SE0101768D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE0101768D0
SE0101768D0 SE0101768A SE0101768A SE0101768D0 SE 0101768 D0 SE0101768 D0 SE 0101768D0 SE 0101768 A SE0101768 A SE 0101768A SE 0101768 A SE0101768 A SE 0101768A SE 0101768 D0 SE0101768 D0 SE 0101768D0
Authority
SE
Sweden
Prior art keywords
ring
phenyl
novel compounds
compounds
heteroaromatic ring
Prior art date
Application number
SE0101768A
Other languages
English (en)
Swedish (sv)
Inventor
William Brown
Christopher Walpole
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0101768A priority Critical patent/SE0101768D0/xx
Publication of SE0101768D0 publication Critical patent/SE0101768D0/xx
Priority to EEP200300542A priority patent/EE200300542A/xx
Priority to IL15863202A priority patent/IL158632A0/xx
Priority to JP2002591484A priority patent/JP2005508858A/ja
Priority to CA002446154A priority patent/CA2446154A1/en
Priority to AT02733704T priority patent/ATE333452T1/de
Priority to DE60213234T priority patent/DE60213234T2/de
Priority to ES02733704T priority patent/ES2268037T3/es
Priority to EP02733704A priority patent/EP1395575B1/en
Priority to RU2003131969/04A priority patent/RU2003131969A/ru
Priority to US10/477,641 priority patent/US6838468B2/en
Priority to MXPA03010437A priority patent/MXPA03010437A/es
Priority to PCT/SE2002/000947 priority patent/WO2002094811A1/en
Priority to CNA028101812A priority patent/CN1527828A/zh
Priority to PL02366388A priority patent/PL366388A1/xx
Priority to ARP020101813A priority patent/AR033757A1/es
Priority to CZ20033088A priority patent/CZ20033088A3/cs
Priority to SK1394-2003A priority patent/SK13942003A3/sk
Priority to BR0209668-4A priority patent/BR0209668A/pt
Priority to KR10-2003-7014945A priority patent/KR20030094424A/ko
Priority to HU0400975A priority patent/HUP0400975A2/hu
Priority to ZA200308636A priority patent/ZA200308636B/en
Priority to BG108329A priority patent/BG108329A/bg
Priority to IS7025A priority patent/IS7025A/is
Priority to CO03100162A priority patent/CO5540321A2/es
Priority to NO20035117A priority patent/NO20035117D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Psychology (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE0101768A 2001-05-18 2001-05-18 Novel compounds SE0101768D0 (sv)

Priority Applications (26)

