RU94003002A - Method of prolongation of thymolol therapeutic action
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Method of prolongation of thymolol therapeutic action
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Publication number
RU94003002A
RU94003002ARU94003002/14ARU94003002ARU94003002ARU 94003002 ARU94003002 ARU 94003002ARU 94003002/14 ARU94003002/14 ARU 94003002/14ARU 94003002 ARU94003002 ARU 94003002ARU 94003002 ARU94003002 ARU 94003002A
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Application filed by Научно-производственная фирма "Нарт"filedCriticalНаучно-производственная фирма "Нарт"
Priority to RU94003002ApriorityCriticalpatent/RU2089191C1/en
Publication of RU94003002ApublicationCriticalpatent/RU94003002A/en
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Publication of RU2089191C1publicationCriticalpatent/RU2089191C1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Abstract
FIELD: medicine. SUBSTANCE: invention relates to prolongation of thymolol therapeutic action that is one of noncardioselective β---adrenoblocking agent used for glaucoma treatment. Method involves the use of thymolol in combination with hyaluronic acid. Thymolol and hyaluronic acid were taken at mass ratio 1:(2-4) at solution concentration containing this mixture 0.01-0.05%. EFFECT: decreased thymolol dose, prolonged therapeutic action with respect to intraocular pressure decrease.
Claims (1)
Изобретение решает задачу уменьшения дозы тимолола и пролонгации его способности снижать внутриглазное давление. Указанный результат достигается тем, что в способе пролонгации терапевтического эффекта тимолола, включающем использование тимолола в комбинации с соединениями, усиливающими его способность снижать внутриглазное давление, в качестве соединения, усиливающего специфическое действие тимолола, используют гиалуроновую кислоту, при этом тимолол и гиалуроновую кислоту берут в массовом соотношении 1:2 - 4, а концентрация раствора, содержащего эту комбинацию, составляет 0,01 - 0,05%.The invention solves the problem of reducing the dose of timolol and prolonging its ability to reduce intraocular pressure. This result is achieved by the fact that in the method of prolonging the therapeutic effect of timolol, including the use of timolol in combination with compounds that enhance its ability to reduce intraocular pressure, hyaluronic acid is used as a compound that enhances the specific effect of timolol, while timolol and hyaluronic acid are taken in bulk a ratio of 1: 2 - 4, and the concentration of the solution containing this combination is 0.01 - 0.05%.
RU94003002A1994-01-281994-01-28Method of prolongation of physiological effect of thymolol with respect to intraocular pressure decreasing
RU2089191C1
(en)