SE0301987D0 - New polypeptide - Google Patents

New polypeptide

Info

Publication number
SE0301987D0
SE0301987D0 SE0301987A SE0301987A SE0301987D0 SE 0301987 D0 SE0301987 D0 SE 0301987D0 SE 0301987 A SE0301987 A SE 0301987A SE 0301987 A SE0301987 A SE 0301987A SE 0301987 D0 SE0301987 D0 SE 0301987D0
Authority
SE
Sweden
Prior art keywords
polypeptide
methods
her2
sequence
nucleic acid
Prior art date
Application number
SE0301987A
Other languages
Swedish (sv)
Original Assignee
Affibody Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affibody Ab filed Critical Affibody Ab
Priority to SE0301987A priority Critical patent/SE0301987D0/en
Publication of SE0301987D0 publication Critical patent/SE0301987D0/en
Priority to DE602004018141T priority patent/DE602004018141D1/en
Priority to AU2004253835A priority patent/AU2004253835B2/en
Priority to CN200480019059.XA priority patent/CN1816563B/en
Priority to AT04749087T priority patent/ATE416190T1/en
Priority to CA2531238A priority patent/CA2531238C/en
Priority to PCT/SE2004/001049 priority patent/WO2005003156A1/en
Priority to US10/563,310 priority patent/US7993650B2/en
Priority to ES04749087T priority patent/ES2319426T3/en
Priority to JP2006518586A priority patent/JP4871126B2/en
Priority to DK04749087T priority patent/DK1641818T3/en
Priority to EP04749087A priority patent/EP1641818B1/en
Priority to HK06113134.4A priority patent/HK1092481A1/en
Priority to JP2011111531A priority patent/JP5689022B2/en

Links

Abstract

A polypeptide is provided, which has a binding affinity for HER2 and which is related to a domain of staphylococcal protein A (SPA) in that the sequence of the polypeptide corresponds to the sequence of the SPA domain having from 1 to about 20 substitution mutations. Nucleic acid encoding the polypeptide, as well as expression vector and host cell for expressing the nucleic acid, are also provided. Also provided is the use of such a polypeptide as a medicament, and as a targeting agent for directing substances conjugated thereto to cells overexpressing HER2. Methods, and kits for performing the methods, are also provided, which methods and kits rely on the binding of the polypeptide to HER2.
SE0301987A 2003-07-04 2003-07-04 New polypeptide SE0301987D0 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
SE0301987A SE0301987D0 (en) 2003-07-04 2003-07-04 New polypeptide
EP04749087A EP1641818B1 (en) 2003-07-04 2004-06-30 Polypeptides having binding affinity for her2
PCT/SE2004/001049 WO2005003156A1 (en) 2003-07-04 2004-06-30 Polypeptides having binding affinity for her2
AU2004253835A AU2004253835B2 (en) 2003-07-04 2004-06-30 Polypeptides having binding affinity for HER2
CN200480019059.XA CN1816563B (en) 2003-07-04 2004-06-30 Polypeptides having binding affinity for HER2
AT04749087T ATE416190T1 (en) 2003-07-04 2004-06-30 POLYPEPTIDES WITH BINDING AFFINITY FOR HER2
CA2531238A CA2531238C (en) 2003-07-04 2004-06-30 Polypeptides having binding affinity for her2
DE602004018141T DE602004018141D1 (en) 2003-07-04 2004-06-30 POLYPEPTIDES WITH BINDING SAFFINITY FOR HER2
US10/563,310 US7993650B2 (en) 2003-07-04 2004-06-30 Polypeptides having binding affinity for HER2
ES04749087T ES2319426T3 (en) 2003-07-04 2004-06-30 POLYPEPTIDES PRESENTING AFFINITY OF UNION BY HER-2.
JP2006518586A JP4871126B2 (en) 2003-07-04 2004-06-30 Polypeptide having binding affinity for HER2
DK04749087T DK1641818T3 (en) 2003-07-04 2004-06-30 Polypeptides that have binding affinity for HER2
HK06113134.4A HK1092481A1 (en) 2003-07-04 2006-11-30 Polypeptides having binding affinity for her2
JP2011111531A JP5689022B2 (en) 2003-07-04 2011-05-18 Polypeptide having binding affinity for HER2

