RU95104980A - Benzene derivatives, methods of their synthesis, pharmaceutical compositions containing thereof and methods of treatment - Google Patents

Benzene derivatives, methods of their synthesis, pharmaceutical compositions containing thereof and methods of treatment

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Publication number
RU95104980A
RU95104980A RU95104980/04A RU95104980A RU95104980A RU 95104980 A RU95104980 A RU 95104980A RU 95104980/04 A RU95104980/04 A RU 95104980/04A RU 95104980 A RU95104980 A RU 95104980A RU 95104980 A RU95104980 A RU 95104980A
Authority
RU
Russia
Prior art keywords
methods
synthesis
compounds
compositions containing
pharmaceutical compositions
Prior art date
Application number
RU95104980/04A
Other languages
Russian (ru)
Inventor
Фентон Гарри
Gb]
Дэвид Морли Эндрю
Норман Полфрейман Малькольм
Джеймс Рэтклифф Эндрю
Вилльям Шарп Брайан
Альфред Джеймс Статл Кит
Турайратнам Сукантини
Ивон Жак Ваше Бернар
Lk]
Fr]
Original Assignee
Рон-Пуленк Рорер Лимитед (GB)
Рон-Пуленк Рорер Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929215989A external-priority patent/GB9215989D0/en
Priority claimed from GB939314847A external-priority patent/GB9314847D0/en
Application filed by Рон-Пуленк Рорер Лимитед (GB), Рон-Пуленк Рорер Лимитед filed Critical Рон-Пуленк Рорер Лимитед (GB)
Publication of RU95104980A publication Critical patent/RU95104980A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

FIELD: organic chemistry. SUBSTANCE: invention relates to phenyl-containing compounds bound with aryl moiety by different links that can be used for inhibition of tumor necrosis factor. Invention relates to also compounds, their synthesis and pharmaceutical compositions containing thereof. Also, invention relates to pharmaceutical use of these compounds for inhibition of cyclic AMP-phosphodiesterase activity. EFFECT: improved method of synthesis.

Claims (1)

Изобретение направлено на фармацевтическое использование фенильных соединений, которые связаны с арильным фрагментом с помощью различных связей, для ингибирования фактора некроза опухоли. Изобретение направлено также на соединения, их получение и фармацевтические композиции, содержащие эти соединения. Кроме того, изобретение направлено на фармацевтическое использование соединений для ингибирования циклической АМР фосфодиэстеразы.The invention is directed to the pharmaceutical use of phenyl compounds that are linked to an aryl fragment via various bonds to inhibit tumor necrosis factor. The invention is also directed to compounds, their preparation and pharmaceutical compositions containing these compounds. In addition, the invention is directed to the pharmaceutical use of compounds for inhibiting cyclic AMP phosphodiesterase.
RU95104980/04A 1992-07-28 1993-07-28 Benzene derivatives, methods of their synthesis, pharmaceutical compositions containing thereof and methods of treatment RU95104980A (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
GB929215989A GB9215989D0 (en) 1992-07-28 1992-07-28 Novel compounds
GB9216006.8 1992-07-28
GB9216008.4 1992-07-28
GB9215989.6 1992-07-28
GB9216005.0 1992-07-28
GB9216764.2 1992-08-07
GB9310633.4 1993-05-21
GB9310938.7 1993-05-27
GB9311281.1 1993-06-01
GB939314847A GB9314847D0 (en) 1993-07-16 1993-07-16 New use
GB9314847.6 1993-07-16

Publications (1)

Publication Number Publication Date
RU95104980A true RU95104980A (en) 1997-04-27

Family

ID=48433160

Family Applications (1)

Application Number Title Priority Date Filing Date
RU95104980/04A RU95104980A (en) 1992-07-28 1993-07-28 Benzene derivatives, methods of their synthesis, pharmaceutical compositions containing thereof and methods of treatment

Country Status (1)

Country Link
RU (1) RU95104980A (en)

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