Application Number Priority Date Filing Date Title
SE0101768A SE0101768D0 (sv) 2001-05-18 2001-05-18 Novel compounds
HU0400975A HUP0400975A2 (hu) 2001-05-18 2002-05-16 4-[Fenil-(4-piperinilidén)-metil]-benzamid-származékok és alkalmazásuk, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
PCT/SE2002/000947 WO2002094811A1 (en) 2001-05-18 2002-05-16 4-(penyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
PL02366388A PL366388A1 (en) 2001-05-18 2002-05-16 4-(penyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
JP2002591484A JP2005508858A (ja) 2001-05-18 2002-05-16 ４−（フェニル−ピペリジン−４−イリデン−メチル）−ベンズアミド誘導体及び疼痛、不安症又は胃腸障害の治療のためのその使用
CA002446154A CA2446154A1 (en) 2001-05-18 2002-05-16 4-(penyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
AT02733704T ATE333452T1 (de) 2001-05-18 2002-05-16 4-(penylpiperidin-4-ylidenmethyl)benzamidderiva e und deren verwendung zur behandlung von schmerzen,angstzuständen oder erkrankungen des magen-darm- trakts
DE60213234T DE60213234T2 (de) 2001-05-18 2002-05-16 4-(penylpiperidin-4-ylidenmethyl)benzamidderivate und deren verwendung zur behandlung von schmerzen, angstzuständen oder erkrankungen des magen-darm-trakts
ES02733704T ES2268037T3 (es) 2001-05-18 2002-05-16 Derivados 4-(fenil-piperidin-4-iliden-metil)-benzamida y su uso para el tratamiento del dolor, de la ansiedad o de trastornos gastrointestinnales.
EP02733704A EP1395575B1 (en) 2001-05-18 2002-05-16 4-(penyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
RU2003131969/04A RU2003131969A (ru) 2001-05-18 2002-05-16 Производные 4-(фенил-пиперидин-4-илиден-метил)-бензамида и их применение для лечения боли, тревоги или желудочно-кишечных расстройств
US10/477,641 US6838468B2 (en) 2001-05-18 2002-05-16 4-(phenyl-piperdin-4-ylidene methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
MXPA03010437A MXPA03010437A (es) 2001-05-18 2002-05-16 Derivados de 4-(fenil-piperidin-4-iliden-metil)-benzamida y su uso para tratar dolor, ansiedad o transtornos gastrointestinales.
EEP200300542A EE200300542A (et) 2001-05-18 2002-05-16 4-(fenüülpiperidiin-4-ülideenmetüül)bensamiidi derivaadid, nende valmistamine ja kasutamine valu, ärevuse või seedetrakti häirete ravis
CNA028101812A CN1527828A (zh) 2001-05-18 2002-05-16 4-(苯基-哌啶-4-基亚基-甲基)-苯甲酰胺衍生物及其在治疗疼痛、焦虑或胃肠疾病中的用途
IL15863202A IL158632A0 (en) 2001-05-18 2002-05-16 4-(phenyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
ARP020101813A AR033757A1 (es) 2001-05-18 2002-05-16 Derivados de 4-(fenil-piperidin-4-iliden-metil)benzamida
CZ20033088A CZ20033088A3 (cs) 2001-05-18 2002-05-16 @}Fenylpiperidin@ylidenmethylB benzamidové deriváty a jejich použití pro ošetřování bolestiŹ úzkosti nebo gastrointestinálních poruch
SK1394-2003A SK13942003A3 (sk) 2001-05-18 2002-05-16 4-(Fenylpiperidin-4-ylidénmetyl)benzamidové deriváty a ich použitie na liečbu bolesti, anxiety alebo gastrointestinálnych porúch
BR0209668-4A BR0209668A (pt) 2001-05-18 2002-05-16 Composto, uso do mesmo, composição farmacêutica, métodos para o tratamento da dor, de distúrbios gastrintestinais funcionais e da ansiedade, e, processo para preparar um composto
KR10-2003-7014945A KR20030094424A (ko) 2001-05-18 2002-05-16 4-(페닐-피페리딘-4-일리덴-메틸)-벤즈아미드 유도체 및통증, 불안증 또는 위장관 장애의 치료를 위한 그의 용도
ZA200308636A ZA200308636B (en) 2001-05-18 2003-11-05 4-(phenyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders.
BG108329A BG108329A (bg) 2001-05-18 2003-11-07 4-(фенил-пиперидин-4-илиден-метил)-бензамидни производни и тяхното използване за лечение на болка, потиснатост или стомашно-чревни разстройства
IS7025A IS7025A (is) 2001-05-18 2003-11-11 4-(fenýl-píperidín-4-ýlíden-metýl)-bensamíðafleiður og notkun þeirra til meðhöndlunar á sársauka, kvíða eða truflunum í maga og þörmum
CO03100162A CO5540321A2 (es) 2001-05-18 2003-11-12 Derivados de 4-(fenil-piperidin-4-iliden-metil)-benzamida y su uso para el tratamiento del dolor, ansiedad o desordenes gastrointestinales
NO20035117A NO20035117D0 (no) 2001-05-18 2003-11-17 4-(fenylpiperidin-4-yliden-metyl)-benzamidderivater og deres anvendelse forbehandling av smerte, angst eller gastrointestinale forstyrrelser

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0101768A SE0101768D0 (sv) 2001-05-18 2001-05-18 Novel compounds

Publications (1)

Publication Number Publication Date
SE0101768D0 true SE0101768D0 (sv) 2001-05-18

Family

ID=20284171

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0101768A SE0101768D0 (sv) 2001-05-18 2001-05-18 Novel compounds

Country Status (26)

