SE7811322L - NEW DERIVATIVES OF PHTHALAZINE WITH THERAPEUTIC ACTIVITY - Google Patents

NEW DERIVATIVES OF PHTHALAZINE WITH THERAPEUTIC ACTIVITY

Info

Publication number: SE7811322L
Authority: SE; Sweden
Prior art keywords: phthalazine; therapeutic activity; new derivatives; derivatives; new
Prior art date: 1977-11-03

Application number

SE7811322A

Other languages

Swedish (sv)

Inventor

S F Campbell

A L Ham

J C Danilewicz

J K Stubbs

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-11-03

Filing date

1978-11-01

Publication date

1979-05-04

1978-11-01 Application filed by Pfizer filed Critical Pfizer

1979-05-04 Publication of SE7811322L publication Critical patent/SE7811322L/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Cardiology (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)
Hydrogenated Pyridines (AREA)

SE7811322A 1977-11-03 1978-11-01 NEW DERIVATIVES OF PHTHALAZINE WITH THERAPEUTIC ACTIVITY SE7811322L (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB4567077		1977-11-03

Publications (1)

Publication Number	Publication Date
SE7811322L true SE7811322L (en)	1979-05-04

Family

ID=10438118

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7811322A SE7811322L (en)	1977-11-03	1978-11-01	NEW DERIVATIVES OF PHTHALAZINE WITH THERAPEUTIC ACTIVITY

Country Status (20)

Country	Link
JP (1)	JPS5498783A (en)
AR (3)	AR219561A1 (en)
AT (1)	AT365184B (en)
AU (1)	AU507007B2 (en)
BE (1)	BE871770A (en)
CA (1)	CA1114379A (en)
DE (1)	DE2847621A1 (en)
DK (1)	DK487978A (en)
ES (5)	ES474764A0 (en)
FI (1)	FI783326A (en)
FR (1)	FR2407927A1 (en)
IE (1)	IE47481B1 (en)
IL (1)	IL55844A (en)
IT (1)	IT1101279B (en)
LU (1)	LU80458A1 (en)
NL (1)	NL7810864A (en)
PH (1)	PH14659A (en)
PT (1)	PT68734A (en)
SE (1)	SE7811322L (en)
YU (3)	YU253678A (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6215356U (en) *	1985-07-15	1987-01-29
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
US20060211707A1 (en) *	2003-05-07	2006-09-21	Hamed Aissaoui	Piperazine-alkyl-ureido derivatives
AU2006311577B2 (en)	2005-11-09	2013-02-07	Zalicus Inc.	Methods, compositions, and kits for the treatment of medical conditions
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
AU2008261102B2 (en)	2007-06-04	2013-11-28	Bausch Health Ireland Limited	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2328910B1 (en)	2008-06-04	2014-08-06	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP3241839B1 (en)	2008-07-16	2019-09-04	Bausch Health Ireland Limited	Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
MX357121B (en)	2011-03-01	2018-06-27	Synergy Pharmaceuticals Inc Star	Process of preparing guanylate cyclase c agonists.
EP2804603A1 (en)	2012-01-10	2014-11-26	President and Fellows of Harvard College	Beta-cell replication promoting compounds and methods of their use
EP2958577A2 (en)	2013-02-25	2015-12-30	Synergy Pharmaceuticals Inc.	Guanylate cyclase receptor agonists for use in colonic cleansing
WO2014151206A1 (en)	2013-03-15	2014-09-25	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase and their uses
AU2014235209B2 (en)	2013-03-15	2018-06-14	Bausch Health Ireland Limited	Guanylate cyclase receptor agonists combined with other drugs
BR112015030326A2 (en)	2013-06-05	2017-08-29	Synergy Pharmaceuticals Inc	ULTRAPURE GUANYLATE CYCLASE C AGONISTS, METHOD OF MANUFACTURING AND USING THEM
US20160184387A1 (en)	2013-08-09	2016-06-30	Dominique Charmot	Compounds and methods for inhibiting phosphate transport
WO2020237096A1 (en)	2019-05-21	2020-11-26	Ardelyx, Inc.	Combination for lowering serum phosphate in a patient

