RU99118887A - Применение ингибиторов желудочно-кишечной липазы - Google Patents
Применение ингибиторов желудочно-кишечной липазыInfo
- Publication number
- RU99118887A RU99118887A RU99118887/14A RU99118887A RU99118887A RU 99118887 A RU99118887 A RU 99118887A RU 99118887/14 A RU99118887/14 A RU 99118887/14A RU 99118887 A RU99118887 A RU 99118887A RU 99118887 A RU99118887 A RU 99118887A
- Authority
- RU
- Russia
- Prior art keywords
- gastrointestinal lipase
- application
- lipase inhibitors
- gastrointestinal
- inhibitor
- Prior art date
Links
- 229940040461 Lipase Drugs 0.000 title claims 5
- 239000004367 Lipase Substances 0.000 title claims 5
- 230000002496 gastric Effects 0.000 title claims 5
- 239000003112 inhibitor Substances 0.000 title claims 5
- 102000004882 lipase Human genes 0.000 title claims 5
- 235000019421 lipase Nutrition 0.000 title claims 5
- 108090001060 lipase Proteins 0.000 title claims 5
- 230000002401 inhibitory effect Effects 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 3
- AHLBNYSZXLDEJQ-FWEHEUNISA-N Orlistat Chemical group CCCCCCCCCCC[C@H](OC(=O)[C@H](CC(C)C)NC=O)C[C@@H]1OC(=O)[C@H]1CCCCCC AHLBNYSZXLDEJQ-FWEHEUNISA-N 0.000 claims 2
- 208000001072 Type 2 Diabetes Mellitus Diseases 0.000 claims 2
- 108009000112 Type II diabetes mellitus Proteins 0.000 claims 2
- 229940079593 drugs Drugs 0.000 claims 2
- 229960001243 orlistat Drugs 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
Claims (4)
1. Применение ингибитора желудочно-кишечной липазы для приготовления лекарственных средств, назначаемых орально, для лечения или предупреждения сахарного диабета типа II.
2. Применение по п.1, где ингибитор желудочно-кишечной липазы представляет собой тетрагидролипстатин.
3. Лекарственное средство для орального введения, предназначенное для лечения или предупреждения сахарного диабета типа II, отличающееся тем, что оно содержит эффективное количество ингибитора желудочно-кишечной липазы.
4. Лекарственное средство для орального введения по п.3, где ингибитор желудочно-кишечной липазы представляет собой тетрагидролипстатин.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3738397P | 1997-02-05 | 1997-02-05 | |
US60/037,383 | 1997-02-05 |
Publications (2)
Publication Number | Publication Date |
---|---|
RU99118887A true RU99118887A (ru) | 2001-05-20 |
RU2201272C2 RU2201272C2 (ru) | 2003-03-27 |
Family
ID=21894047
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU99118887/14A RU2201272C2 (ru) | 1997-02-05 | 1998-01-29 | Применение ингибиторов желудочно-кишечной липазы |
Country Status (28)
Country | Link |
---|---|
US (1) | US6147108A (ru) |
EP (1) | EP1017408B1 (ru) |
JP (1) | JP2001509173A (ru) |
KR (1) | KR100479968B1 (ru) |
CN (1) | CN1154505C (ru) |
AR (1) | AR011106A1 (ru) |
AT (1) | ATE292975T1 (ru) |
AU (1) | AU740375B2 (ru) |
BR (1) | BR9807655A (ru) |
CA (1) | CA2278854C (ru) |
CZ (1) | CZ295567B6 (ru) |
DE (1) | DE69829763T2 (ru) |
DK (1) | DK1017408T3 (ru) |
ES (1) | ES2239799T3 (ru) |
HK (1) | HK1025251A1 (ru) |
HU (1) | HU230834B1 (ru) |
ID (1) | ID22650A (ru) |
IL (1) | IL131007A0 (ru) |
ME (1) | ME00578A (ru) |
NO (1) | NO324452B1 (ru) |
NZ (1) | NZ336755A (ru) |
PL (1) | PL191222B1 (ru) |
PT (1) | PT1017408E (ru) |
RU (1) | RU2201272C2 (ru) |
TR (1) | TR199901853T2 (ru) |
WO (1) | WO1998034630A1 (ru) |
YU (1) | YU34199A (ru) |
