RU97102350A - ANTI-ADHESION AGENT - Google Patents

ANTI-ADHESION AGENT

Info

Publication number
RU97102350A
RU97102350A RU97102350/14A RU97102350A RU97102350A RU 97102350 A RU97102350 A RU 97102350A RU 97102350/14 A RU97102350/14 A RU 97102350/14A RU 97102350 A RU97102350 A RU 97102350A RU 97102350 A RU97102350 A RU 97102350A
Authority
RU
Russia
Prior art keywords
substance
use according
polysaccharide
chitosan
immobilized
Prior art date
Application number
RU97102350/14A
Other languages
Russian (ru)
Other versions
RU2155592C2 (en
Inventor
Ханссон Ханс-Арне
Йоханссон-Руден Гунилла
Ларм Олле
Original Assignee
Астра Актиеболаг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9402529A external-priority patent/SE9402529D0/en
Application filed by Астра Актиеболаг filed Critical Астра Актиеболаг
Publication of RU97102350A publication Critical patent/RU97102350A/en
Application granted granted Critical
Publication of RU2155592C2 publication Critical patent/RU2155592C2/en

Links

Claims (14)

1. Применение хитозана и полисахарида, иммобилизованного с ним и выбранного из гепарана, гепарин сульфата и декстран сульфата для получения вещества, способного предотвращать или существенно снижать нежелательную адгезию поврежденной ткани с прилегающей или окружающей тканями при залечивании ран.1. The use of chitosan and a polysaccharide immobilized with it and selected from heparan, heparin sulfate and dextran sulfate to obtain a substance that can prevent or significantly reduce unwanted adhesion of damaged tissue to adjacent or surrounding tissues when healing wounds. 2. Применение по п. 1, отличающееся тем, что полисахарид иммобилизован с хитозаном с помощью ионной связи. 2. The use according to claim 1, characterized in that the polysaccharide is immobilized with chitosan via an ionic bond. 3. Применение по п. 1, отличающееся тем, что полисахарид иммобилизован с хитозаном с помощью ковалентной связи. 3. The use according to claim 1, characterized in that the polysaccharide is immobilized with chitosan using a covalent bond. 4. Применение по любому из предшествующих пунктов, отличающееся тем, что полисахарид является гепарином или гепаран сульфатом. 4. The use according to any one of the preceding paragraphs, characterized in that the polysaccharide is heparin or heparan sulfate. 5. Применение по любому из предшествующих пунктов, отличающееся тем, что вещество имеет форму пленки или мембраны. 5. The use according to any one of the preceding paragraphs, characterized in that the substance is in the form of a film or membrane. 6. Применение по любому из пп. 1 - 4, отличающееся тем, что вещество имеет форму трубки или рукава. 6. The use according to any one of paragraphs. 1 to 4, characterized in that the substance is in the form of a tube or sleeve. 7. Применение по п. 6, отличающееся тем, что вещество находится в форме геля. 7. The use according to claim 6, characterized in that the substance is in the form of a gel. 8. Применение по п. 6, отличающееся тем, что вещество находится в форме порошка, аэрозоля или раствора. 8. The use according to claim 6, characterized in that the substance is in the form of a powder, aerosol or solution. 9. Применение по любому из предшествующих пунктов, отличающееся тем, что хитозан имеет степень N-ацетилирования максимально около 90%, и предпочтительно максимально около 50%. 9. The use according to any one of the preceding paragraphs, characterized in that the chitosan has a degree of N-acetylation of at most about 90%, and preferably at most about 50%. 10. Способ предотвращения или существенного снижения нежелательной адгезии тканей при заживлении ран, отличающийся тем, что в области залечиваемой раны применяют вещество (агент), включающее хитозан и полисахарид, иммобилизованный с ним, выбранный из гепарина, гепаран сульфата и декстран сульфата. 10. A method of preventing or significantly reducing unwanted tissue adhesion during wound healing, characterized in that a substance (agent) is used in the area of the wound to be healed, including chitosan and a polysaccharide immobilized with it, selected from heparin, heparan sulfate and dextran sulfate. 11. Способ по п. 10, отличающийся тем, что вещество применяют в форме пленки или мембраны. 11. The method according to p. 10, characterized in that the substance is used in the form of a film or membrane. 12. Способ по п. 10, отличающийся тем, что вещество применяют в форме геля. 12. The method according to p. 10, characterized in that the substance is used in the form of a gel. 13. Способ по п. 10, отличающийся тем, что вещество применяют в форме трубки или рукава. 13. The method according to p. 10, characterized in that the substance is used in the form of a tube or sleeve. 14. Способ по п. 10, отличающийся тем, что вещество применяют в форме порошка, аэрозоля или раствора. 14. The method according to p. 10, characterized in that the substance is used in the form of a powder, aerosol or solution.
RU97102350/14A 1994-07-19 1995-07-13 Anti-adhesive agent RU2155592C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9402529-3 1994-07-19
SE9402529A SE9402529D0 (en) 1994-07-19 1994-07-19 Anti-adherents

