SE8704093L - THERAPEUTIC AGENTS AND USE THEREOF - Google Patents

THERAPEUTIC AGENTS AND USE THEREOF

Info

Publication number
SE8704093L
SE8704093L SE8704093A SE8704093A SE8704093L SE 8704093 L SE8704093 L SE 8704093L SE 8704093 A SE8704093 A SE 8704093A SE 8704093 A SE8704093 A SE 8704093A SE 8704093 L SE8704093 L SE 8704093L
Authority
SE
Sweden
Prior art keywords
therapeutic agents
isopropylamino
pyrrol
phenoxy
propanol
Prior art date
Application number
SE8704093A
Other languages
Swedish (sv)
Other versions
SE8704093D0 (en
Inventor
F Ostermayer
J Jaekel
N Veillon
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH4235/86A external-priority patent/CH668185A5/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of SE8704093D0 publication Critical patent/SE8704093D0/en
Publication of SE8704093L publication Critical patent/SE8704093L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

(+)-1-Isopropylamino-3-[o-(pyrrol-1-yl)phenoxy]-2-propanol and its salts, its use and preparation and pharmaceutical preparations containing this active substance and their preparation. The use of racemic 1-isopropylamino-3-[o-(pyrrol-1-yl)phenoxy]-2-propanol or a pharmaceutically utilisable, non-toxic salt thereof and pharmaceutical preparations containing an active substance of this type for the treatment of anxiety states are likewise described.
SE8704093A 1986-10-24 1987-10-21 THERAPEUTIC AGENTS AND USE THEREOF SE8704093L (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH4235/86A CH668185A5 (en) 1986-10-24 1986-10-24 Optically active 1-isopropylamino-3-pyrrolyl-phenoxy-2-propanol cpd.
CH17887 1987-01-19
CH92687 1987-03-12
CH92587 1987-03-12

Publications (2)

Publication Number Publication Date
SE8704093D0 SE8704093D0 (en) 1987-10-21
SE8704093L true SE8704093L (en) 1988-04-25

Family

ID=27427782

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8704093A SE8704093L (en) 1986-10-24 1987-10-21 THERAPEUTIC AGENTS AND USE THEREOF

Country Status (16)

Country Link
EP (1) EP0265388A1 (en)
KR (1) KR880005094A (en)
AT (1) ATA281087A (en)
BE (1) BE1002060A3 (en)
DE (1) DE3735641A1 (en)
DK (1) DK554887A (en)
FI (1) FI874643A (en)
FR (1) FR2605629A1 (en)
GB (1) GB2197315A (en)
GR (1) GR871634B (en)
HU (1) HUT45492A (en)
IE (1) IE872860L (en)
NL (1) NL8702533A (en)
NO (1) NO874425L (en)
PT (1) PT85976B (en)
SE (1) SE8704093L (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0265388A1 (en) * 1986-10-24 1988-04-27 Ciba-Geigy Ag Pyrrole derivatives, therapeutic compositions containing them and their use
JPH02131465A (en) * 1988-07-18 1990-05-21 Nippon Tokushu Noyaku Seizo Kk 1-phenylpyrroles and utilization as herbicide

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204241A1 (en) * 1973-03-09 1975-12-10 Ciba Geigy Ag PROCEDURE FOR PREPARING COMPOUNDS DERIVED FROM 1-PYRROLYL (1) -PHENOXY-2-HYDROXY-3-ALKYLAMINE-PROPANE AND 1-PYRROLYL- (1) -PHENOXY-3-HYDROXY-3-MORPHOLINE-PROPANE
DE2835438A1 (en) * 1978-08-12 1980-03-06 Basf Ag AMINOPROPANOL DERIVATIVES OF 2- (O-HYDROXYPHENYL) PYRROL
EP0152379A3 (en) * 1984-02-15 1986-10-29 Ciba-Geigy Ag Process for preparing pharmaceutical compositions containing unilamellar liposomes
EP0265388A1 (en) * 1986-10-24 1988-04-27 Ciba-Geigy Ag Pyrrole derivatives, therapeutic compositions containing them and their use

Also Published As

Publication number Publication date
GR871634B (en) 1988-02-24
NL8702533A (en) 1988-05-16
PT85976B (en) 1990-01-19
IE872860L (en) 1988-04-24
DK554887D0 (en) 1987-10-23
SE8704093D0 (en) 1987-10-21
GB2197315A (en) 1988-05-18
EP0265388A1 (en) 1988-04-27
DE3735641A1 (en) 1988-04-28
FI874643A (en) 1988-04-25
BE1002060A3 (en) 1990-06-12
HUT45492A (en) 1988-07-28
DK554887A (en) 1988-04-05
NO874425L (en) 1988-04-25
FR2605629A1 (en) 1988-04-29
ATA281087A (en) 1989-01-15
FI874643A0 (en) 1987-10-21
NO874425D0 (en) 1987-10-23
PT85976A (en) 1987-11-01
KR880005094A (en) 1988-06-28

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Legal Events

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Effective date: 19910501