SE423234B - Forfarande for framstellning av den kristallina 2-formen av 2-/4-(2-furoyl)-piperazin-1-yl/-4 amino-6,7-dimetoxi-kinazolinhydroklorid - Google Patents

Forfarande for framstellning av den kristallina 2-formen av 2-/4-(2-furoyl)-piperazin-1-yl/-4 amino-6,7-dimetoxi-kinazolinhydroklorid

Info

Publication number
SE423234B
SE423234B SE7701624A SE7701624A SE423234B SE 423234 B SE423234 B SE 423234B SE 7701624 A SE7701624 A SE 7701624A SE 7701624 A SE7701624 A SE 7701624A SE 423234 B SE423234 B SE 423234B
Authority
SE
Sweden
Prior art keywords
dimetoxy
chinazoline
furoyl
piperazin
hydrochloride
Prior art date
Application number
SE7701624A
Other languages
English (en)
Swedish (sv)
Other versions
SE7701624L (sv
Inventor
E J Bianco
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of SE7701624L publication Critical patent/SE7701624L/
Publication of SE423234B publication Critical patent/SE423234B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
SE7701624A 1976-03-01 1977-02-14 Forfarande for framstellning av den kristallina 2-formen av 2-/4-(2-furoyl)-piperazin-1-yl/-4 amino-6,7-dimetoxi-kinazolinhydroklorid SE423234B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/662,937 US4092315A (en) 1976-03-01 1976-03-01 Novel crystalline forms of prazosin hydrochloride

Publications (2)

Publication Number Publication Date
SE7701624L SE7701624L (sv) 1977-09-02
SE423234B true SE423234B (sv) 1982-04-26

Family

ID=24659839

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7701624A SE423234B (sv) 1976-03-01 1977-02-14 Forfarande for framstellning av den kristallina 2-formen av 2-/4-(2-furoyl)-piperazin-1-yl/-4 amino-6,7-dimetoxi-kinazolinhydroklorid

Country Status (32)

Country Link
US (1) US4092315A (es)
JP (1) JPS604188B2 (es)
AR (1) AR210937A1 (es)
AU (1) AU506937B2 (es)
BE (1) BE851878A (es)
BG (1) BG29724A3 (es)
CA (1) CA1068269A (es)
CH (1) CH618436A5 (es)
CS (1) CS191332B2 (es)
DD (1) DD129652A5 (es)
DE (1) DE2708192C3 (es)
DK (1) DK145858C (es)
ES (1) ES8707447A1 (es)
FI (1) FI62082C (es)
FR (1) FR2372828A1 (es)
GB (1) GB1538713A (es)
HK (1) HK30881A (es)
HU (1) HU173641B (es)
IE (1) IE44522B1 (es)
IL (1) IL51481A (es)
LU (1) LU76868A1 (es)
MY (1) MY8100271A (es)
NL (1) NL169591C (es)
NO (1) NO146499C (es)
NZ (1) NZ183450A (es)
PL (1) PL105559B1 (es)
PT (1) PT66227B (es)
RO (1) RO73095A (es)
SE (1) SE423234B (es)
SU (1) SU644387A3 (es)
YU (1) YU41294B (es)
ZA (1) ZA77918B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1591490A (en) * 1977-08-04 1981-06-24 Abbott Lab 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate
MX5483E (es) * 1977-08-04 1983-08-23 Abbott Lab Procedimiento para la preparacion del dihidrato clorhidrato de 1-(4-amino-6,7-dimetoxi-2-quinazolinil)-4-(2-tetrahidrofuroil)piperazina
US4197301A (en) * 1978-10-16 1980-04-08 Allergan Pharmaceuticals, Inc. Topical ophthalmic use of Prazosin
FI67699C (fi) * 1979-01-31 1985-05-10 Orion Yhtymae Oy Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan
US4440769A (en) * 1983-02-11 1984-04-03 Abbott Laboratories 2-(4-Phenylalkanoylpiperazin-1-yl) quinazoline compounds, pharmaceutical compositions and method of producing α1 antagonistic activity
FI79107C (fi) * 1984-06-25 1989-11-10 Orion Yhtymae Oy Foerfarande foer framstaellning av stabil -form av prazosinhydroklorid.
US5322943A (en) * 1985-09-12 1994-06-21 The Upjohn Company Piperazine compounds which are substituted
US4601897A (en) * 1985-11-06 1986-07-22 Pfizer Inc. Prazosin-pirbuterol combination for bronchodilation
ATE72244T1 (de) * 1986-03-21 1992-02-15 Heumann Pharma Gmbh & Co Kristalline, wasserfreie sigma -form von 2-(4-(2furoyl-(2-piperazin)-1-yl>-4-amino-6,7- dimethoxychinazolinhydrochlorid und verfahren zu ihrer herstellung.
US5110927A (en) * 1987-12-31 1992-05-05 The United States Of America As Represented By The Department Of Health And Human Services Prazosin analog with increased selectivity and duration of action
JP2652272B2 (ja) * 1990-12-31 1997-09-10 住化ファインケム株式会社 １−（４−アミノ−６，７−ジメトキシ−２−キナゾリニル）−４−（２−テトラヒドロフロイル）ピペラジン塩酸塩の新規な結晶体および該結晶体の製造方法
GB9417310D0 (en) * 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
US5952003A (en) * 1996-08-01 1999-09-14 Novartis Corporation Terazosin capsules
EP0849264A1 (de) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Neue polymorphe Form von doxazosinmesylat (Form I)
ATE353892T1 (de) * 1996-12-20 2007-03-15 Heumann Pharma Gmbh & Co Neue polymorphe form von doxazosinmesylat (form iii)
EP0849265A1 (de) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Neue polymorphe Form von Doxazosin-Mesylat (Form II)
TR201818824T4 (tr) 2014-07-21 2019-01-21 Keir Mfg Inc Aerodinamik büküm çemberi.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3663706A (en) * 1969-09-29 1972-05-16 Pfizer Use of 2,4-diaminoquinazolines as hypotensive agents

