SE0301987D0 - New polypeptide - Google Patents
New polypeptideInfo
- Publication number
- SE0301987D0 SE0301987D0 SE0301987A SE0301987A SE0301987D0 SE 0301987 D0 SE0301987 D0 SE 0301987D0 SE 0301987 A SE0301987 A SE 0301987A SE 0301987 A SE0301987 A SE 0301987A SE 0301987 D0 SE0301987 D0 SE 0301987D0
- Authority
- SE
- Sweden
- Prior art keywords
- polypeptide
- methods
- her2
- sequence
- nucleic acid
- Prior art date
Links
Abstract
A polypeptide is provided, which has a binding affinity for HER2 and which is related to a domain of staphylococcal protein A (SPA) in that the sequence of the polypeptide corresponds to the sequence of the SPA domain having from 1 to about 20 substitution mutations. Nucleic acid encoding the polypeptide, as well as expression vector and host cell for expressing the nucleic acid, are also provided. Also provided is the use of such a polypeptide as a medicament, and as a targeting agent for directing substances conjugated thereto to cells overexpressing HER2. Methods, and kits for performing the methods, are also provided, which methods and kits rely on the binding of the polypeptide to HER2.
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0301987A SE0301987D0 (en) | 2003-07-04 | 2003-07-04 | New polypeptide |
EP04749087A EP1641818B1 (en) | 2003-07-04 | 2004-06-30 | Polypeptides having binding affinity for her2 |
PCT/SE2004/001049 WO2005003156A1 (en) | 2003-07-04 | 2004-06-30 | Polypeptides having binding affinity for her2 |
AU2004253835A AU2004253835B2 (en) | 2003-07-04 | 2004-06-30 | Polypeptides having binding affinity for HER2 |
CN200480019059.XA CN1816563B (en) | 2003-07-04 | 2004-06-30 | Polypeptides having binding affinity for HER2 |
AT04749087T ATE416190T1 (en) | 2003-07-04 | 2004-06-30 | POLYPEPTIDES WITH BINDING AFFINITY FOR HER2 |
CA2531238A CA2531238C (en) | 2003-07-04 | 2004-06-30 | Polypeptides having binding affinity for her2 |
DE602004018141T DE602004018141D1 (en) | 2003-07-04 | 2004-06-30 | POLYPEPTIDES WITH BINDING SAFFINITY FOR HER2 |
US10/563,310 US7993650B2 (en) | 2003-07-04 | 2004-06-30 | Polypeptides having binding affinity for HER2 |
ES04749087T ES2319426T3 (en) | 2003-07-04 | 2004-06-30 | POLYPEPTIDES PRESENTING AFFINITY OF UNION BY HER-2. |
JP2006518586A JP4871126B2 (en) | 2003-07-04 | 2004-06-30 | Polypeptide having binding affinity for HER2 |
DK04749087T DK1641818T3 (en) | 2003-07-04 | 2004-06-30 | Polypeptides that have binding affinity for HER2 |
HK06113134.4A HK1092481A1 (en) | 2003-07-04 | 2006-11-30 | Polypeptides having binding affinity for her2 |
JP2011111531A JP5689022B2 (en) | 2003-07-04 | 2011-05-18 | Polypeptide having binding affinity for HER2 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0301987A SE0301987D0 (en) | 2003-07-04 | 2003-07-04 | New polypeptide |
Publications (1)
Publication Number | Publication Date |
---|---|
SE0301987D0 true SE0301987D0 (en) | 2003-07-04 |
Family
ID=27731108
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE0301987A SE0301987D0 (en) | 2003-07-04 | 2003-07-04 | New polypeptide |
Country Status (2)
Country | Link |
---|---|
CN (1) | CN1816563B (en) |
SE (1) | SE0301987D0 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2077272A1 (en) * | 2007-12-21 | 2009-07-08 | Affibody AB | Polypeptide libraries with a predetermined scaffold |