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1293565A (en) *	1969-05-03	1972-10-18	Aspro Nicholas Ltd	Aminophthalazines and pharmaceutical compositions thereof

1978
- 1978-10-24 CA CA314,085A patent/CA1114379A/en not_active Expired
- 1978-10-30 PH PH21752A patent/PH14659A/en unknown
- 1978-10-31 LU LU80458A patent/LU80458A1/en unknown
- 1978-11-01 SE SE7811322A patent/SE7811322L/en unknown
- 1978-11-01 FI FI783326A patent/FI783326A/en unknown
- 1978-11-01 IL IL55844A patent/IL55844A/en unknown
- 1978-11-01 NL NL7810864A patent/NL7810864A/en not_active Application Discontinuation
- 1978-11-01 DK DK487978A patent/DK487978A/en unknown
- 1978-11-01 YU YU02536/78A patent/YU253678A/en unknown
- 1978-11-02 JP JP13569778A patent/JPS5498783A/en active Granted
- 1978-11-02 AU AU41276/78A patent/AU507007B2/en not_active Expired
- 1978-11-02 IT IT29369/78A patent/IT1101279B/en active
- 1978-11-02 DE DE19782847621 patent/DE2847621A1/en not_active Ceased
- 1978-11-02 FR FR7831063A patent/FR2407927A1/en active Granted
- 1978-11-02 IE IE2166/78A patent/IE47481B1/en unknown
- 1978-11-02 AT AT0783978A patent/AT365184B/en not_active IP Right Cessation
- 1978-11-02 PT PT68734A patent/PT68734A/en unknown
- 1978-11-02 ES ES474764A patent/ES474764A0/en active Pending
- 1978-11-03 BE BE191543A patent/BE871770A/en unknown
- 1978-11-10 AR AR274311A patent/AR219561A1/en active
1979
- 1979-04-26 ES ES479994A patent/ES479994A1/en not_active Expired
- 1979-04-26 ES ES479993A patent/ES479993A1/en not_active Expired
- 1979-04-26 ES ES479992A patent/ES479992A1/en not_active Expired
- 1979-04-26 ES ES479991A patent/ES479991A1/en not_active Expired
- 1979-11-02 AR AR278749A patent/AR217577A1/en active
- 1979-11-02 AR AR278750A patent/AR217578A1/en active
1982
- 1982-03-23 YU YU02115/82A patent/YU211582A/en unknown
- 1982-09-23 YU YU02116/82A patent/YU211682A/en unknown

Also Published As

Publication number	Publication date
ES474764A0 (en)	1980-08-16
IL55844A (en)	1982-05-31
PT68734A (en)	1978-12-01
AU4127678A (en)	1979-05-17
IT7829369A0 (en)	1978-11-02
ES479994A1 (en)	1980-08-16
FI783326A (en)	1979-05-04
AT365184B (en)	1981-12-28
FR2407927A1 (en)	1979-06-01
IL55844A0 (en)	1979-01-31
AR217577A1 (en)	1980-03-31
IE47481B1 (en)	1984-04-04
ES479992A1 (en)	1980-09-01
ES479991A1 (en)	1980-08-16
JPS5498783A (en)	1979-08-03
AR217578A1 (en)	1980-03-31
BE871770A (en)	1979-05-03
IT1101279B (en)	1985-09-28
DE2847621A1 (en)	1979-05-17
YU253678A (en)	1983-02-28
AU507007B2 (en)	1980-01-31
CA1114379A (en)	1981-12-15
YU211582A (en)	1983-02-28
PH14659A (en)	1981-10-20
NL7810864A (en)	1979-05-07
LU80458A1 (en)	1980-05-07
IE782166L (en)	1979-05-03
JPS5538352B2 (en)	1980-10-03
YU211682A (en)	1983-02-28
DK487978A (en)	1979-05-04
AR219561A1 (en)	1980-08-29
ES479993A1 (en)	1980-08-16
FR2407927B1 (en)	1982-07-16
ATA783978A (en)	1981-05-15

