SE7703929L - Anestetika - Google Patents

Anestetika

Info

Publication number
SE7703929L
SE7703929L SE7703929A SE7703929A SE7703929L SE 7703929 L SE7703929 L SE 7703929L SE 7703929 A SE7703929 A SE 7703929A SE 7703929 A SE7703929 A SE 7703929A SE 7703929 L SE7703929 L SE 7703929L
Authority
SE
Sweden
Prior art keywords
anesthetics
Prior art date
Application number
SE7703929A
Other languages
English (en)
Inventor
G H Phillipps
G B Ewan
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of SE7703929L publication Critical patent/SE7703929L/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/008—Ketals at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0011—Unsubstituted amino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0016—Oximes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7703929A 1976-04-05 1977-04-04 Anestetika SE7703929L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB13707/76A GB1581234A (en) 1976-04-05 1976-04-05 11a - amino - 3a - hydroxysteroids

Publications (1)

Publication Number Publication Date
SE7703929L true SE7703929L (sv) 1978-10-27

Family

ID=10027931

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7703929A SE7703929L (sv) 1976-04-05 1977-04-04 Anestetika

Country Status (19)

Country Link
JP (1) JPS52142056A (sv)
AU (1) AU517206B2 (sv)
BE (1) BE853227A (sv)
DE (1) DE2715078A1 (sv)
DK (1) DK148677A (sv)
ES (1) ES457507A1 (sv)
FI (1) FI771046A (sv)
FR (2) FR2347382A1 (sv)
GB (1) GB1581234A (sv)
IE (1) IE45276B1 (sv)
IL (1) IL51816A (sv)
IT (1) IT1073232B (sv)
LU (1) LU77064A1 (sv)
NL (1) NL7703667A (sv)
NO (1) NO771197L (sv)
NZ (1) NZ183775A (sv)
PL (1) PL197186A1 (sv)
SE (1) SE7703929L (sv)
ZA (1) ZA772029B (sv)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3160797D1 (en) * 1980-07-16 1983-09-29 Glaxo Group Ltd 11-alpha-amino androstanes, pharmaceutical compositions containing them and processes for their preparation
GB2080308B (en) * 1980-07-16 1984-03-28 Glaxo Group Ltd 11-amino-androstane-17-carboxylates
AU8095782A (en) * 1981-03-02 1982-09-09 Glaxo Group Limited 11alpha-amine-3beta-hydroxy-androstanes
AU8428782A (en) * 1981-05-29 1982-12-02 Glaxo Group Limited 11-alpha-amino-androstane
ZA823782B (en) * 1981-05-29 1983-03-30 Glaxo Group Ltd 11 alpha-amino-androstanes
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
CZ300694A3 (en) * 1993-12-02 1996-05-15 Akzo Nobel Nv Substituted 2beta-morpholinandrostane derivatives, process of their preparation, their use for preparing pharmaceutical preparations and pharmaceutical compositions containing thereof
FR2910002B1 (fr) * 2006-12-13 2009-01-30 Sanofi Aventis Sa Nouveau procede pour l'obtention diastereoselective d'une amine primaire chirale sur un steroide
JP2010037243A (ja) * 2008-08-04 2010-02-18 Mitsubishi Rayon Co Ltd ノルボルネンラクトンモノマーの製造方法
JP2014528485A (ja) 2011-10-14 2014-10-27 セージ セラピューティクス， インコーポレイテッド ３，３−二置換１９−ノルプレグナン化合物およびその使用
IL286348B2 (en) 2012-01-23 2023-04-01 Sage Therapeutics Inc Pharmaceutical preparations that include allopregnanolone
KR102305359B1 (ko) 2012-08-21 2021-09-24 세이지 테라퓨틱스, 인크. 간질 또는 간질지속 상태를 치료하는 방법
CN117304245A (zh) 2013-04-17 2023-12-29 萨奇治疗股份有限公司 刺激神经活性的19-去甲类固醇及其使用方法
WO2014169831A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof
CN105339381B (zh) 2013-04-17 2018-04-27 萨奇治疗股份有限公司 19-去甲c3,3-二取代的c21-n-吡唑基类固醇及其使用方法
WO2014169836A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
RS61733B1 (sr) * 2013-07-19 2021-05-31 Sage Therapeutics Inc Neuroaktivni steroidi, njihove kompozicije i upotrebe
HUE052308T2 (hu) 2013-08-23 2021-04-28 Sage Therapeutics Inc Neuroaktív szteroidok, készítmények és alkalmazásuk
US10246482B2 (en) 2014-06-18 2019-04-02 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
ES2808855T3 (es) 2014-10-16 2021-03-02 Sage Therapeutics Inc Composiciones y métodos para tratar trastornos del SNC
NZ769008A (en) 2014-10-16 2024-03-22 Sage Therapeutics Inc Compositions and methods for treating cns disorders
PT3224269T (pt) * 2014-11-27 2020-06-01 Sage Therapeutics Inc Composições e métodos para tratamento de distúrbios do snc
ES2857082T3 (es) 2015-01-26 2021-09-28 Sage Therapeutics Inc Composiciones y métodos para el tratamiento de trastornos del SNC
US10329320B2 (en) 2015-02-20 2019-06-25 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
RU2766155C2 (ru) 2016-03-08 2022-02-08 Сейдж Терапьютикс, Инк. Нейроактивные стероиды, их композиции и применения
CA3030413A1 (en) 2016-07-11 2018-01-18 Sage Therapeutics, Inc. C17, c20, and c21 substituted neuroactive steroids and their methods of use
EP4406602A2 (en) 2016-07-11 2024-07-31 Sage Therapeutics, Inc. C7, c12, and c16 substituted neuroactive steroids and their methods of use
JP2021506904A (ja) * 2017-12-22 2021-02-22 セージ セラピューティクス， インコーポレイテッド Ｃｎｓ障害の処置のための組成物および方法
KR20210112318A (ko) 2018-12-05 2021-09-14 세이지 테라퓨틱스, 인크. 신경활성 스테로이드 및 이의 사용 방법
AR119047A1 (es) 2019-05-31 2021-11-17 Sage Therapeutics Inc Esteroides neuroactivos como moduladores de gabaa y su uso en el tratamiento de trastornos del snc
AU2020304673A1 (en) * 2019-06-27 2022-01-20 Sage Therapeutics, Inc. Compositions and methods for treating CNS disorders
BR112021026445A2 (pt) * 2019-06-27 2022-03-08 Sage Therapeutics Inc Composições e métodos para tratar distúrbios de cns

