SE7706520L - Guanidinderivat - Google Patents
GuanidinderivatInfo
- Publication number
- SE7706520L SE7706520L SE7706520A SE7706520A SE7706520L SE 7706520 L SE7706520 L SE 7706520L SE 7706520 A SE7706520 A SE 7706520A SE 7706520 A SE7706520 A SE 7706520A SE 7706520 L SE7706520 L SE 7706520L
- Authority
- SE
- Sweden
- Prior art keywords
- lower alkyl
- represent
- halogen
- trifluoromethyl
- represent hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
- C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB23331/76A GB1530675A (en) | 1976-06-05 | 1976-06-05 | Guanidine derivatives |
GB305677 | 1977-01-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
SE7706520L true SE7706520L (sv) | 1978-01-20 |
SE424861B SE424861B (sv) | 1982-08-16 |
Family
ID=26237989
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7706520A SE424861B (sv) | 1976-06-05 | 1977-06-03 | Forfarande att framstella nya terapeutiskt aktiva derivat av guanidin innehallande en pyrrol-, pyrrolin- eller pyrrolidinrest |
Country Status (15)
Country | Link |
---|---|
US (1) | US4140793A (sv) |
JP (1) | JPS52151161A (sv) |
AU (1) | AU509883B2 (sv) |
CA (1) | CA1070691A (sv) |
CH (1) | CH641159A5 (sv) |
CY (1) | CY1130A (sv) |
DE (1) | DE2724989A1 (sv) |
DK (1) | DK248177A (sv) |
FR (1) | FR2353530A1 (sv) |
HK (1) | HK57981A (sv) |
IE (1) | IE45198B1 (sv) |
KE (1) | KE3170A (sv) |
MY (1) | MY8200180A (sv) |
NL (1) | NL7706173A (sv) |
SE (1) | SE424861B (sv) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1580559A (en) * | 1977-11-24 | 1980-12-03 | Wyeth John & Brother Ltd | Amide cerivatives |
GB1588096A (en) * | 1978-05-20 | 1981-04-15 | Wyeth & Bros Ltd John | Pyrrole derivatives |
US4332822A (en) * | 1980-02-05 | 1982-06-01 | John Wyeth & Brother Limited | Guanidine derivatives |
FR2490026A1 (fr) * | 1980-09-09 | 1982-03-12 | Thomson Csf | Antenne reseau non dispersive et son application a la realisation d'une antenne a balayage electronique |
US4563475A (en) * | 1984-01-13 | 1986-01-07 | William H. Rorer, Inc. | Guanidine derivatives for treating gastrointestinal motility dysfunction |
JPH01106831U (sv) * | 1988-01-08 | 1989-07-19 | ||
JPH0742036Y2 (ja) * | 1988-06-22 | 1995-09-27 | ダイキン工業株式会社 | スポットエアコンのダクト取付構造 |
PE20060459A1 (es) * | 2004-06-16 | 2006-05-30 | Wyeth Corp | DERIVADOS DE AMINO-5,5-DIFENILIMIDAZOLONA COMO INHIBIDORES DE LA ß-SECRETASA |
AU2005264917A1 (en) * | 2004-06-16 | 2006-01-26 | Wyeth | Diphenylimidazopyrimidine and -imidazole amines as inhibitors of B-secretase |
CN101103034A (zh) * | 2005-01-14 | 2008-01-09 | 惠氏公司 | 抑制β-分泌酶的氨基-咪唑酮 |
WO2006083760A1 (en) * | 2005-02-01 | 2006-08-10 | Wyeth | AMINO-PYRIDINES AS INHIBITORS OF β-SECRETASE |
CN101146769A (zh) * | 2005-02-14 | 2008-03-19 | 惠氏公司 | 作为β-分泌酶抑制剂的唑基酰基胍 |
WO2007005404A1 (en) * | 2005-06-30 | 2007-01-11 | Wyeth | AMINO-5-(6-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR ß-SECRETASE MODULATION |
TW200738683A (en) * | 2005-06-30 | 2007-10-16 | Wyeth Corp | Amino-5-(5-membered)heteroarylimidazolone compounds and the use thereof for β-secretase modulation |