Publication	Publication Date	Title
NO148148C (en)	1983-08-17	PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 4-HYDROXY-2-PYRROLIDINON DERIVATIVES
FI781753A (en)	1978-12-04	NYA PHTHALAZINE DERIVATIVES
SE7811322L (en)	1979-05-04	NEW DERIVATIVES OF PHTHALAZINE WITH THERAPEUTIC ACTIVITY
SE7811323L (en)	1979-05-04	NEW CHINAZOLINE DERIVATIVES WITH THERAPEUTIC ACTIVITY
SE7812268L (en)	1979-05-31	PHENYLGLYCINE DERIVATIVES WITH THERAPEUTIC EFFECT
NO150482C (en)	1984-10-24	INTERMEDIATES FOR THE PREPARATION OF THERAPEUTIC ACTIVE ANTHRAKINON DERIVATIVES
SE423544B (en)	1982-05-10	ANALOGY PROCEDURE FOR THE PREPARATION OF IMIDAZOLD DERIVATIVES WITH ANTIFUNGIC ACTIVITY
SE429338B (en)	1983-08-29	PROCEDURE FOR THE PREPARATION OF SUBSTITUTED 2-BENZYLPYRROLIDINES WITH THERAPEUTIC EFFECT
SE7802603L (en)	1978-09-09	PROCEDURE FOR PRODUCTION OF THERAPEUTIC AGENTS
SE7804736L (en)	1978-10-27	PROCEDURE FOR THE PREPARATION OF ISOINDOLIN DERIVATIVES WITH THERAPEUTIC EFFECT
SE7800930L (en)	1978-08-04	PROCEDURE FOR THE PREPARATION OF BENZENESULPHONAMIDE AND BENSENCARBOXAMIDE DERIVATIVES WITH THERAPEUTIC EFFECT
SE7800681L (en)	1978-07-21	PROCEDURE FOR THE PREPARATION OF NEW ISOKINOLIN DERIVATIVES
NO780644L (en)	1978-08-25	PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 9-HYDROXYETHOXYMETHYLGUANINE DERIVATIVES
SE421917B (en)	1982-02-08	ANALOGY PROCEDURE FOR PREPARING NEW DERIVATIVES OF 2-METHYL-1-INDOLYL-ETHIC ACID WITH THERAPEUTIC EFFECT
SE7811770L (en)	1979-05-17	NEW DERIVATIVES OF 4-AMINO-2-PIPERIDINO-KINAZOLINE WITH THERAPEUTIC PROPERTIES
FI780350A (en)	1978-08-10	NYA THERAPEUTIC MEDAL
NO145656C (en)	1982-05-05	ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 1-PHENYLETANOLAMINE DERIVATIVES
NO146744C (en)	1982-12-01	ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY (OMEGA-AMINOALCOXY) -DIBENZYL DERIVATIVES
SE7805105L (en)	1978-11-05	PROCEDURE FOR THE PREPARATION OF PYRANOKINOLINE DERIVATIVES WITH THERAPEUTIC EFFECT
SE7805588L (en)	1978-11-18	PROCEDURE FOR THE PREPARATION OF NEW 4-HYDROXITIAZOLIDIN-2-THION DERIVATIVES
SE7811595L (en)	1979-05-11	NEW DERIVATIVES OF ISOKINOLIN
NO151363C (en)	1985-03-27	ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY 16-METOXY-16-METHYL-PROSTAGLANDIN E1 DERIVATIVES
NO146500C (en)	1982-10-13	ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY 4-N-SUBSTITUTED DERIVATIVES OF FORTIMICIN-B
SE7701551L (en)	1977-08-28	PROCEDURE FOR PREPARATION OF BENZENE CARBOXAMIDE DERIVATIVES WITH THERAPEUTIC EFFECT
SE399555B (en)	1978-02-20	INTERMEDIATES FOR THE PREPARATION OF 4-AMINOAMPHETAMINE DERIVATIVES WITH THERAPEUTIC ACTIVITY