RU94002006A -
THE HUMAN CELL HUMAN CULTURE NTN1 27 - PRODUCT OF THE HUMAN IMMUNODEFICIENCY VIRUS (HIV)
- Google Patents
THE HUMAN CELL HUMAN CULTURE NTN1 27 - PRODUCT OF THE HUMAN IMMUNODEFICIENCY VIRUS (HIV)
Info
Publication number
RU94002006A
RU94002006ARU94002006/13ARU94002006ARU94002006ARU 94002006 ARU94002006 ARU 94002006ARU 94002006/13 ARU94002006/13 ARU 94002006/13ARU 94002006 ARU94002006 ARU 94002006ARU 94002006 ARU94002006 ARU 94002006A
Научно-исследовательский институт эпидемиологии и микробиологии им.Н.Ф.Гамалеи РАМН
Filing date
Publication date
Application filed by Научно-исследовательский институт эпидемиологии и микробиологии им.Н.Ф.Гамалеи РАМНfiledCriticalНаучно-исследовательский институт эпидемиологии и микробиологии им.Н.Ф.Гамалеи РАМН
Priority to RU94002006ApriorityCriticalpatent/RU2067116C1/en
Priority claimed from RU94002006Aexternal-prioritypatent/RU2067116C1/en
Publication of RU94002006ApublicationCriticalpatent/RU94002006A/en
Application grantedgrantedCritical
Publication of RU2067116C1publicationCriticalpatent/RU2067116C1/en
102000004169proteins and genesHuman genes0.000claims1
108090000623proteins and genesProteins0.000claims1
Claims (1)
Штамм культуры клеток человека HTHIV27- продуцент вируса иммунодефицита человека (ВИЧ) получен путем клонирования с использованием техники лимитирующего разведения на фидерном слое. Штамм обладает стабильными культуральными свойствами и оптимально высокой персистентной продукцией вируса (в 100% клеток одновременно) без клеточной деструкции. Продуцируемый вирус высокоинфекционен для чувствительных клеток. Имеет полное представительство белков в иммуноблоке. Штамм может быть использован для высокочувствительной и высокоспецифичной диагностической системы на СПИД, для скрининга противовирусных препаратов, а также для решения фундаментальных вопросов патогенез в ВИЧ-инфекции.The strain of human cell culture HTHIV27-producing human immunodeficiency virus (HIV) was obtained by cloning using the technique of limiting dilution on the feeder layer. The strain possesses stable cultural properties and optimally high persistent production of the virus (in 100% of the cells at the same time) without cellular destruction. The virus produced is highly infectious for sensitive cells. It has a complete representation of proteins in the immunoblock. The strain can be used for a highly sensitive and highly specific diagnostic system for AIDS, for screening antiviral drugs, and also for solving fundamental problems of the pathogenesis of HIV infection.
RU94002006A1994-01-311994-01-31Strain of human cultured cells hthiy27 - a producer of human immunodeficiency virus
RU2067116C1
(en)
Amino acid residues 88 and 89 in the central hydrophilic region of human immunodeficiency virus type 1 Vif are critical for viral infectivity by enhancing the steady-state expression of Vif
Vector for the expression of proteins of the HIV-2 virus, one of the casual agents of AIDS, cell culture infected or transformed by this vector, proteins obtained, vaccine and antibodies obtained
VIRAL VECTOR AND RECOMBINANT DNA ENCODING PROTEIN F OF THE VIRUS CAUSAL AGENT OF THE S.I.D.A, CELL CULTURE INFECTED WITH THIS VECTOR, PROCESS FOR PREPARING THE PROTEIN, OBTAINED PROTEIN, VACCINE AND ANTIBODIES OBTAINED
Peptides capable of being recognized by antibodies induced against human immunodeficiency retrovirus(hiv-virus),their applications for diagnosis of infections caused by some of these viruses and,in case,to vaccination against aids
Multiple branch peptide constructions comprising from 2 to 16 branches of the peptide rqgys or from 8 to 16 branches of the peptide rqgy providing from the hiv gp41 glycoprotein