TW200730523A (en) * | 2005-07-29 | 2007-08-16 | Wyeth Corp | Cycloalkyl amino-hydantoin compounds and use thereof for β-secretase modulation |
EP2256107A1 (en) * | 2005-09-26 | 2010-12-01 | Wyeth LLC | Amino-5-[4-(difluoromethoxy)phenyl]-5-phenylimidazolone compounds as inhibitors of the beta-secretase (BACE) |
CN101360737A (zh) * | 2005-12-19 | 2009-02-04 | 惠氏公司 | 2-氨基-5-哌啶咪唑酮化合物和其用于β分泌酶调节的用途 |
WO2007100536A1 (en) * | 2006-02-24 | 2007-09-07 | Wyeth | DIHYDROSPIRO[DIBENZO[A,D][7]ANNULENE-5,4'-IMIDAZOL] COMPOUNDS FOR THE INHIBITION OF β-SECRETASE |
US7700606B2 (en) * | 2006-08-17 | 2010-04-20 | Wyeth Llc | Imidazole amines as inhibitors of β-secretase |
JP2010504326A (ja) * | 2006-09-21 | 2010-02-12 | ワイス エルエルシー | β−セクレターゼを阻害するためのインドリルアルキルピリジン−2−アミン |
PE20090160A1 (es) * | 2007-03-20 | 2009-02-11 | Wyeth Corp | COMPUESTOS AMINO-5-[4-(DIFLUOROMETOXI)FENIL SUSTITUIDO]-5-FENILIMIDAZOLONA COMO INHIBIDORES DE ß-SECRETASA |
PE20090617A1 (es) * | 2007-03-23 | 2009-05-08 | Wyeth Corp | Compuestos amino-5-[-4-(difluorometoxi)fenil]-5-fenilimidazolona para la inhibicion de -secretasa |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3189601A (en) * | 1964-01-10 | 1965-06-15 | Ciba Geigy Corp | N, n-alkylene-imino-lower alkanoamidine compounds |
-
1977
- 1977-05-17 IE IE1011/77A patent/IE45198B1/en unknown
- 1977-05-20 AU AU25356/77A patent/AU509883B2/en not_active Expired
- 1977-05-24 CA CA279,260A patent/CA1070691A/en not_active Expired
- 1977-05-31 US US05/801,973 patent/US4140793A/en not_active Expired - Lifetime
- 1977-06-01 CY CY1130A patent/CY1130A/xx unknown
- 1977-06-02 DE DE19772724989 patent/DE2724989A1/de not_active Withdrawn
- 1977-06-03 FR FR7717042A patent/FR2353530A1/fr active Granted
- 1977-06-03 JP JP6497377A patent/JPS52151161A/ja active Granted
- 1977-06-03 NL NL7706173A patent/NL7706173A/xx not_active Application Discontinuation
- 1977-06-03 DK DK248177A patent/DK248177A/da not_active Application Discontinuation
- 1977-06-03 SE SE7706520A patent/SE424861B/sv not_active IP Right Cessation
- 1977-06-03 CH CH688677A patent/CH641159A5/de not_active IP Right Cessation
-
1981
- 1981-11-10 KE KE3170A patent/KE3170A/xx unknown
- 1981-11-26 HK HK579/81A patent/HK57981A/xx unknown
-
1982
- 1982-12-30 MY MY180/82A patent/MY8200180A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
SE424861B (sv) | 1982-08-16 |
FR2353530B1 (sv) | 1981-07-17 |
CH641159A5 (de) | 1984-02-15 |
DK248177A (da) | 1977-12-06 |
KE3170A (en) | 1981-12-18 |
NL7706173A (nl) | 1977-12-07 |
AU2535677A (en) | 1978-11-23 |
HK57981A (en) | 1981-12-04 |
FR2353530A1 (fr) | 1977-12-30 |
DE2724989A1 (de) | 1977-12-15 |
JPS52151161A (en) | 1977-12-15 |
CY1130A (en) | 1982-02-19 |
IE45198L (en) | 1977-12-05 |
IE45198B1 (en) | 1982-07-14 |
AU509883B2 (en) | 1980-05-29 |
MY8200180A (en) | 1982-12-31 |
JPS613332B2 (sv) | 1986-01-31 |
US4140793A (en) | 1979-02-20 |
CA1070691A (en) | 1980-01-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
NUG | Patent has lapsed |
Ref document number: 7706520-9 Effective date: 19890725 Format of ref document f/p: F |