ZA (1) | ZA98753B (ru) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1017408B1 (en) * | 1997-02-05 | 2005-04-13 | F. Hoffmann-La Roche Ag | Use of tethrahydrolipstatin in the treatment of diabetes type ii |
AR025587A1 (es) * | 1999-09-13 | 2002-12-04 | Hoffmann La Roche | Formulaciones en dispersion que contienen inhibidores de lipasa |
AR025609A1 (es) | 1999-09-13 | 2002-12-04 | Hoffmann La Roche | Formulaciones lipidas solidas |
ES2324280T3 (es) | 2000-03-14 | 2009-08-04 | Unilever N.V. | Dominios variables de la cadena pesada de anticuerpos frente a lipasas dieteticas humanas y sus usos. |
US6828297B2 (en) * | 2001-06-04 | 2004-12-07 | Nobex Corporation | Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same |
US7053080B2 (en) * | 2001-09-21 | 2006-05-30 | Schering Corporation | Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors |
US9174176B2 (en) | 2003-01-09 | 2015-11-03 | Disperse Systems, Inc. | Ultrasonic dispersion apparatus, system, and method |
US7510849B2 (en) * | 2004-01-29 | 2009-03-31 | Glucolight Corporation | OCT based method for diagnosis and therapy |
EP2626368B1 (en) | 2004-07-19 | 2016-12-21 | Biocon Limited | Insulin-oligomer conjugates, formulations and uses thereof |
US8036727B2 (en) * | 2004-08-11 | 2011-10-11 | Glt Acquisition Corp. | Methods for noninvasively measuring analyte levels in a subject |
US7254429B2 (en) | 2004-08-11 | 2007-08-07 | Glucolight Corporation | Method and apparatus for monitoring glucose levels in a biological tissue |
CA2604653A1 (en) | 2005-04-13 | 2006-10-19 | Glucolight Corporation | Method for data reduction and calibration of an oct-based blood glucose monitor |
US8217025B2 (en) * | 2006-11-17 | 2012-07-10 | Harbor Therapeutics, Inc. | Drug screening and treatment methods |
EP2036575B1 (en) * | 2007-09-12 | 2010-08-18 | Mader S.r.l. | Pharmaceutical compositions for oral use for treating patients affected by obesity |
US20100317642A1 (en) * | 2007-10-15 | 2010-12-16 | Inventis Dds Pvt Limited | Pharmaceutical composition of orlistat |
AU2008313248B2 (en) | 2007-10-16 | 2012-04-26 | Biocon Limited | An orally administerable solid pharmaceutical composition and a process thereof |
US8768423B2 (en) | 2008-03-04 | 2014-07-01 | Glt Acquisition Corp. | Multispot monitoring for use in optical coherence tomography |
US8309107B2 (en) * | 2008-10-06 | 2012-11-13 | Banner Pharmacaps, Inc. | Stable solutions of orlistat for pharmaceutical dosage forms |
FR3017536B1 (fr) * | 2014-02-18 | 2017-05-26 | Univ La Rochelle | Compositions pour la prevention et/ou le traitement de pathologies liees a l'alpha-glucosidase |
JP2019515654A (ja) * | 2016-03-16 | 2019-06-13 | ザ ジェイ. デヴィッド グラッドストーン インスティテューツ | 肥満及び/又は糖尿病を処置するための方法及び組成物、並びに候補処置薬剤を識別するための方法及び組成物 |
US20190022061A1 (en) * | 2017-07-21 | 2019-01-24 | Kieu Hoang | Statins (Atorvastatin) can lower blood sugar level in diabetic |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1247547A (en) * | 1983-06-22 | 1988-12-28 | Paul Hadvary | Leucine derivatives |
CA1270837A (en) * | 1984-12-21 | 1990-06-26 | Hoffmann-La Roche Limited | Oxetanones |
CA1328881C (en) * | 1984-12-21 | 1994-04-26 | Pierre Barbier | Process for the manufacture of oxetanones |
CA2035972C (en) * | 1990-02-23 | 2006-07-11 | Martin Karpf | Process for the preparation of oxetanones |