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0301987A SE0301987D0 (en) 2003-07-04 2003-07-04 New polypeptide

Publications (1)

Publication Number Publication Date
SE0301987D0 true SE0301987D0 (en) 2003-07-04

Family

ID=27731108

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0301987A SE0301987D0 (en) 2003-07-04 2003-07-04 New polypeptide

Country Status (2)

Country Link
CN (1) CN1816563B (en)
SE (1) SE0301987D0 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2077272A1 (en) * 2007-12-21 2009-07-08 Affibody AB Polypeptide libraries with a predetermined scaffold
EP2072525A1 (en) * 2007-12-21 2009-06-24 Affibody AB New polypeptides having affinity for HER2
WO2011038301A2 (en) * 2009-09-25 2011-03-31 Xoma Technology Ltd. Screening methods
EP2654914B1 (en) * 2010-12-20 2018-05-30 GE Healthcare BioProcess R&D AB Affinity chromatography matrix
CN102100914A (en) * 2010-12-21 2011-06-22 陈顺基 Artificial oil body carrier for targeted therapy of mastocarcinoma as well as preparation method and application thereof
CN105198973B (en) * 2014-06-18 2019-01-25 上海交通大学 Staphylococcus protein A Z structural domain derivative and application thereof
KR101964619B1 (en) * 2014-09-29 2019-04-02 후지필름 가부시키가이샤 Antibody-binding polypeptide, antibody-binding fusion polypeptide, and adsorbent material
EP4142806A1 (en) * 2020-04-30 2023-03-08 Hober Biotech AB Visualization of her2 expression in human patients
CN111848746A (en) * 2020-08-08 2020-10-30 四川大学华西医院 Binding protein for targeted binding to HER2, and preparation method and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9901379D0 (en) * 1999-04-19 1999-04-19 Pharmacia & Upjohn Ab Receptor structures
GB0017720D0 (en) * 2000-07-19 2000-09-06 Got A Gene Ab Modified virus

Also Published As

Publication number Publication date
CN1816563A (en) 2006-08-09
CN1816563B (en) 2011-02-09

Similar Documents

Publication Publication Date Title
DK1641818T3 (en) Polypeptides that have binding affinity for HER2
SE0400274D0 (en) New polypeptide
DK1005540T3 (en) IKK-beta proteins, nucleic acids and methods
EA200801509A1 (en) HUMAN MONOCLONAL ANTIBODIES TO PROTEINTHYROSINKINASE 7 (PTK7) AND METHODS OF APPLICATION OF ANTIBODIES AGAINST PTK7
UA97473C2 (en) Normal;heading 1;heading 2;heading 3;ANTIBODIES DIRECTED TO HER-3 AND USES THEREOF
NO20080362L (en) CD19 antibodies and their uses
BR0315666A (en) A34 and a33 type 3 dna, proteins, their antibodies and treatment methods using the same
WO2005097185A3 (en) Irta-5 antibodies and their uses
DE602005016712D1 (en) RTER DNA
MXPA02012743A (en) Il-17 molecules and uses thereof.
HUP0500345A2 (en) Compositions and methods for the therapy and diagnosis of lung cancer
WO2006076691A8 (en) Irta-2 antibodies and their uses
WO2007018619A3 (en) Chimeric therapeutic agents
WO2005003296A3 (en) Albumin fusion proteins
BR0213303A (en) Direct Bleach Binding Proteins
CY1110868T1 (en) Minimal DNA Sequence That Acts as Chromatin Insulator and Its Use in Protein Expression
ATE522541T1 (en) BACTERIAL ADHESIN CONFORMERS
ATE490268T1 (en) TNF-ALHPA BINDING POLYPEPTIDE, USES THEREOF AND METHODS USING THE SAME
DE60041243D1 (en) USE OF A NEW LYSYL OXIDASE-RELATED PROTEIN
SE0301987D0 (en) New polypeptide
EP2392655A3 (en) Coagulation factor VII polypeptides
WO2002036627A3 (en) Interferons, uses and compositions related thereto
DK1082423T3 (en) Cyclin E2 genes and proteins
AU2003287115A1 (en) Fluorescent proteins from copepoda species and methods for using same
WO2002102316A3 (en) Histone deacetylase and methods of use thereof