SE8301785L - SET TO MAKE 2-THIOPHENIC ACETIC ACID DERIVATIVES AND INTERMEDIATES REQUIRED FOR THEIR PREPARATION - Google Patents

SET TO MAKE 2-THIOPHENIC ACETIC ACID DERIVATIVES AND INTERMEDIATES REQUIRED FOR THEIR PREPARATION

Info

Publication number
SE8301785L
SE8301785L SE8301785A SE8301785A SE8301785L SE 8301785 L SE8301785 L SE 8301785L SE 8301785 A SE8301785 A SE 8301785A SE 8301785 A SE8301785 A SE 8301785A SE 8301785 L SE8301785 L SE 8301785L
Authority
SE
Sweden
Prior art keywords
acetic acid
thiophenic
preparation
make
acid derivatives
Prior art date
Application number
SE8301785A
Other languages
Swedish (sv)
Other versions
SE453992B (en
SE8301785D0 (en
Inventor
R Nabet
S Andres
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of SE8301785D0 publication Critical patent/SE8301785D0/en
Publication of SE8301785L publication Critical patent/SE8301785L/en
Publication of SE453992B publication Critical patent/SE453992B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Abstract

A 2-thiophene acetic acid compound of formula (I): <IMAGE> in which: R represents an alkyl radical of 1 to 4 carbon atoms; and R1, R2 and R3 are the same or different and each represents a hydrogen atom, an alkyl radical of 1 to 4 carbon atoms or a halogen atom; is prepared by decarbalkoxylating an alkylmalonate of formula (IV): <IMAGE> in which R, R1, R2 and R3 are as defined above and Alk1 and Alk2 are the same or different and each represents an alkyl radical of 1 to 4 carbon atoms. The 2-thiophene acetic acid compound is an intermediate in the production of pharmaceuticals. The alkylmalonate used is itself claimed per se.
SE8301785A 1982-12-03 1983-03-30 SET TO PREPARE 2-THIOPHENIC ACETIC ACID DERIVATIVES SE453992B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8220271A FR2537137B1 (en) 1982-12-03 1982-12-03 PROCESS FOR THE PREPARATION OF ACETIC 2-THIOPHENE ACID DERIVATIVES AND INTERMEDIATE PRODUCTS NECESSARY FOR THEIR PREPARATION

Publications (3)

Publication Number Publication Date
SE8301785D0 SE8301785D0 (en) 1983-03-30
SE8301785L true SE8301785L (en) 1984-06-04
SE453992B SE453992B (en) 1988-03-21

Family

ID=9279757

Family Applications (2)

Application Number Title Priority Date Filing Date
SE8301785A SE453992B (en) 1982-12-03 1983-03-30 SET TO PREPARE 2-THIOPHENIC ACETIC ACID DERIVATIVES
SE8703494A SE457724B (en) 1982-12-03 1987-09-09 2-TIENYL MALONE DERIVATIVES FOR USE IN THE PREPARATION OF 2-THIOPHENETIC ACID DERIVATIVES

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE8703494A SE457724B (en) 1982-12-03 1987-09-09 2-TIENYL MALONE DERIVATIVES FOR USE IN THE PREPARATION OF 2-THIOPHENETIC ACID DERIVATIVES

Country Status (22)

Country Link
JP (1) JPS59106482A (en)
KR (1) KR900005681B1 (en)
AT (1) AT392784B (en)
AU (1) AU556803B2 (en)
BE (1) BE896439A (en)
CA (1) CA1201441A (en)
CH (2) CH655722A5 (en)
DE (1) DE3314029A1 (en)
DK (2) DK160427C (en)
ES (1) ES521230A0 (en)
FI (1) FI83646C (en)
FR (1) FR2537137B1 (en)
GB (1) GB2132607B (en)
HU (1) HU192136B (en)
IE (1) IE55075B1 (en)
IT (1) IT1174757B (en)
LU (1) LU84748A1 (en)
NL (1) NL8301692A (en)
NZ (1) NZ204509A (en)
PT (1) PT76534B (en)
SE (2) SE453992B (en)
ZA (1) ZA832698B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2083961T3 (en) * 1988-04-22 1996-05-01 Byk Gulden Lomberg Chem Fab ACIDOS 3-ANILINO-2-HIDROXICARBONIL-4-TIOFENOACETICOS.
IT1276738B1 (en) * 1995-06-16 1997-11-03 Erregierre Spa PROCESS FOR THE PREPARATION OF DERIVATIVES OF -METHYL-2- THIOPHENEACETIC ACID
DE102004008807A1 (en) 2004-02-20 2005-09-08 Bayer Cropscience Ag pyrazolopyrimidine
CN113896709B (en) * 2021-11-22 2023-02-28 南京一苇医药科技有限公司 Synthetic method of benzothiophene-3-acetic acid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB683337A (en) * 1949-10-01 1952-11-26 Warner Hudnut Inc Improvements in or relating to the preparation of antispasmodic compounds
IE33054B1 (en) * 1968-04-16 1974-03-06 Ici Ltd Heterocyclic compounds
FR2260575A1 (en) * 1974-02-11 1975-09-05 Innothera Lab Sa Cyclohexyl 3-thienyl acetic acid prodn - from methyl 3-thienylacetate through diethyl cyclohexyl 3-thienyl malonate as starting material for basic esters as drugs
GB2003570B (en) * 1977-06-08 1982-01-20 Imi Opella Ltd Stop valve
FR2421897A1 (en) * 1978-04-04 1979-11-02 Labaz Alpha substd. 3-thienyl:acetamide derivs. - useful as hypnotic, anticonvulsant and tranquillising agents

