SE8007133L - BENSO (IJ) QUINOLIZIN-2-CARBOXYLIC ACID DERIVATIVES, THERAPEUTIC COMPOSITION CONTAINING THIS SUBSTANCE AND PREPARATION OF THEM - Google Patents
BENSO (IJ) QUINOLIZIN-2-CARBOXYLIC ACID DERIVATIVES, THERAPEUTIC COMPOSITION CONTAINING THIS SUBSTANCE AND PREPARATION OF THEMInfo
- Publication number
- SE8007133L SE8007133L SE8007133A SE8007133A SE8007133L SE 8007133 L SE8007133 L SE 8007133L SE 8007133 A SE8007133 A SE 8007133A SE 8007133 A SE8007133 A SE 8007133A SE 8007133 L SE8007133 L SE 8007133L
- Authority
- SE
- Sweden
- Prior art keywords
- group substituted
- group
- benso
- quinolizin
- substance
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Benzo[ij]quinolizine-2-carboxylic acids of the formula:- <IMAGE> wherein R<1> represents a hydrogen atom or a lower alkyl group; R<2> represents a hydrogen atom or a halogen atom; R<3> represents a lower alkyl group substituted with one or more of a halogen atom and a hydroxy group, a lower alkanoyl group substituted with one or more halogen atoms, a phenylalkyl group substituted with one or more lower alkoxy groups on the phenyl ring, a lower alkanesulfonyl group substituted with one or more halogen atoms, a lower alkenyl group or a lower alkynyl group; or pharmaceutically acceptable salts thereof, have antimicrobial activity. They are particularly effective on those bacteria resistant to conventional antibiotics and can be maintained at high concentration levels in blood for extended periods of time.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP54131630A JPS6019910B2 (en) | 1979-10-11 | 1979-10-11 | Benzo[ij]quinolidine-2-carboxylic acid derivative and method for producing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8007133L true SE8007133L (en) | 1981-04-12 |
SE445917B SE445917B (en) | 1986-07-28 |
Family
ID=15062532
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8007133A SE445917B (en) | 1979-10-11 | 1980-10-10 | BENSO (IJ) QUINOLIZIN-2-CARBOXYLIC ACID DERIVATIVES, PREPARING THEREOF AND THERAPEUTIC COMPOSITION |
Country Status (12)
Country | Link |
---|---|
JP (1) | JPS6019910B2 (en) |
AU (1) | AU536230B2 (en) |
BE (1) | BE885605A (en) |
CA (1) | CA1156232A (en) |
CH (1) | CH644859A5 (en) |
DE (1) | DE3037103A1 (en) |
ES (1) | ES496312A0 (en) |
FR (1) | FR2467205A1 (en) |
GB (1) | GB2062627B (en) |
IT (1) | IT1143997B (en) |
NL (1) | NL187020C (en) |
SE (1) | SE445917B (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO156828C (en) * | 1980-11-10 | 1987-12-02 | Otsuka Pharma Co Ltd | ANALOGY PROCEDURE FOR THE PREPARATION OF ANTIBACTERYLY EFFECTIVE BENZOHETEROCYCLIC COMPOUNDS. |
JPS57176987A (en) * | 1981-04-24 | 1982-10-30 | Otsuka Pharmaceut Co Ltd | Pyrrolo(3,2,1-ij)quinoline-5-carboxylic acid derivative |
US4400386A (en) * | 1981-11-06 | 1983-08-23 | Riker Laboratories, Inc. | Antimicrobial derivatives of 8-amino and 8-aminomethyl benzo(ij)quinolizine |
US4472406A (en) * | 1982-11-12 | 1984-09-18 | Riker Laboratories, Inc. | Antimicrobial 6,7-dihydro-8-(imidazol-1-yl)-5-methyl-1-oxo-1H,5H-benzo [ij]quinolizine-2-carboxylic acids and derivatives |