Publications (2)

Publication Number Publication Date
RU97102350A true RU97102350A (en) 1999-02-27
RU2155592C2 RU2155592C2 (en) 2000-09-10

Family

ID=20394769

Family Applications (1)

Application Number Title Priority Date Filing Date
RU97102350/14A RU2155592C2 (en) 1994-07-19 1995-07-13 Anti-adhesive agent

Country Status (21)

Country Link
EP (1) EP0772446B1 (en)
JP (1) JP4033485B2 (en)
KR (1) KR100395723B1 (en)
CN (1) CN1157569A (en)
AT (1) ATE226439T1 (en)
AU (1) AU708758B2 (en)
BR (1) BR9508323A (en)
CA (1) CA2194476C (en)
CZ (1) CZ287692B6 (en)
DE (1) DE69528654T2 (en)
DK (1) DK0772446T3 (en)
ES (1) ES2180649T3 (en)
FI (1) FI970201A0 (en)
HU (1) HUT77606A (en)
IS (1) IS1794B (en)
MX (1) MX9700442A (en)
NO (1) NO310222B1 (en)
NZ (1) NZ290218A (en)
RU (1) RU2155592C2 (en)
SE (1) SE9402529D0 (en)
WO (1) WO1996002258A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9402531L (en) * 1994-07-19 1996-01-20 Medicarb Ab wound healing agent
NL1011680C2 (en) 1999-03-26 2000-09-27 Nutricia Nv Food compositions containing lightly negatively charged, non-digestible polysaccharides and use thereof to reduce transport through tight junctions.
US6645947B1 (en) * 1999-05-20 2003-11-11 Chitogenics, Inc. Adhesive N, O-carboxymethylchitosan coatings which inhibit attachment of substrate-dependent cells and proteins
SE523243C3 (en) * 1999-09-28 2004-05-26 Medicarb Ab Antimicrobial preparation for treatment and prophylaxis
ES2169681B1 (en) * 2000-08-10 2003-10-01 Osfarma S L PRODUCTION METHOD OF QUITOSAN FILMS WITH A HIGH CAPACITY OF CELLULAR ADHERENCE, OBRENIDO PRODUCT AND APPLICATIONS.
KR20020066024A (en) * 2001-02-08 2002-08-14 굿젠 주식회사 An ointment composition and film comprising aqueous chitosan and heparin, and wound management products
CA2443471A1 (en) 2001-04-12 2002-10-24 Medicarb Ab An effervescent solid composition of matter
SE522529C2 (en) 2001-04-12 2004-02-17 Medicarb Ab Effervescent solid composition used for treating dermal wounds comprises chitosan or component releasing carbon dioxide in acidic environment
US7332179B2 (en) 2003-12-12 2008-02-19 Kimberly-Clark Worldwide, Inc. Tissue products comprising a cleansing composition
US7642395B2 (en) 2004-12-28 2010-01-05 Kimberly-Clark Worldwide, Inc. Composition and wipe for reducing viscosity of viscoelastic bodily fluids
PL2126106T3 (en) * 2007-02-23 2018-03-30 Sk Chemicals Co., Ltd. Process for producing and purifying factor viii and its derivatives
ES2619181T3 (en) * 2007-08-28 2017-06-23 Otago Innovation Limited Surgical hydrogel
PL235185B1 (en) 2008-07-02 2020-06-01 Univ Jagiellonski Application of network chitosan polymer in heparin removal
US8906883B2 (en) 2009-06-10 2014-12-09 Exthera Ab Treatment of oral mucositis by administering an ionic complex of chitosan and a negatively charged polysaccharide selected from heparin, heparan sulfate and dextran sulfate
CN108610437A (en) * 2013-03-14 2018-10-02 金珂生物医疗公司 Bio-compatible and biological absorbable derivative chitosan composite
CN103341217B (en) * 2013-06-13 2015-05-06 上海大学 Preparation method for film used for preventing postoperative tissue adhesion
KR101664444B1 (en) * 2013-12-13 2016-10-12 재단법인 유타 인하 디디에스 및 신의료기술개발 공동연구소 Biodegradable medical adhesive or sealant compositions
CN106362221B (en) * 2016-09-30 2019-06-21 天津大学 A kind of adherence preventing material and preparation method thereof with antibacterial promoting healing function
KR200490615Y1 (en) 2016-10-20 2020-01-13 주식회사 인트로컴퍼니 User-customized calendar
WO2019211483A1 (en) * 2018-05-04 2019-11-07 Bonoss Medical Aktiebolag A composition for reduction of scar formation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4326532A (en) * 1980-10-06 1982-04-27 Minnesota Mining And Manufacturing Company Antithrombogenic articles
JPS61253065A (en) * 1985-05-02 1986-11-10 片倉チツカリン株式会社 Medical composite material of chitosan derivative and collagen and its production

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