Also Published As

Publication number Publication date
FI83646B (en) 1991-04-30
CH659817A5 (en) 1987-02-27
DK139983D0 (en) 1983-03-28
FI831115A0 (en) 1983-03-31
IT8348215A0 (en) 1983-05-04
DK138490D0 (en) 1990-06-06
SE8703494L (en) 1987-09-09
KR840006986A (en) 1984-12-04
IE55075B1 (en) 1990-05-23
IE831075L (en) 1984-06-03
FR2537137B1 (en) 1985-07-19
KR900005681B1 (en) 1990-08-06
ES8401957A1 (en) 1984-01-01
DE3314029C2 (en) 1993-03-04
SE453992B (en) 1988-03-21
GB2132607B (en) 1986-05-08
NZ204509A (en) 1986-02-21
SE457724B (en) 1989-01-23
DK160427C (en) 1991-08-19
CA1201441A (en) 1986-03-04
SE8703494D0 (en) 1987-09-09
FI83646C (en) 1991-08-12
HU192136B (en) 1987-05-28
PT76534B (en) 1986-03-12
BE896439A (en) 1983-10-12
ATA286683A (en) 1990-11-15
JPS59106482A (en) 1984-06-20
LU84748A1 (en) 1983-12-05
GB8312701D0 (en) 1983-06-15
PT76534A (en) 1983-05-01
DK164550C (en) 1992-11-30
DE3314029A1 (en) 1984-06-07
GB2132607A (en) 1984-07-11
SE8301785D0 (en) 1983-03-30
DK164550B (en) 1992-07-13
CH655722A5 (en) 1986-05-15
ES521230A0 (en) 1984-01-01
FI831115L (en) 1984-06-04
NL8301692A (en) 1984-07-02
DK139983A (en) 1984-06-04
ZA832698B (en) 1984-05-30
IT1174757B (en) 1987-07-01
AU556803B2 (en) 1986-11-20
AU1357483A (en) 1984-06-07
AT392784B (en) 1991-06-10
DK138490A (en) 1990-06-06
FR2537137A1 (en) 1984-06-08
DK160427B (en) 1991-03-11
JPH0480910B2 (en) 1992-12-21

Similar Documents

Publication Publication Date Title
ES473074A1 (en) Thienothiazine derivatives, their preparation and compositions containing them.
IL68075A0 (en) Pyridine and pyrane derivatives,their preparation and pharmaceutical compositions containing them
ES8605506A1 (en) Piperidine derivatives, their preparation and their therapeutical application.
ES486824A1 (en) Neuroleptic-4-(naphthylmethyl)piperidine derivatives
ES8207180A1 (en) Thienopyridinone derivatives, process for their preparation and their therapeutical use.
SE7703000L (en) PROCEDURE FOR THE PREPARATION OF CARBOSTYRIL DERIVATIVES
YU91483A (en) Process for obtaining new thiomethylpyridine derivatives
SE8301785L (en) SET TO MAKE 2-THIOPHENIC ACETIC ACID DERIVATIVES AND INTERMEDIATES REQUIRED FOR THEIR PREPARATION
ES8202818A1 (en) Tetrazolylcoumarin derivatives, process for preparing the same and composition containing the same.
DK154891C (en) METHOD OF ANALOGY FOR THE PREPARATION OF THIENO-THIAZOLD DERIVATIVES AND THEIR PHYSIOLOGICALLY ACCEPTABLE ACID ADDITION SALTS.
GB2017087A (en) Process for the preparation of xanthone derivatives
ES8400743A1 (en) 1-Phenylindazol-3-one compounds, process and intermediates for their preparation and medicines containing these compounds.
SE8005493L (en) 4- (HAFTALENYLOXI) PIPERIDINE DERIVATIVES
JPS5573677A (en) Thienylbenzoic acid derivative and its production
SE7909157L (en) PROCEDURE FOR THE PREPARATION OF CYCLE-1,3,2-OXAZAPHOSPHORPHYL DERIVATIVES
AU551901B2 (en) Substituted thienobenzodiazepinones
SE7706693L (en) METHODS OF PRODUCING HYDRAZINOPYRIDAZINE DERIVATIVES
SE8207294D0 (en) 1,4-THIAZANCARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE AND COMPOSITIONS OF THESE DERIVATIVES
ES451375A1 (en) 2,4-diamino-5-benzylpyrimidines
GB2017080A (en) Benzothiazepines
JPS57156440A (en) Novel derivatives of 4-methyl-3-formylpentanoic acid, manufacture and use for manufacturing cyclic derivatives
DK452984D0 (en) PROCEDURE FOR PREPARING QUINOLIN-4-ONER
SE8301786L (en) SET TO PREPARE 2-THIOPHENIC ACETIC ACID DERIVATIVES
NO791949L (en) CARBAZOLE DERIVATIVES.
EG16489A (en) Process for the preparation of accridanone derivatives

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8301785-5

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8301785-5

Format of ref document f/p: F