SE431757B - Analogiforfaranden for framstellning av nya kortikoider - Google Patents

Analogiforfaranden for framstellning av nya kortikoider

Info

Publication number
SE431757B
SE431757B SE7711038A SE7711038A SE431757B SE 431757 B SE431757 B SE 431757B SE 7711038 A SE7711038 A SE 7711038A SE 7711038 A SE7711038 A SE 7711038A SE 431757 B SE431757 B SE 431757B
Authority
SE
Sweden
Prior art keywords
preparation
analogy
procedures
new corticoids
corticoids
Prior art date
Application number
SE7711038A
Other languages
English (en)
Other versions
SE7711038L (sv
Inventor
K Annen
H Laurent
H Hofmeister
R Wiechert
H Wendt
J F Kapp
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of SE7711038L publication Critical patent/SE7711038L/sv
Publication of SE431757B publication Critical patent/SE431757B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
SE7711038A 1976-10-04 1977-10-03 Analogiforfaranden for framstellning av nya kortikoider SE431757B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2645104A DE2645104C2 (de) 1976-10-04 1976-10-04 11β-Hydroxy-1,4,8-pregnatrien-3,20-dion-Derivate und Verfahren zu ihrer Herstellung

Publications (2)

Publication Number Publication Date
SE7711038L SE7711038L (sv) 1978-04-05
SE431757B true SE431757B (sv) 1984-02-27

Family

ID=5989828

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7711038A SE431757B (sv) 1976-10-04 1977-10-03 Analogiforfaranden for framstellning av nya kortikoider

Country Status (31)

Country Link
US (2) US4176126A (sv)
JP (1) JPS5359655A (sv)
AT (1) AT358201B (sv)
AU (1) AU519212B2 (sv)
BE (1) BE859350A (sv)
BG (3) BG28264A3 (sv)
CA (1) CA1099255A (sv)
CH (4) CH634082A5 (sv)
CS (1) CS199510B2 (sv)
DD (1) DD132438A5 (sv)
DE (1) DE2645104C2 (sv)
DK (1) DK438377A (sv)
ES (1) ES462888A1 (sv)
FI (1) FI58644C (sv)
FR (1) FR2366312A1 (sv)
GB (1) GB1594371A (sv)
GR (1) GR65016B (sv)
HU (1) HU177757B (sv)
IE (1) IE45781B1 (sv)
IL (1) IL53031A (sv)
IT (1) IT1087057B (sv)
LU (1) LU78210A1 (sv)
NL (1) NL7710868A (sv)
NO (1) NO773361L (sv)
NZ (1) NZ185296A (sv)
PL (2) PL110367B1 (sv)
PT (1) PT67110B (sv)
RO (1) RO73519A (sv)
SE (1) SE431757B (sv)
SU (1) SU730311A3 (sv)
ZA (1) ZA775915B (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2510582B1 (fr) 1981-07-30 1986-05-30 Sipsy Steroides esterifies en la position 17 et thio-esterifies en la position 21, leur procede de preparation et leur application comme medicament
IL66432A0 (en) * 1981-08-04 1982-12-31 Plurichemie Anstalt Process for the preparation of steroidal esters
DE3243482A1 (de) * 1982-11-22 1984-05-24 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6(alpha)-methylkortikoide, ihre herstellung und verwendung
DE3248435A1 (de) * 1982-12-23 1984-06-28 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6(alpha)-methylprednisolon-derivate ihre herstellung und verwendung
US4512986A (en) * 1983-07-26 1985-04-23 Research Triangle Institute Progrestationally active steroids
JPH07116222B2 (ja) * 1989-10-26 1995-12-13 エスエス製薬株式会社 21―デスオキシプレドニゾロン―17―エステルの製造法
DE4333920A1 (de) * 1993-10-05 1995-04-13 Hoechst Ag Corticoid-17,21-dicarbonsäureester sowie Corticosteroid-17-carbonsäureester-21-kohlensäureester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE4433374A1 (de) * 1994-09-20 1996-03-21 Hoechst Ag 17-Desoxi-corticosteroid-21-/O/-Carbonsäure- ester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2808415A (en) * 1955-01-25 1957-10-01 Merck & Co Inc Delta4, 8(9)-3, 20-diketo-11, 17-dihydroxy-21-oxygenated-pregnadienes and processes of preparing the same
US2813882A (en) * 1955-01-25 1957-11-19 Merck & Co Inc delta-3, 20-diketo-17-hydroxy-11, 21-bis oxygenated-pregnadiene compounds and processes of preparing the same
GB1043347A (en) * 1963-05-10 1966-09-21 Glaxo Lab Ltd 17,21-orthoesters of steroids
GB1047518A (en) * 1963-06-11 1966-11-02 Glaxo Lab Ltd 17ª‡-monoesters of 11,17,21-trihydroxy steroid compounds
GB1026160A (en) * 1964-04-29 1966-04-14 American Cyanamid Co Pregnatrienes
US3813420A (en) * 1969-02-05 1974-05-28 American Home Prod 13-polycarbonalkyl-3,11,17,20,21-pentaoxygenated-18-norpregnenes
GB1440064A (en) * 1972-08-11 1976-06-23 Glaxo Lab Ltd Delta8-9- steroids of the pregnane series

Also Published As

Publication number Publication date
US4243664A (en) 1981-01-06
CA1099255A (en) 1981-04-14
LU78210A1 (sv) 1978-01-23
ES462888A1 (es) 1978-06-01
FI772921A (fi) 1978-04-05
JPS5359655A (en) 1978-05-29
PT67110B (de) 1979-03-14
DE2645104C2 (de) 1986-04-24
JPS6126554B2 (sv) 1986-06-20
IE45781L (en) 1978-04-04
NL7710868A (nl) 1978-04-06
FR2366312B1 (sv) 1980-02-01
CH634085A5 (de) 1983-01-14
ATA703477A (de) 1980-01-15
DD132438A5 (de) 1978-09-27
FR2366312A1 (fr) 1978-04-28
IT1087057B (it) 1985-05-31
US4176126A (en) 1979-11-27
PL110367B1 (en) 1980-07-31
CH634084A5 (de) 1983-01-14
IL53031A (en) 1981-06-29
AT358201B (de) 1980-08-25
NZ185296A (en) 1980-04-28
PL201162A1 (pl) 1979-01-29
IE45781B1 (en) 1982-12-01
GB1594371A (en) 1981-07-30
CS199510B2 (en) 1980-07-31
FI58644C (fi) 1981-03-10
PL111825B1 (en) 1980-09-30
DE2645104A1 (de) 1978-04-06
RO73519A (ro) 1981-06-22
DK438377A (da) 1978-04-05
PT67110A (de) 1977-11-01
CH634082A5 (de) 1983-01-14
BG28717A4 (en) 1980-06-16
ZA775915B (en) 1978-05-30
SE7711038L (sv) 1978-04-05
AU2915477A (en) 1979-04-05
HU177757B (en) 1981-12-28
SU730311A3 (ru) 1980-04-25
NO773361L (no) 1978-04-05
BE859350A (fr) 1978-04-04
CH634083A5 (de) 1983-01-14
GR65016B (en) 1980-06-13
AU519212B2 (en) 1981-11-19
BG28718A4 (en) 1980-06-16
FI58644B (fi) 1980-11-28
BG28264A3 (en) 1980-03-25
IL53031A0 (en) 1977-11-30

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