SE8207474L - NEW HETEROCYCLIC CARBOXYLIC ACIDS AND A PROCEDURE FOR PREPARING THEREOF - Google Patents
NEW HETEROCYCLIC CARBOXYLIC ACIDS AND A PROCEDURE FOR PREPARING THEREOFInfo
- Publication number
- SE8207474L SE8207474L SE8207474A SE8207474A SE8207474L SE 8207474 L SE8207474 L SE 8207474L SE 8207474 A SE8207474 A SE 8207474A SE 8207474 A SE8207474 A SE 8207474A SE 8207474 L SE8207474 L SE 8207474L
- Authority
- SE
- Sweden
- Prior art keywords
- general formula
- image
- carboxylic acids
- defined above
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D411/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
New heterocyclic carboxylic acids of the general formula (I), <IMAGE> wherein Y<1> and Y<2> form together a removable carbonyl protecting group and R is a removable amido protecting group, are prepared in such a way that a compound of the general formula (IV), <IMAGE> wherein Z is a C1-5 alkyl group and R is as defined above, is reacted with a compound capable for the temporary protection of the carbonyl group, the resulting compound of the general formula (III), <IMAGE> wherein R, Z, Y<1> and Y<2> are as defined above, is treated with an alkali metal halide, and the resulting compound of the general formula (II), <IMAGE> wherein Z, R, Y<1> and Y<2> are as defined above, is either hydrolysed selectively or separated into its isomers and the trans isomer is then hydrolysed. The resulting compounds of the general formula (I) are valuable intermediates of the synthesis of thienamycin and thienamycin analogues.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU814011A HU184494B (en) | 1981-12-30 | 1981-12-30 | Process for producing new azetidinone-caraoxylic acids |
Publications (3)
Publication Number | Publication Date |
---|---|
SE8207474D0 SE8207474D0 (en) | 1982-12-29 |
SE8207474L true SE8207474L (en) | 1983-07-01 |
SE453082B SE453082B (en) | 1988-01-11 |
Family
ID=10966500
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8207474A SE453082B (en) | 1981-12-30 | 1982-12-29 | AZETIDINON CARBOXYLIC ACIDS AND PROCEDURES FOR PREPARING THEREOF |
Country Status (19)
Country | Link |
---|---|
JP (1) | JPS58118565A (en) |
AT (1) | AT378769B (en) |
AU (1) | AU556905B2 (en) |
BE (1) | BE895493A (en) |
CA (1) | CA1189864A (en) |
CH (1) | CH655927A5 (en) |
DE (1) | DE3248671A1 (en) |
ES (1) | ES518719A0 (en) |
FI (1) | FI824515L (en) |
FR (1) | FR2518997B1 (en) |
GB (1) | GB2112392B (en) |
GR (1) | GR78430B (en) |
HU (1) | HU184494B (en) |
IT (1) | IT1210967B (en) |
LU (1) | LU84566A1 (en) |
NL (1) | NL8205069A (en) |
PL (1) | PL137738B1 (en) |
SE (1) | SE453082B (en) |
ZA (1) | ZA829592B (en) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS55111463A (en) * | 1979-02-21 | 1980-08-28 | Sankyo Co Ltd | Beta-lactam compound and its preparation |
EP0018594B1 (en) * | 1979-04-27 | 1985-08-21 | Merck & Co. Inc. | Process for the preparation of 3-(1-hydroxyethyl)-azetidinones |
JPS56142259A (en) * | 1980-03-11 | 1981-11-06 | Sankyo Co Ltd | Beta-lactam compound and its preparation |
-
1981
- 1981-12-30 HU HU814011A patent/HU184494B/en not_active IP Right Cessation
-
1982
- 1982-12-10 AT AT0450682A patent/AT378769B/en not_active IP Right Cessation
- 1982-12-24 JP JP57235005A patent/JPS58118565A/en active Pending
- 1982-12-28 BE BE1/10680A patent/BE895493A/en not_active IP Right Cessation
- 1982-12-29 LU LU84566A patent/LU84566A1/en unknown
- 1982-12-29 CH CH7603/82A patent/CH655927A5/en not_active IP Right Cessation
- 1982-12-29 FR FR8221977A patent/FR2518997B1/en not_active Expired
- 1982-12-29 SE SE8207474A patent/SE453082B/en not_active IP Right Cessation
- 1982-12-30 AU AU91967/82A patent/AU556905B2/en not_active Ceased
- 1982-12-30 NL NL8205069A patent/NL8205069A/en not_active Application Discontinuation
- 1982-12-30 DE DE19823248671 patent/DE3248671A1/en not_active Withdrawn
- 1982-12-30 IT IT8225059A patent/IT1210967B/en active
- 1982-12-30 CA CA000418738A patent/CA1189864A/en not_active Expired
- 1982-12-30 PL PL1982239884A patent/PL137738B1/en unknown
- 1982-12-30 GB GB08236916A patent/GB2112392B/en not_active Expired
- 1982-12-30 GR GR70185A patent/GR78430B/el unknown
- 1982-12-30 ZA ZA829592A patent/ZA829592B/en unknown
- 1982-12-30 ES ES518719A patent/ES518719A0/en active Granted
- 1982-12-30 FI FI824515A patent/FI824515L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IT1210967B (en) | 1989-09-29 |
AT378769B (en) | 1985-09-25 |
IT8225059A0 (en) | 1982-12-30 |
JPS58118565A (en) | 1983-07-14 |
NL8205069A (en) | 1983-07-18 |
GR78430B (en) | 1984-09-27 |
PL137738B1 (en) | 1986-07-31 |
FI824515A0 (en) | 1982-12-30 |
FR2518997A1 (en) | 1983-07-01 |
ZA829592B (en) | 1983-10-26 |
PL239884A1 (en) | 1984-01-02 |
AU9196782A (en) | 1983-07-07 |
GB2112392A (en) | 1983-07-20 |
ES8504119A1 (en) | 1985-04-16 |
ATA450682A (en) | 1985-02-15 |
GB2112392B (en) | 1985-08-14 |
ES518719A0 (en) | 1985-04-16 |
FI824515L (en) | 1983-07-01 |
SE8207474D0 (en) | 1982-12-29 |
AU556905B2 (en) | 1986-11-27 |
FR2518997B1 (en) | 1985-09-06 |
HU184494B (en) | 1984-08-28 |
BE895493A (en) | 1983-06-28 |
CA1189864A (en) | 1985-07-02 |
CH655927A5 (en) | 1986-05-30 |
LU84566A1 (en) | 1984-10-22 |
DE3248671A1 (en) | 1983-07-07 |
SE453082B (en) | 1988-01-11 |
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Legal Events
Date | Code | Title | Description |
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NUG | Patent has lapsed |
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