JPS59137482A (en) * | 1983-01-26 | 1984-08-07 | Otsuka Pharmaceut Co Ltd | Pyrrolo(3,2,1,-ij)quinoline-5-carboxylic acid derivative |
JPS59155381A (en) * | 1983-02-22 | 1984-09-04 | Kyorin Pharmaceut Co Ltd | Benzoquinolizinecarboxylic acid derivative and its preparation |
DE3333719A1 (en) * | 1983-09-17 | 1985-04-04 | Bayer Ag | SOLUTIONS MILK ACID SALTS OF PIPERAZINYL CHINOLONIC AND PIPERAZINYL AZACHINOLONE CARBONIC ACIDS |
JPS60161987A (en) * | 1984-01-31 | 1985-08-23 | Otsuka Pharmaceut Co Ltd | Benzoheterocyclic ring derivative |
DE3517709A1 (en) * | 1985-01-05 | 1986-07-10 | Bayer Ag | BASIC PREPARATIONS OF CHINOLON CARBON ACIDS |
AU585981B2 (en) * | 1985-05-24 | 1989-06-29 | Tokyo Tanabe Company Limited | Benzo (IJ) quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and processes for preparing the same |
DE3741026A1 (en) * | 1987-12-03 | 1989-06-15 | Muetek Laser Und Opto Elektron | METHOD AND SYSTEM FOR (TRACK) GAS ANALYSIS |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE793524A (en) * | 1971-12-30 | 1973-06-29 | Riker Laboratories Inc | BENZOQUINOLIZINE-CARBOXYLIC ACIDS AND THEIR DERIVATIVES |
JPS6034957B2 (en) * | 1978-04-12 | 1985-08-12 | 大塚製薬株式会社 | penicillanic acid derivatives |
-
1979
- 1979-10-11 JP JP54131630A patent/JPS6019910B2/en not_active Expired
-
1980
- 1980-10-01 DE DE19803037103 patent/DE3037103A1/en active Granted
- 1980-10-06 CH CH743580A patent/CH644859A5/en not_active IP Right Cessation
- 1980-10-09 BE BE0/202389A patent/BE885605A/en not_active IP Right Cessation
- 1980-10-09 CA CA000362012A patent/CA1156232A/en not_active Expired
- 1980-10-09 IT IT49851/80A patent/IT1143997B/en active
- 1980-10-09 AU AU63090/80A patent/AU536230B2/en not_active Ceased
- 1980-10-10 SE SE8007133A patent/SE445917B/en not_active IP Right Cessation
- 1980-10-10 GB GB8032782A patent/GB2062627B/en not_active Expired
- 1980-10-10 FR FR8021722A patent/FR2467205A1/en active Granted
- 1980-10-10 NL NLAANVRAGE8005613,A patent/NL187020C/en not_active IP Right Cessation
- 1980-10-11 ES ES496312A patent/ES496312A0/en active Granted
Also Published As
Publication number | Publication date |
---|---|
BE885605A (en) | 1981-02-02 |
FR2467205B1 (en) | 1983-10-07 |
FR2467205A1 (en) | 1981-04-17 |
CH644859A5 (en) | 1984-08-31 |
DE3037103C2 (en) | 1989-06-15 |
AU6309080A (en) | 1981-04-16 |
NL187020C (en) | 1991-05-01 |
JPS6019910B2 (en) | 1985-05-18 |
GB2062627B (en) | 1983-12-07 |
AU536230B2 (en) | 1984-05-03 |
SE445917B (en) | 1986-07-28 |
CA1156232A (en) | 1983-11-01 |
NL187020B (en) | 1990-12-03 |
JPS5655389A (en) | 1981-05-15 |
IT8049851A0 (en) | 1980-10-09 |
DE3037103A1 (en) | 1981-05-07 |
ES8106903A1 (en) | 1981-10-01 |
ES496312A0 (en) | 1981-10-01 |
GB2062627A (en) | 1981-05-28 |
IT1143997B (en) | 1986-10-29 |
NL8005613A (en) | 1981-04-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
NUG | Patent has lapsed |
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