RU95104980A - Benzene derivatives, methods of their synthesis, pharmaceutical compositions containing thereof and methods of treatment
- Google Patents
Benzene derivatives, methods of their synthesis, pharmaceutical compositions containing thereof and methods of treatment
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Publication number
RU95104980A
RU95104980ARU95104980/04ARU95104980ARU95104980ARU 95104980 ARU95104980 ARU 95104980ARU 95104980/04 ARU95104980/04 ARU 95104980/04ARU 95104980 ARU95104980 ARU 95104980ARU 95104980 ARU95104980 ARU 95104980A
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Priority claimed from GB929215989Aexternal-prioritypatent/GB9215989D0/en
Priority claimed from GB939314847Aexternal-prioritypatent/GB9314847D0/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
FIELD: organic chemistry. SUBSTANCE: invention relates to phenyl-containing compounds bound with aryl moiety by different links that can be used for inhibition of tumor necrosis factor. Invention relates to also compounds, their synthesis and pharmaceutical compositions containing thereof. Also, invention relates to pharmaceutical use of these compounds for inhibition of cyclic AMP-phosphodiesterase activity. EFFECT: improved method of synthesis.
Claims (1)
Изобретение направлено на фармацевтическое использование фенильных соединений, которые связаны с арильным фрагментом с помощью различных связей, для ингибирования фактора некроза опухоли. Изобретение направлено также на соединения, их получение и фармацевтические композиции, содержащие эти соединения. Кроме того, изобретение направлено на фармацевтическое использование соединений для ингибирования циклической АМР фосфодиэстеразы.The invention is directed to the pharmaceutical use of phenyl compounds that are linked to an aryl fragment via various bonds to inhibit tumor necrosis factor. The invention is also directed to compounds, their preparation and pharmaceutical compositions containing these compounds. In addition, the invention is directed to the pharmaceutical use of compounds for inhibiting cyclic AMP phosphodiesterase.
RU95104980/04A1992-07-281993-07-28Benzene derivatives, methods of their synthesis, pharmaceutical compositions containing thereof and methods of treatment
RU95104980A
(en)
Derivatives of indolecarbazolimide, mixture of their isomers or the separate isomers and their salts and pharmaceutical composition showing activity inhibiting protein kinase c or kinase of the light myosin chain or immune reactions
1-ALKOXY-2-(ALKOXY OR CYCLOALKOXY)-4-(CYCLOTHIOALKYL OR CYCLOTHIOALKENYL)BENZENES AS INHIBITORS OF CYCLIC AMP PHOSPHODIESTERASE AND TUMOR NECROSIS FACTOR
New adenosine derivatives, methods of their synthesis, pharmaceutical compositions based on thereof, methods of preparing pharmaceutical compositions and their use