Also Published As

Publication number Publication date
NZ183450A (en) 1979-03-16
BE851878A (fr) 1977-08-29
JPS604188B2 (ja) 1985-02-01
FR2372828A1 (fr) 1978-06-30
ZA77918B (en) 1977-12-28
SE7701624L (sv) 1977-09-02
PT66227B (en) 1978-07-14
DD129652A5 (de) 1978-02-01
RO73095A (ro) 1981-06-26
HU173641B (en) 1979-07-28
FI770634A (es) 1977-09-02
IL51481A0 (en) 1977-04-29
NL169591C (nl) 1982-08-02
ES545368A0 (es) 1978-06-01
CH618436A5 (es) 1980-07-31
NL7702123A (nl) 1977-09-05
CS191332B2 (en) 1979-06-29
US4092315A (en) 1978-05-30
IE44522L (en) 1977-09-01
MY8100271A (en) 1981-12-31
FR2372828B1 (es) 1980-02-01
YU49977A (en) 1983-12-31
GB1538713A (en) 1979-01-24
ES8707447A1 (es) 1987-08-16
IE44522B1 (en) 1981-12-30
DK86877A (da) 1977-09-02
JPS52105206A (en) 1977-09-03
NL169591B (nl) 1982-03-01
YU41294B (en) 1987-02-28
DK145858B (da) 1983-03-21
FI62082C (fi) 1982-11-10
DE2708192C3 (de) 1980-05-08
DE2708192A1 (de) 1977-09-08
SU644387A3 (ru) 1979-01-25
PL105559B1 (pl) 1979-10-31
AU2244377A (en) 1978-11-23
PT66227A (en) 1977-03-01
AR210937A1 (es) 1977-09-30
LU76868A1 (es) 1977-09-21
NO146499B (no) 1982-07-05
FI62082B (fi) 1982-07-30
IL51481A (en) 1980-09-16
DK145858C (da) 1983-09-12
NO770674L (no) 1977-09-02
DE2708192B2 (de) 1979-08-02
NO146499C (no) 1982-10-13
BG29724A3 (en) 1981-01-15
AU506937B2 (en) 1980-01-31
PL196354A1 (pl) 1978-02-27
HK30881A (en) 1981-07-10
CA1068269A (en) 1979-12-18

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