neural stem cells and neurogenesis |
CU23529A1 (es) * | 2005-03-02 | 2010-06-17 | Ct Ingenieria Genetica Biotech | Combinación de egf/ghrp-6 para la neuroregeneración del sistema nervioso central posterior al dano autoinmune |
JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス,インコーポレイティド | ムスカリン性受容体調節による神経発生 |
EP2258357A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
CA2664629A1 (en) | 2005-09-27 | 2007-04-05 | Christopher Gregg | Oligodendrocyte precursor cell proliferation regulated by prolactin |
AU2006304787A1 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
US20070112017A1 (en) * | 2005-10-31 | 2007-05-17 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
AU2007223036A1 (en) * | 2006-03-08 | 2007-09-13 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
US8143220B2 (en) * | 2006-03-17 | 2012-03-27 | Stem Cell Therapeutics Corp. | Dosing regimens for neural stem cell proliferating agents and differentiating agents for the treatment of neurological disorders |
EP2026813A2 (en) * | 2006-05-09 | 2009-02-25 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
US20100009983A1 (en) * | 2006-05-09 | 2010-01-14 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
US20090197823A1 (en) | 2006-05-09 | 2009-08-06 | Braincells, Inc. | Aliskiren modulation of neurogenesis |
EP2021000A2 (en) | 2006-05-09 | 2009-02-11 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
JP2010502722A (ja) * | 2006-09-08 | 2010-01-28 | ブレインセルス,インコーポレイティド | 4−アシルアミノピリジン誘導体を含む組み合わせ |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
CA2663347A1 (en) * | 2006-09-19 | 2008-03-27 | Braincells, Inc. | Ppar mediated modulation of neurogenesis |
CU23526B6 (es) | 2006-10-03 | 2010-05-19 | Ct Ingenieria Genetica Biotech | Método para la restauración morfofuncional de nervios periféricos en la neuropatía diabética |
US20080167363A1 (en) * | 2006-12-28 | 2008-07-10 | Braincells, Inc | Modulation of Neurogenesis By Melatoninergic Agents |
US20080171750A1 (en) * | 2007-01-11 | 2008-07-17 | Braincells, Inc. | Modulation Of Neurogenesis With Use of Modafinil |
WO2008097861A2 (en) * | 2007-02-02 | 2008-08-14 | Braincells, Inc. | MODULATION OF NEUROGENESIS WITH BIGUANIDES AND GSK3-ß AGENTS |
US9125891B2 (en) | 2008-03-07 | 2015-09-08 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Lymph nodes as a site for regeneration |
WO2014138486A1 (en) * | 2013-03-06 | 2014-09-12 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Lymph node as a site for transplantation, organogenesis and function for multiple tissues and organs |
WO2009123877A1 (en) * | 2008-03-21 | 2009-10-08 | Braincells, Inc. | A method of treating a nervous system disorder by modulation of neurogenesis with mcc-257 |
US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
US8980338B2 (en) | 2009-03-20 | 2015-03-17 | H.L. Hall & Sons Limited | Sceletium extract and uses thereof |
ES2759675T3 (es) | 2009-03-20 | 2020-05-11 | Hg&H Pharmaceuticals Pty Ltd | Uso de composiciones farmacéuticas que contienen mesembrenona |
US9193710B2 (en) | 2011-08-29 | 2015-11-24 | Sanford-Burnham Medical Research Institute | Benzodiazepinones as modulators of metabotropic glutamate receptor functions and neurological uses thereof |
EP2815769B1 (en) * | 2012-02-15 | 2020-10-21 | Neuracle Science Co., Ltd. | Fam19a5 for use in diagnosing and treatment of cns damages |
JP7044554B2 (ja) | 2015-05-10 | 2022-03-30 | ヴェンタナ メディカル システムズ, インク. | 自動多重組織染色アッセイの間のアルカリホスファターゼ及びペルオキシダーゼ酵素の同時不活化のための組成物と方法 |