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2982775A (en) * 1957-05-06 1961-05-02 Schering Corp 11-oximino-, amino- and acylaminosteroids

Also Published As

Publication number Publication date
DK148677A (da) 1977-10-06
IT1073232B (it) 1985-04-13
BE853227A (fr) 1977-10-04
IE45276B1 (en) 1982-07-28
IL51816A (en) 1981-09-13
FR2347382B1 (sv) 1982-01-08
IL51816A0 (en) 1977-06-30
GB1581234A (en) 1980-12-10
AU517206B2 (en) 1981-07-16
NL7703667A (nl) 1977-10-07
JPS52142056A (en) 1977-11-26
AU2394277A (en) 1978-10-12
NO771197L (no) 1977-10-06
NZ183775A (en) 1979-12-11
FI771046A (sv) 1977-10-06
ZA772029B (en) 1978-11-29
PL197186A1 (pl) 1979-06-18
ES457507A1 (es) 1978-03-16
LU77064A1 (sv) 1979-01-18
DE2715078A1 (de) 1977-10-13
IE45276L (en) 1977-10-05
FR2485020A1 (fr) 1981-12-24
FR2347382A1 (fr) 1977-11-04

Similar Documents

Publication Publication Date Title
SE7703929L (sv) Anestetika
DK154399C (da) Inhalationsapparat
DK153523C (da) Inhalationsapparat
FR2351580A1 (fr) Moisonneuse-faucheuse
FI53561C (fi) Belastningsvals i rullmaskin
PT66710A (de) Dampfbuegelautomat
FI773337A (fi) Teleskopisk anordning
SE397637B (sv) Magnetomrorare
FI763081A (fi) Diaram
FI773402A (fi) Sugpump foer livraeddningsaendamaol
FI773432A (fi) Vaendbart monterad pneumatiskt styrd utloesningskrokanordning
DD131101A1 (de) Maximalleistungsueberwachungsgeraet
FI773065A (fi) Elektronkanoner foer anvaendning i katodstraolsroer
FI771699A (fi) Foerbaettrad stumpaenda foer termoplastroer
DK277976A (da) Friture-gryde
BE856621A (fr) Elektrisch bedienbare ponsmachine
FI773066A (fi) Leksak
FI773200A (fi) Rullvaexlingsanordning i banupprullningsmaskiner
BR7706948A (pt) Conjunto percussor
FI762440A (fi) Bergborrningsfoerfarande
DK238577A (da) Thiazolcardiovaskulere midler
IT1086071B (it) Perfluoroal cansolfammidi alcossilate
FI54018C (fi) Belastningskompenserad hydrostatisk effekttransmissionsanordning
DD129535A1 (de) Trennschleifkoerper
DK157371C (da) Afloebsbroend