US5298497A (en) * | 1990-05-15 | 1994-03-29 | E. R. Squibb & Sons, Inc. | Method for preventing onset of hypertension employing a cholesterol lowering drug |
US5130333A (en) * | 1990-10-19 | 1992-07-14 | E. R. Squibb & Sons, Inc. | Method for treating type II diabetes employing a cholesterol lowering drug |
US5190970A (en) * | 1990-10-19 | 1993-03-02 | E. R. Squibb & Sons, Inc. | Method for preventing onset of or treating Type II diabetes employing a cholesterol lowering drug alone or in combination with an ace inhibitor |
US5345056A (en) * | 1991-12-12 | 1994-09-06 | Motorola, Inc. | Plasma based soldering by indirect heating |
CA2098167C (en) * | 1992-06-24 | 2006-12-19 | Dorothea Isler | Foodstuffs and feedstuffs containing a lipase inhibitor |
TW381025B (en) * | 1993-08-05 | 2000-02-01 | Hoffmann La Roche | Pharmaceutical composition containing a glucosidase inhibitor and a lipase inhibitor |
JP3532999B2 (ja) * | 1995-03-24 | 2004-05-31 | 株式会社ロッテ | 新規なタンニン類およびこれを有効成分とするリパーゼ阻害剤 |
JPH09227398A (ja) * | 1996-02-20 | 1997-09-02 | Zeria Pharmaceut Co Ltd | 抗肥満剤 |
EP1017408B1 (en) * | 1997-02-05 | 2005-04-13 | F. Hoffmann-La Roche Ag | Use of tethrahydrolipstatin in the treatment of diabetes type ii |
US6004996A (en) * | 1997-02-05 | 1999-12-21 | Hoffman-La Roche Inc. | Tetrahydrolipstatin containing compositions |
-
1998
- 1998-01-29 EP EP98908008A patent/EP1017408B1/en not_active Revoked
- 1998-01-29 ES ES98908008T patent/ES2239799T3/es not_active Expired - Lifetime
- 1998-01-29 DK DK98908008T patent/DK1017408T3/da active
- 1998-01-29 KR KR10-1999-7006983A patent/KR100479968B1/ko not_active IP Right Cessation
- 1998-01-29 ID IDW990792A patent/ID22650A/id unknown
- 1998-01-29 ME MEP-903/08A patent/ME00578A/xx unknown
- 1998-01-29 HU HU0001014A patent/HU230834B1/hu unknown
- 1998-01-29 CZ CZ19992651A patent/CZ295567B6/cs not_active IP Right Cessation
- 1998-01-29 YU YU34199A patent/YU34199A/sh unknown
- 1998-01-29 CA CA2278854A patent/CA2278854C/en not_active Expired - Lifetime
- 1998-01-29 IL IL13100798A patent/IL131007A0/xx not_active IP Right Cessation
- 1998-01-29 PL PL334975A patent/PL191222B1/pl unknown
- 1998-01-29 PT PT98908008T patent/PT1017408E/pt unknown
- 1998-01-29 DE DE69829763T patent/DE69829763T2/de not_active Expired - Lifetime
- 1998-01-29 NZ NZ336755A patent/NZ336755A/en not_active IP Right Cessation
- 1998-01-29 AT AT98908008T patent/ATE292975T1/de active
- 1998-01-29 AU AU66169/98A patent/AU740375B2/en not_active Expired
- 1998-01-29 TR TR1999/01853T patent/TR199901853T2/xx unknown
- 1998-01-29 RU RU99118887/14A patent/RU2201272C2/ru active
- 1998-01-29 JP JP53371598A patent/JP2001509173A/ja active Pending
- 1998-01-29 ZA ZA98753A patent/ZA98753B/xx unknown
- 1998-01-29 CN CNB988023245A patent/CN1154505C/zh not_active Expired - Lifetime
- 1998-01-29 BR BR9807655-8A patent/BR9807655A/pt not_active Application Discontinuation
- 1998-01-29 WO PCT/EP1998/000468 patent/WO1998034630A1/en active IP Right Grant
- 1998-02-03 AR ARP980100471A patent/AR011106A1/es not_active Application Discontinuation
-
1999
- 1999-07-30 NO NO19993717A patent/NO324452B1/no not_active IP Right Cessation
- 1999-10-04 US US09/411,554 patent/US6147108A/en not_active Expired - Lifetime
-
2000
- 2000-07-21 HK HK00104500A patent/HK1025251A1/xx not_active IP Right Cessation
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