SE7810895L - Framstellning av 6,11-dihydro-11-oxodibens(b,e)-oxepin-2-ettiksyra och mellanprodukter herfor - Google Patents

Framstellning av 6,11-dihydro-11-oxodibens(b,e)-oxepin-2-ettiksyra och mellanprodukter herfor

Info

Publication number
SE7810895L
SE7810895L SE7810895A SE7810895A SE7810895L SE 7810895 L SE7810895 L SE 7810895L SE 7810895 A SE7810895 A SE 7810895A SE 7810895 A SE7810895 A SE 7810895A SE 7810895 L SE7810895 L SE 7810895L
Authority
SE
Sweden
Prior art keywords
oxodibens
oxepin
dihydro
preparation
intermediate products
Prior art date
Application number
SE7810895A
Other languages
English (en)
Inventor
A R Mcfadden
R C Allen
T B K Lee
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of SE7810895L publication Critical patent/SE7810895L/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12—[b,e]-condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SE7810895A 1977-10-19 1978-10-19 Framstellning av 6,11-dihydro-11-oxodibens(b,e)-oxepin-2-ettiksyra och mellanprodukter herfor SE7810895L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/843,482 US4118401A (en) 1977-10-19 1977-10-19 Preparation of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid and precursors therefor

Publications (1)

Publication Number Publication Date
SE7810895L true SE7810895L (sv) 1979-04-20

Family

ID=25290114

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7810895A SE7810895L (sv) 1977-10-19 1978-10-19 Framstellning av 6,11-dihydro-11-oxodibens(b,e)-oxepin-2-ettiksyra och mellanprodukter herfor
SE8301997A SE8301997D0 (sv) 1977-10-19 1983-04-11 Framstellning av 6,11-dihydro-11-oxodibens(b,e)-oxepin-2-ettiksyra

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE8301997A SE8301997D0 (sv) 1977-10-19 1983-04-11 Framstellning av 6,11-dihydro-11-oxodibens(b,e)-oxepin-2-ettiksyra

Country Status (9)

Country Link
US (4) US4118401A (sv)
JP (1) JPS5461189A (sv)
AR (2) AR223329A1 (sv)
AT (1) AT369737B (sv)
CA (1) CA1110636A (sv)
ES (2) ES474162A1 (sv)
HU (1) HU180245B (sv)
NL (1) NL7810456A (sv)
SE (2) SE7810895L (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4118401A (en) * 1977-10-19 1978-10-03 American Hoechst Corporation Preparation of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid and precursors therefor
US4515946A (en) * 1981-12-23 1985-05-07 Hoechst-Roussel Pharmaceuticals Inc. 6,11-Dihydro-11-oxo-dibenz-[b,e]oxepin derivatives
US4576960A (en) * 1981-12-23 1986-03-18 Hoechst Roussel Pharmaceuticals Incorporated 6,11-Dihydro-11-oxo-dibenz[b,e]oxepin derivatives
US7687646B2 (en) * 2006-03-28 2010-03-30 Azad Pharmaceutical Ingredients, Ag Polymorphic forms of olopatadine hydrochloride and methods for producing olopatadine and salts thereof
CA2897651C (en) 2013-01-10 2021-09-21 Pulmokine, Inc. Non-selective kinase inhibitors
CN111743901B (zh) 2013-10-11 2023-09-12 普尔莫凯恩股份有限公司 喷雾干燥制剂
CN106518833A (zh) * 2015-09-15 2017-03-22 江苏吉贝尔药业股份有限公司 一种新的6，11-二氢-11-氧代二苯并［b，e］噁庚因-2-乙酸制备方法
WO2018081567A1 (en) 2016-10-27 2018-05-03 Pulmokine, Inc. Combination therapy for treating pulmonary hypertension

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1409411A (fr) * 1964-07-16 1965-08-27 Imprimerie Darboy Perfectionnements apportés aux moyens pour l'élaboration d'emballages transparents étanches et aux emballages correspondants
FR1409441A (fr) * 1964-07-17 1965-08-27 France Ministre Des Armees Perfectionnements au procédé de préparation d'acides para-alkoxy-phénylalkylène-carboxyliques
DE2600768C2 (de) * 1975-02-04 1983-10-27 Hoechst Ag, 6230 Frankfurt Verfahren zur Herstellung von 6,11-Dihydro-11-oxodibenz[b,e]-oxepin-alkansäuren
US4118401A (en) * 1977-10-19 1978-10-03 American Hoechst Corporation Preparation of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid and precursors therefor

Also Published As

Publication number Publication date
SE8301997L (sv) 1983-04-11
ATA747878A (de) 1982-06-15
US4153791A (en) 1979-05-08
AT369737B (de) 1983-01-25
US4160781A (en) 1979-07-10
ES474162A1 (es) 1979-09-01
ES474975A1 (es) 1980-02-16
JPS5461189A (en) 1979-05-17
HU180245B (en) 1983-02-28
US4118401A (en) 1978-10-03
SE8301997D0 (sv) 1983-04-11
NL7810456A (nl) 1979-04-23
CA1110636A (en) 1981-10-13
AR224905A1 (es) 1982-01-29
US4153790A (en) 1979-05-08
AR223329A1 (es) 1981-08-14

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