SE8105686L - Nya 17-oxazolin-steroidderivat, sett for framstellning derav och anvendning derav vid framstellning av kortikosteroider - Google Patents
Nya 17-oxazolin-steroidderivat, sett for framstellning derav och anvendning derav vid framstellning av kortikosteroiderInfo
- Publication number
- SE8105686L SE8105686L SE8105686A SE8105686A SE8105686L SE 8105686 L SE8105686 L SE 8105686L SE 8105686 A SE8105686 A SE 8105686A SE 8105686 A SE8105686 A SE 8105686A SE 8105686 L SE8105686 L SE 8105686L
- Authority
- SE
- Sweden
- Prior art keywords
- carbon atoms
- group
- oxazoline
- cortic
- costeroids
- Prior art date
Links
- ALEXXDVDDISNDU-JZYPGELDSA-N cortisol 21-acetate Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)COC(=O)C)(O)[C@@]1(C)C[C@@H]2O ALEXXDVDDISNDU-JZYPGELDSA-N 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000000304 alkynyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 239000004215 Carbon black (E152) Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229930195733 hydrocarbon Chemical group 0.000 abstract 1
- 150000002430 hydrocarbons Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/006—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8023575A FR2493324B1 (sv) | 1980-11-05 | 1980-11-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8105686L true SE8105686L (sv) | 1982-05-06 |
| SE440505B SE440505B (sv) | 1985-08-05 |
Family
ID=9247684
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8105686A SE440505B (sv) | 1980-11-05 | 1981-09-25 | Nya oxazolin-steroid-derivat, sett for framstellning derav och anvendning derav vid framstellning av kortikosteroider |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4401596A (sv) |
| JP (1) | JPS57106700A (sv) |
| AT (1) | AT386602B (sv) |
| CH (1) | CH652726A5 (sv) |
| DE (1) | DE3144009A1 (sv) |
| DK (1) | DK162771C (sv) |
| FI (1) | FI72526C (sv) |
| FR (1) | FR2493324B1 (sv) |
| GB (1) | GB2086907B (sv) |
| HU (1) | HU183666B (sv) |
| IT (1) | IT1171613B (sv) |
| NL (1) | NL8104985A (sv) |
| PT (1) | PT73933B (sv) |
| SE (1) | SE440505B (sv) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0123736A1 (en) * | 1983-04-29 | 1984-11-07 | Gist-Brocades N.V. | New process for the preparation of 21-hydroxy-20-keto-delta 16-steroids and new intermediate compounds formed in this process |
| EP0153001B1 (en) * | 1984-02-03 | 1992-03-11 | The Upjohn Company | Steroids having an enamide or enimide group and their preparation |
| FR2559156B1 (fr) * | 1984-02-03 | 1989-03-24 | Roussel Uclaf | Procede de preparation de derives de la prednisone et produits intermediaires de ce procede |
| US4585590A (en) * | 1984-02-03 | 1986-04-29 | The Upjohn Company | Cyanohydrin process |
| US4548748A (en) * | 1984-02-03 | 1985-10-22 | The Upjohn Company | Cyanohydrin process |
| FR2620708B1 (fr) * | 1984-02-03 | 1994-11-04 | Roussel Uclaf | Nouveaux produits industriels, leur procede de preparation et leur application |
| US4831131A (en) * | 1984-02-03 | 1989-05-16 | The Upjohn Company | 11β,17α-Dihydroxy-17β-cyano-androstanes |
| FR2571727B1 (fr) * | 1984-10-16 | 1987-06-12 | Roussel Uclaf | Nouveaux produits steroides comportant, en position 23, un radical dihydro oxazolyle, leur procede de preparation, leur application a la preparation de produits de la serie des 20 cetopregnanes et intermediaires de cette application |
| JP2812397B2 (ja) * | 1988-04-08 | 1998-10-22 | ヘキスト マリオン ルーセル | ９α−ヒドロキシ−１７−メチレンステロイド，その製造方法及びコルチコステロイドの製造方法 |
| ZA909444B (en) * | 1989-11-27 | 1991-08-28 | Schering Corp | Process for dehydrating corticosteroid intermediates |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3338892A (en) * | 1964-11-24 | 1967-08-29 | Lilly Co Eli | Steroidal carbamic acid-gamma-lactones |
| JPS512460B1 (sv) * | 1967-10-05 | 1976-01-26 | ||
| CH549001A (de) * | 1970-04-17 | 1974-05-15 | Ciba Geigy Ag | Verfahren zur herstellung neuer halogensteroide. |
| US4232013A (en) * | 1977-12-03 | 1980-11-04 | Lark S.P.A. | 16,17-Pyrazolino- and 16,17-isopyrazolino-1,4-pregnadiene derivatives |
| HU178397B (en) * | 1978-04-01 | 1982-04-28 | Gyogyszerkutato Intezet | Process for preparing substituted derivatives of steroid-spiro-oxazolidione derivatives |
-
1980
- 1980-11-05 FR FR8023575A patent/FR2493324B1/fr not_active Expired
-
1981
- 1981-09-25 SE SE8105686A patent/SE440505B/sv not_active IP Right Cessation
- 1981-10-27 IT IT49576/81A patent/IT1171613B/it active
- 1981-11-03 FI FI813459A patent/FI72526C/sv not_active IP Right Cessation
- 1981-11-03 US US06/317,584 patent/US4401596A/en not_active Expired - Fee Related
- 1981-11-04 GB GB8133233A patent/GB2086907B/en not_active Expired
- 1981-11-04 PT PT73933A patent/PT73933B/pt not_active IP Right Cessation
- 1981-11-04 DK DK487081A patent/DK162771C/da not_active IP Right Cessation
- 1981-11-04 NL NL8104985A patent/NL8104985A/nl not_active Application Discontinuation
- 1981-11-05 AT AT0475081A patent/AT386602B/de not_active IP Right Cessation
- 1981-11-05 HU HU813304A patent/HU183666B/hu not_active IP Right Cessation
- 1981-11-05 JP JP56176594A patent/JPS57106700A/ja active Granted
- 1981-11-05 DE DE19813144009 patent/DE3144009A1/de not_active Withdrawn
- 1981-11-05 CH CH7092/81A patent/CH652726A5/fr not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IT8149576A0 (it) | 1981-10-27 |
| FI813459L (fi) | 1982-05-06 |
| FR2493324B1 (sv) | 1983-01-21 |
| DK487081A (da) | 1982-05-06 |
| NL8104985A (nl) | 1982-06-01 |
| JPS57106700A (en) | 1982-07-02 |
| FR2493324A1 (sv) | 1982-05-07 |
| DK162771C (da) | 1992-04-27 |
| AT386602B (de) | 1988-09-26 |
| PT73933B (fr) | 1983-11-30 |
| IT1171613B (it) | 1987-06-10 |
| CH652726A5 (fr) | 1985-11-29 |
| FI72526B (fi) | 1987-02-27 |
| PT73933A (fr) | 1981-12-01 |
| GB2086907B (en) | 1984-12-12 |
| SE440505B (sv) | 1985-08-05 |
| DK162771B (da) | 1991-12-09 |
| US4401596A (en) | 1983-08-30 |
| FI72526C (sv) | 1987-06-08 |
| GB2086907A (en) | 1982-05-19 |
| ATA475081A (de) | 1988-02-15 |
| HU183666B (en) | 1984-05-28 |
| DE3144009A1 (de) | 1982-06-16 |
| JPH026359B2 (sv) | 1990-02-08 |
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| NAL | Patent in force |
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| NUG | Patent has lapsed |
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