Country Link
US (1) US6838468B2 (xx)
EP (1) EP1395575B1 (xx)
JP (1) JP2005508858A (xx)
KR (1) KR20030094424A (xx)
CN (1) CN1527828A (xx)
AR (1) AR033757A1 (xx)
AT (1) ATE333452T1 (xx)
BG (1) BG108329A (xx)
BR (1) BR0209668A (xx)
CA (1) CA2446154A1 (xx)
CO (1) CO5540321A2 (xx)
CZ (1) CZ20033088A3 (xx)
DE (1) DE60213234T2 (xx)
EE (1) EE200300542A (xx)
ES (1) ES2268037T3 (xx)
HU (1) HUP0400975A2 (xx)
IL (1) IL158632A0 (xx)
IS (1) IS7025A (xx)
MX (1) MXPA03010437A (xx)
NO (1) NO20035117D0 (xx)
PL (1) PL366388A1 (xx)
RU (1) RU2003131969A (xx)
SE (1) SE0101768D0 (xx)
SK (1) SK13942003A3 (xx)
WO (1) WO2002094811A1 (xx)
ZA (1) ZA200308636B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0101768D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
RU2005136524A (ru) * 2003-05-16 2006-06-27 Астразенека Аб (Se) Производные диарилметилиденпиперидина, способы их получения и их применение
JP4976134B2 (ja) 2003-10-01 2012-07-18 アドラー コーポレーション スピロ環複素環誘導体及びそれらを使用する方法
SE0400026D0 (sv) * 2004-01-09 2004-01-09 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
US7598261B2 (en) 2005-03-31 2009-10-06 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
US7576207B2 (en) 2006-04-06 2009-08-18 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
CN101534819A (zh) 2006-09-12 2009-09-16 阿得罗公司 含氮的螺环化合物用于增强认知功能的应用
MY148880A (en) 2006-10-20 2013-06-14 Astrazeneca Ab N-(2-hydroxyethyl)-n-methyl-4-(quinolin-8-yl(1-(thiazol-4-ylmethyl)piperidin-4-ylidene)methyl)benzamide, the process of making it as well as its use for the treatment of pain, anxiety and depression
KR200453972Y1 (ko) * 2009-08-31 2011-06-09 (주)아모레퍼시픽 잔량확인이 가능한 에어리스 화장품용기
PT3233825T (pt) * 2014-12-19 2020-07-15 Pharmnovo Ab Derivados de diarilmetilideno-piperidina e sua utilização como agonistas do recetor opioide delta

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2898339A (en) 1957-07-29 1959-08-04 Wm S Merrell Co N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine
US4581171A (en) 1983-07-27 1986-04-08 Janssen Pharmaceutica, N.V. [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones useful for treating psychotropic disorders
US4816586A (en) 1987-07-29 1989-03-28 Regents Of The University Of Minnesota Delta opioid receptor antagonists
US5140029A (en) 1989-01-09 1992-08-18 Janssen Pharmaceutica N.V. 2-aminopyrimidinone derivatives
US4939137A (en) 1989-06-28 1990-07-03 Ortho Pharmaceutical Corporation Ring-fused thienopyrimidinedione derivatives
US5683998A (en) 1991-04-23 1997-11-04 Toray Industries, Inc. Tricyclic triazolo derivatives, processes for producing the same and the uses of the same
US5574159A (en) 1992-02-03 1996-11-12 Delta Pharmaceuticals, Inc. Opioid compounds and methods for making therefor
GB9202238D0 (en) 1992-02-03 1992-03-18 Wellcome Found Compounds
SE9504661D0 (sv) 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
TW548271B (en) * 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
CA2316341A1 (en) 1997-12-24 1999-07-08 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(piperidin-4-yl)] aminobenzamides which bind to the delta-opioid receptor
SE0001208D0 (sv) * 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
SE0001207D0 (sv) 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
SE0101768D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds

Also Published As

Publication number Publication date
ZA200308636B (en) 2005-06-21
EP1395575A1 (en) 2004-03-10
CN1527828A (zh) 2004-09-08
JP2005508858A (ja) 2005-04-07
RU2003131969A (ru) 2005-05-10
KR20030094424A (ko) 2003-12-11
MXPA03010437A (es) 2004-03-09
NO20035117D0 (no) 2003-11-17
WO2002094811A1 (en) 2002-11-28
IL158632A0 (en) 2004-05-12
US6838468B2 (en) 2005-01-04
HUP0400975A2 (hu) 2004-08-30
BR0209668A (pt) 2004-04-20
CZ20033088A3 (cs) 2004-05-12
ATE333452T1 (de) 2006-08-15
SK13942003A3 (sk) 2004-04-06
IS7025A (is) 2003-11-11
EP1395575B1 (en) 2006-07-19
DE60213234T2 (de) 2007-06-14
ES2268037T3 (es) 2007-03-16
DE60213234D1 (de) 2006-08-31
CA2446154A1 (en) 2002-11-28
CO5540321A2 (es) 2005-07-29
PL366388A1 (en) 2005-01-24
AR033757A1 (es) 2004-01-07
US20040147553A1 (en) 2004-07-29
EE200300542A (et) 2004-02-16
BG108329A (bg) 2004-12-30

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