AU2018307730B9 (en) | 2017-07-26 | 2024-02-15 | Hg&H Pharmaceuticals (Pty) Ltd | Mesembrenol and/or mesembranol for prophylaxis and treatment of patients suffering from epilepsy and associated diseases |
CN108904779B (zh) * | 2018-09-29 | 2019-12-03 | 南华大学 | 曲普瑞林的新应用 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8625941D0 (en) * | 1986-10-30 | 1986-12-03 | Sandoz Ltd | Substituted alpha-amino acids |
US4871717A (en) * | 1987-01-07 | 1989-10-03 | Administrators Of The Tulane Educational Fund | Peptides |
ATE157546T1 (de) | 1988-01-11 | 1997-09-15 | Chaovanee Aroonsakul | Verwendung von anabolika zur herstellung eines arzneimittels zur behandlung von seniler dementia und der alzheimerschen krankheit |
US5650148A (en) * | 1988-12-15 | 1997-07-22 | The Regents Of The University Of California | Method of grafting genetically modified cells to treat defects, disease or damage of the central nervous system |
CA2053250A1 (en) * | 1989-04-26 | 1990-10-27 | David H. Coy | Linear somatostatin analogs |
AU8864691A (en) * | 1990-09-07 | 1992-03-30 | Regents Of The University Of California, The | Glial antiproliferative proteins |
US5750376A (en) * | 1991-07-08 | 1998-05-12 | Neurospheres Holdings Ltd. | In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny |
US5851832A (en) * | 1991-07-08 | 1998-12-22 | Neurospheres, Ltd. | In vitro growth and proliferation of multipotent neural stem cells and their progeny |
US5980885A (en) * | 1991-07-08 | 1999-11-09 | Neurospheres Holdings Ltd. | Growth factor-induced proliferation of neural precursor cells in vivo |
PT669973E (pt) | 1992-10-28 | 2003-06-30 | Neurospheres Holdings Ltd | Factores biologicos e celulas estaminais neurais |
WO1994022469A1 (en) | 1993-04-02 | 1994-10-13 | Ohio University | Enhancement of learning and/or memory by a human somatotropin |
EP0792350A1 (en) | 1994-11-14 | 1997-09-03 | Neurospheres Holdings Ltd. | Regulation of neural stem cell proliferation |
US6284539B1 (en) * | 1998-10-09 | 2001-09-04 | Neuralstem Biopharmaceuticals, Ltd. | Method for generating dopaminergic cells derived from neural precursors |
-
1998
- 1998-11-25 SE SE9804064A patent/SE9804064D0/xx unknown
-
1999
- 1999-11-25 JP JP2000583558A patent/JP2002530351A/ja active Pending
- 1999-11-25 US US09/856,576 patent/US6797264B1/en not_active Expired - Fee Related
- 1999-11-25 CA CA002352553A patent/CA2352553A1/en not_active Abandoned
- 1999-11-25 NZ NZ512495A patent/NZ512495A/en not_active IP Right Cessation
- 1999-11-25 IL IL14328399A patent/IL143283A0/xx unknown
- 1999-11-25 EP EP99963765A patent/EP1135156A2/en not_active Withdrawn
- 1999-11-25 CN CN99815708A patent/CN1333691A/zh active Pending
- 1999-11-25 AU AU20138/00A patent/AU772340B2/en not_active Ceased
- 1999-11-25 WO PCT/SE1999/002197 patent/WO2000030675A2/en not_active Application Discontinuation
-
2001
- 2001-05-18 ZA ZA200104093A patent/ZA200104093B/en unknown
-
2004
- 2004-09-03 US US10/933,516 patent/US20050032702A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU772340B2 (en) | 2004-04-22 |
WO2000030675A3 (en) | 2000-08-17 |
NZ512495A (en) | 2003-10-31 |
EP1135156A2 (en) | 2001-09-26 |
US20050032702A1 (en) | 2005-02-10 |
CA2352553A1 (en) | 2000-06-02 |
CN1333691A (zh) | 2002-01-30 |
ZA200104093B (en) | 2003-08-18 |
IL143283A0 (en) | 2002-04-21 |
WO2000030675A2 (en) | 2000-06-02 |
US6797264B1 (en) | 2004-09-28 |
AU2013800A (en) | 2000-06-13 |
JP2002530351A (ja) | 2002-09-17 |
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