SE8501882L - Pyridinderivat och framstellning derav - Google Patents

Pyridinderivat och framstellning derav

Info

Publication number
SE8501882L
SE8501882L SE8501882A SE8501882A SE8501882L SE 8501882 L SE8501882 L SE 8501882L SE 8501882 A SE8501882 A SE 8501882A SE 8501882 A SE8501882 A SE 8501882A SE 8501882 L SE8501882 L SE 8501882L
Authority
SE
Sweden
Prior art keywords
preparation
pyridine derivatives
vasodilating
formulaand
dihydropyridine
Prior art date
Application number
SE8501882A
Other languages
English (en)
Other versions
SE8501882D0 (sv
SE464028B (sv
Inventor
K Kimura
I Morita
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of SE8501882D0 publication Critical patent/SE8501882D0/sv
Publication of SE8501882L publication Critical patent/SE8501882L/sv
Publication of SE464028B publication Critical patent/SE464028B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
    • C07F9/657181—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/6574—Esters of oxyacids of phosphorus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE8501882A 1984-04-19 1985-04-17 1,4-dihydropyridin-3-karboxylat, saett att framstaella denna och en farmaceutisk komposition SE464028B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59079560A JPS60248693A (ja) 1984-04-19 1984-04-19 ピリジン誘導体及び製法

Publications (3)

Publication Number Publication Date
SE8501882D0 SE8501882D0 (sv) 1985-04-17
SE8501882L true SE8501882L (sv) 1985-10-20
SE464028B SE464028B (sv) 1991-02-25

Family

ID=13693390

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8501882A SE464028B (sv) 1984-04-19 1985-04-17 1,4-dihydropyridin-3-karboxylat, saett att framstaella denna och en farmaceutisk komposition

Country Status (15)

Country Link
US (1) US5036059A (sv)
EP (1) EP0159040B1 (sv)
JP (1) JPS60248693A (sv)
KR (1) KR850007603A (sv)
AT (1) ATE83237T1 (sv)
AU (1) AU570552B2 (sv)
BE (1) BE902210A (sv)
DE (1) DE3586879D1 (sv)
ES (1) ES8606276A1 (sv)
FR (1) FR2563222B1 (sv)
GB (1) GB2157695A (sv)
IT (1) IT1209945B (sv)
NL (1) NL8500909A (sv)
SE (1) SE464028B (sv)
ZA (1) ZA852591B (sv)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6163688A (ja) * 1984-08-03 1986-04-01 Nissan Chem Ind Ltd ジヒドロピリジン−５−ホスホン酸環状エステル類
US4885284A (en) * 1986-01-22 1989-12-05 Nissan Chemical Industries Ltd. Dihydropyridine-5-phosphonic acid cyclic propylene ester
CN1016063B (zh) 1986-01-22 1992-04-01 日产化学工业株式会社 二氢吡啶-5-膦酸环亚丙基酯的制备
UA5590A1 (uk) * 1986-01-23 1994-12-28 Ніссан Кемікал Індастріз Лтд Спосіб одержання пропіленглікового ефіру заміщеної 1,4-дігідропіріділ-5-фосфорної кислоти, або його фармацевтично прийнятной солі або сольвата
JPS63115890A (ja) * 1986-10-31 1988-05-20 Nippon Shinyaku Co Ltd ２位置換１，４−ジヒドロピリジン誘導体
JPH01275591A (ja) * 1988-04-27 1989-11-06 Nissan Chem Ind Ltd ジヒドロピリジン−５−ホスホン酸誘導体
EP0353692B1 (en) * 1988-08-02 1995-10-04 Nissan Chemical Industries Ltd. Drug effect-enhancing agent for antitumor drug
JP2850376B2 (ja) * 1988-08-02 1999-01-27 日産化学工業株式会社 抗癌剤薬効増強剤
US20020119201A1 (en) * 2000-09-08 2002-08-29 Novozymes A/S Lubricated granules
US7563782B2 (en) 2003-03-28 2009-07-21 Nissan Chemical Industries, Ltd. T-type calcium channel blocker

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2094678A5 (sv) * 1970-06-30 1972-02-04 Pepro
DE2508181A1 (de) * 1975-02-26 1976-09-09 Bayer Ag 1,4-dihydropyridincarbonsaeurearal- kylester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS59161392A (ja) * 1983-03-04 1984-09-12 Nippon Shinyaku Co Ltd ジヒドロピリジン誘導体及びその製法
EP0141222B1 (en) * 1983-09-26 1989-04-12 Nissan Chemical Industries Ltd. Dihydropyridine-5-phosphonic acid cyclic ester

Also Published As

Publication number Publication date
IT8547862A0 (it) 1985-03-25
SE8501882D0 (sv) 1985-04-17
EP0159040B1 (en) 1992-12-09
FR2563222A1 (fr) 1985-10-25
ES542378A0 (es) 1986-04-01
KR850007603A (ko) 1985-12-07
BE902210A (fr) 1985-10-17
EP0159040A2 (en) 1985-10-23
ES8606276A1 (es) 1986-04-01
ATE83237T1 (de) 1992-12-15
FR2563222B1 (fr) 1989-06-09
EP0159040A3 (en) 1988-08-17
IT1209945B (it) 1989-08-30
JPH0259835B2 (sv) 1990-12-13
AU570552B2 (en) 1988-03-17
US5036059A (en) 1991-07-30
JPS60248693A (ja) 1985-12-09
GB8507897D0 (en) 1985-05-01
NL8500909A (nl) 1985-11-18
SE464028B (sv) 1991-02-25
AU4140585A (en) 1985-10-24
ZA852591B (en) 1986-01-29
DE3586879D1 (de) 1993-01-21
GB2157695A (en) 1985-10-30

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