EP2072525A1 (en) * | 2007-12-21 | 2009-06-24 | Affibody AB | New polypeptides having affinity for HER2 |
WO2011038301A2 (en) * | 2009-09-25 | 2011-03-31 | Xoma Technology Ltd. | Screening methods |
EP2654914B1 (en) * | 2010-12-20 | 2018-05-30 | GE Healthcare BioProcess R&D AB | Affinity chromatography matrix |
CN102100914A (en) * | 2010-12-21 | 2011-06-22 | 陈顺基 | Artificial oil body carrier for targeted therapy of mastocarcinoma as well as preparation method and application thereof |
CN105198973B (en) * | 2014-06-18 | 2019-01-25 | 上海交通大学 | Staphylococcus protein A Z structural domain derivative and application thereof |
KR101964619B1 (en) * | 2014-09-29 | 2019-04-02 | 후지필름 가부시키가이샤 | Antibody-binding polypeptide, antibody-binding fusion polypeptide, and adsorbent material |
EP4142806A1 (en) * | 2020-04-30 | 2023-03-08 | Hober Biotech AB | Visualization of her2 expression in human patients |
CN111848746A (en) * | 2020-08-08 | 2020-10-30 | 四川大学华西医院 | Binding protein for targeted binding to HER2, and preparation method and application thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9901379D0 (en) * | 1999-04-19 | 1999-04-19 | Pharmacia & Upjohn Ab | Receptor structures |
GB0017720D0 (en) * | 2000-07-19 | 2000-09-06 | Got A Gene Ab | Modified virus |
-
2003
- 2003-07-04 SE SE0301987A patent/SE0301987D0/en unknown
-
2004
- 2004-06-30 CN CN200480019059.XA patent/CN1816563B/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN1816563A (en) | 2006-08-09 |
CN1816563B (en) | 2011-02-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1641818T3 (en) | Polypeptides that have binding affinity for HER2 | |
SE0400274D0 (en) | New polypeptide | |
DK1005540T3 (en) | IKK-beta proteins, nucleic acids and methods | |
EA200801509A1 (en) | HUMAN MONOCLONAL ANTIBODIES TO PROTEINTHYROSINKINASE 7 (PTK7) AND METHODS OF APPLICATION OF ANTIBODIES AGAINST PTK7 | |
UA97473C2 (en) | Normal;heading 1;heading 2;heading 3;ANTIBODIES DIRECTED TO HER-3 AND USES THEREOF | |
NO20080362L (en) | CD19 antibodies and their uses | |
BR0315666A (en) | A34 and a33 type 3 dna, proteins, their antibodies and treatment methods using the same | |
WO2005097185A3 (en) | Irta-5 antibodies and their uses | |
DE602005016712D1 (en) | RTER DNA | |
MXPA02012743A (en) | Il-17 molecules and uses thereof. | |
HUP0500345A2 (en) | Compositions and methods for the therapy and diagnosis of lung cancer | |
WO2006076691A8 (en) | Irta-2 antibodies and their uses | |
WO2007018619A3 (en) | Chimeric therapeutic agents | |
WO2005003296A3 (en) | Albumin fusion proteins | |
BR0213303A (en) | Direct Bleach Binding Proteins | |
CY1110868T1 (en) | Minimal DNA Sequence That Acts as Chromatin Insulator and Its Use in Protein Expression | |
ATE522541T1 (en) | BACTERIAL ADHESIN CONFORMERS | |
ATE490268T1 (en) | TNF-ALHPA BINDING POLYPEPTIDE, USES THEREOF AND METHODS USING THE SAME | |
DE60041243D1 (en) | USE OF A NEW LYSYL OXIDASE-RELATED PROTEIN | |
SE0301987D0 (en) | New polypeptide | |
EP2392655A3 (en) | Coagulation factor VII polypeptides | |
WO2002036627A3 (en) | Interferons, uses and compositions related thereto | |
DK1082423T3 (en) | Cyclin E2 genes and proteins | |
AU2003287115A1 (en) | Fluorescent proteins from copepoda species and methods for using same | |
WO2002102316A3 (en) | Histone deacetylase and methods of use thereof |